The Adult Children Study

What is the Adult Children Study?

The Adult Children Study is a research study that is enrolling volunteers ages 45 to 64 at the time of enrollment in order to help detect the earliest signs or markers of dementing illnesses, such as Alzheimer's disease.

How will this study help Alzheimer's disease research?

Research suggests there may be changes occurring in the brain long before the appearance of dementia. Should truly effective treatments for dementing illnesses become available, their biggest effect may be in preventing the occurrence of dementia. However, we need tools to identify asymptomatic individuals at high risk for the disease to allow potential treatments to have maximal benefit. To work towards this goal, we are asking you to consider volunteering for this research study.


Interviews about your memory and thinking in our office (2-3 hours)

Blood Sample

Blood sample to test DNA for genetic causes of AD

Cognitive Testing

Testing of your memory and thinking in our office (2-3 hours; view fact sheet)

Brain Scans

Brain scans using positron emission tomography (PET fact sheet)

Lumbar Puncture

A lumbar puncture is performed to examine spinal fluid (view fact sheet).


Up to $525 for time & effort

Who can volunteer?

You may be eligible if:

  • You are healthy and between the ages of 45 and 64 at the time of enrollment
  • Have a study partner (spouse, etc.) who will be interviewed about your memory and thinking. 
  • Have two parents who were never affected by AD and lived past 70 years of age
  • OR
  • Have a parent who developed AD before the age of 80

How often will I be seen?

You and a person who knows you well (a collateral source) will be asked to come to the Memory and Aging Project offices for evaluations of your memory and thinking every 3 years until you reach 65 years old. After age 65, participants will be evaluated on an annual basis.


Updates via a secure website or telephone will be completed during the years that you do not complete an in-office clinical assessment and psychometric testing.


If memory and thinking problems are detected during the course of your participation, you will be asked to come in for annual assessments.


You may also be contacted about participation in additional studies affiliated with the Alzheimer's Disease Research Center.

Points to Consider

Below are several points to consider when becoming a MAP volunteer.

  • Participation in each of the research activities is voluntary
  • Taking part in this study may or may not help you personally
  • Your participation is a chance to help others in the future by helping researchers find better ways to diagnose and treat Alzheimer disease
  • Taking part in this study does not take the place of medical care provided by your health care provider
  • Information collected about you is kept strictly confidential
How to Contact Us

A Memory and Aging Project (MAP) team member can provide you with information about the study and answer any questions you may have.

Please call (314) 286-2683 for further information.



Study Fact Sheets

Lumbar Puncture Fact Sheet

You can download a PDF copy of our Lumbar Puncture Fact Sheet by clicking the image below.

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