Researcher Publication Search

Name: Anne Fagan
Year: 2009

Reference:

Fagan AM, Mintun MA, Shah AR, Aldea P, Roe CM, Mach RH, Marcus D, Morris JC, Holtzman DM. Cerebrospinal fluid tau and ptau181 increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer’s disease. EMBO Molecular Medicine, 2009; 1:371-80. PMCID: PMC2806678

Name: Raphael Kopan
Year: 2009

Reference:

Hass MR, Sato C, Kopan R, Zhao G. Presenilin: RIP and beyond. Semin Cell Dev Biol. 2009, 20:201-210.PMCID: PMC2693421

Name: Anne Fagan
Year: 2009

Reference:

Hinrichs AL, Mintun MA, Head D, Fagan AM, Holtzman DM, Morris JC, Goate AM. Cortical binding of Pittsburgh Compound B, an endophenotype for genetic studies of Alzheimer’s disease. Biological Psychiatry, 2009; 67:581-583. PMCID: PMC2866645

Name: Randall Bateman
Year: 2009

Reference:

Kang JE, Lim MM, Bateman RJ, Lee JJ, Smyth LP, Cirrito JR, Fujiki N, Nishino S, Holtzman DM. Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle. Science. 2009 Nov 13;326(5955):1005-7. Epub 2009 Sep 24. PMID: 19779148

Name: Anne Fagan
Year: 2009

Reference:

Kauwe JS, Wang J, Mayo K, Morris JC, Fagan AM, Holtzman DM, Goate AM. Alzheimer’s disease risk variants show association with cerebrospinal fluid amyloid beta. Neurogenetics. 2009; 10:13-7. PMCID: PMC2726757

Name: Anne Fagan
Year: 2009

Reference:

Morris JC, Roe CM, Grant EA, Head D, Storandt M, Goate AM, Fagan AM, Holtzman DM, Mintun MA. Pittsburgh Compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer’s disease, Archives of Neurology, 2009; 66:1469-75. PMCID: PMC2798814

Name: Anne Fagan
Year: 2009

Reference:

Okereke OI, Xia W, Irizarry MC, Sun X, Qiu WQ, Fagan AM, Mehta PD, Hyman BT, Selkoe DJ, Grodstein F. Performance characteristics of plasma amyloid-beta 40 and 42 assays. Journal of Alzheimers Disease, 2009; 16:277-85. PMCID: PMC2737811

Name: Anne Fagan
Year: 2009

Reference:

Perrin RJ, Fagan AM, Holtzman DM. Multimodal techniques for diagnosis and prognosis of Alzheimer’s disease, Nature, 2009; 461:916-22. PMCID: PMC2810658

Name: Anne Fagan
Year: 2009

Reference:

Snider BJ, Fagan AM, Roe CM, Shah AR, Grant EA, Xiong C, Morris JC, Holtzman DM. Cerebrospinal fluid biomarkers and rate of cognitive decline in very mild dementia of the Alzheimer’s type. Archives of Neurology, 2009; 66:638-45. PMCID: PMC2759394

Name: Randall Bateman
Year: 2009

Reference:

Wildsmith KR, Han B, Bateman RJ. Method for the simultaneous quantitation of apolipoprotein E isoforms using tandem mass spectrometry. Anal Biochem. 2009 Dec 1;395(1):116-8. Epub 2009 Aug 3. PMID: 19653990

Name: Anne Fagan
Year: 2008

Reference:

Craig-Schapiro R, Fagan AM, Holtzman DM. Biomarkers of Alzheimer’s disease, Neurobiology of Disease, 2008; 35:128-140. PMCID: PMC2747727

Name: Randall Bateman
Year: 2008

Reference:

Elbert DL, Mawuenyega KG, Scott EA, Wildsmith KR, Bateman RJ. Stable isotope labeling tandem mass spectrometry (SILT): integration with peptide identification and extension to data-dependent scans. J Proteome Res. 2008 Oct;7(10):4546-56. Epub 2008 Sep 6. PMID: 18774841

Name: Anne Fagan
Year: 2008

Reference:

Kauwe JS, Cruchaga C, Mayo K, Fenoglio C, Bertelsen S, Nowotny P, Galimberti D, Scarpini E, Morris JC, Fagan AM, Holtzman DM, Goate AM. Variation in MAPT is associated with cerebrospinal fluid tau levels in the presence of amyloid-beta deposition. Proceedings of the National Academy of Science. USA, 2008; 105:8050-4. PMCID: PMC2430357

