Abhi Iyer, PhD

Abhi earned her Ph.D. in Immunology from Indiana University School of Medicine, where she investigated cytokine signaling pathways involved in lipid antigen presentation to innate lymphocytes called Natural Killer T (NKT) cells. Her interest in neuroimmunology led her to study CD4+ T cell-mediated motor neuron survival in amyotrophic lateral sclerosis (ALS) and peripheral nerve injury during her postdoctoral training at IUSM. She later joined Washington University in St. Louis, contributing to preclinical testing of antisense oligonucleotides targeting astrocytic α2-Na+/K+ ATPase in ALS. Currently, in the Karch Lab, Abhi investigates microglia-specific genetic risk factors for primary tauopathies, Alzheimer's disease and related dementias by leveraging human microglia-like cells differentiated from patient-derived induced pluripotent stem cells.

• Email: iyera@nospam.wustl.edu