Name: Anne Fagan
Year: 2008

Reference:

Lemere CA, Oh J, Stanish HA, Peng Y, Pepivani I, Fagan AM, Yamaguchi H, Westmoreland SV, Mansfield KG. Cerebral amyloid-beta protein accumulation with aging in cotton-top tamarins: a model of early Alzheimer’s disease? Rejuvenation Research, 2008; 11:321-32 Accepted prior to April 7, 2008

Name: Randall Bateman
Year: 2007

Reference:

Bateman RJ, Munsell LY, Chen X, Holtzman DM, Yarasheski KE. Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates. J Am Soc Mass Spectrom. 2007 Jun;18(6):997-1006. Epub 2007 Feb 22. PMID: 17383190

Name: Randall Bateman
Year: 2007

Reference:

Bateman RJ, Munsell LY, Morris JC, Swarm R, Yarasheski KE, Holtzman DM. Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo. Nat Med. 2006 Jul;12(7):856-61. Epub 2006 Jun 25. PMID: 16799555

Name: Randall Bateman
Year: 2007

Reference:

Bateman RJ, Wen G, Morris JC, Holtzman DM. Fluctuations of CSF amyloid-beta levels: implications for a diagnostic and therapeutic biomarker. Neurology. 2007 Feb 27;68(9):666-9. PMID: 17325273

Name: Anne Fagan
Year: 2007

Reference:

Hu Y, Hosseini A, Kauwe JSK, Gross J, Cairns NJ, Goate AM, Fagan AM, Townsend RR, Holtzman DM Identification and validation of novel CSF biomarkers for early stages of Alzheimer’s disease. Proteomics – Clinical Applications, 2007; 1:1374-1384.

Name: Anne Fagan
Year: 2007

Reference:

Kauwe JS, Jacquart S, Chakraverty S, Wang J, Mayo K, Fagan AM, Holtzman DM, Morris JC, Goate AM. Extreme Cerebrospinal Fluid Amyloid Beta Levels Identify Family with Late-Onset Alzheimer’s Disease Presenilin 1 Mutation. Annals of Neurology 2007; 61(5):446-53.

Name: Anne Fagan
Year: 2007

Reference:

Kauwe JSK, Jacquart S, Chakraverty S, Wang J, Mayo K, Mintun M, Fagan AM, Holtzman DM, Morris JC, Goate AM. Use of cerebrospinal fluid amyloid-β levels as an endophenotype identifies a PSEN1 mutation causing Alzheimer’s disease in a late-onset family. Annals of Neurology, 2007; 61(5):446-53.

Name: Anne Fagan
Year: 2007

Reference:

Kauwe JSK, Jacquart S, Chakraverty S, Wang J, Mayo K, Mintun M, Fagan AM, Holtzman DM, Morris JC, Goate AM. Use of cerebrospinal fluid amyloid-β levels as an endophenotype identifies a PSEN1 mutation causing Alzheimer’s disease in a late-onset family. Annals of Neurology, 2007; 61(5):446-53.

Name: Raphael Kopan
Year: 2007

Reference:

Khandelwal A, Chandu D, Roe CM, Kopan R and Quatrano RS: Moonlighting activity of presenilin in plants is independent of γ-secretase and evolutionarily conserved. Proc Natl Acad Sci USA (2007) 104:13337-13342. PMC1948938

Name: Raphael Kopan
Year: 2007

Reference:

Khandelwal, A., Chandu, D., Roe, C.M., Kopan, R., and Quatrano, R.S. (2007). Moonlighting activity of presenilin in plants is independent of “-secretase and evolutionarily conserved. Proc Natl Acad Sci U S A 104, 13337-13342.

Name: Anne Fagan
Year: 2007

Reference:

Wahrle SE, Shah AR, Fagan AM, Smemo S, Kauwe JSK, Grupe A, Hinrichs A, Mayo K, Jiang H, Thal LJ, Goate AM, Holtzman DM. Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1 polymorphisms. Molecular Neurodegeneration, 2007; 12;2:7.

Name: Anne Fagan
Year: 2006

Reference:

Csernansky JG, Dong H, Fagan AM, Wang L, Xiong C, Holtzman DM, and Morris JC. Plasma cortisol and progression of dementia in subjects with Alzheimer-type dementia, American Journal of Psychiatry, 2006; 163: 2164-9.