Neurologists discuss the major milestones in identifying biomarkers for detecting early Alzheimer’s disease over the past two decades.
Progress in Early Detection and Treatment of Alzheimer’s Disease (Links to an external site)
Category: Alzheimer Diagnosis News
Researchers call for clinical trial globalization in Alzheimer’s (Links to an external site)
Globalization of ADRD clinical trials has become a pressing need as 68% of the people living with ADRD will reside in low-middle-income countries (LMICs) by 2025.
Equity for African Americans in Alzheimer’s disease (Links to an external site)
For 20 years, the Knight Alzheimer Disease Research Center has worked to boost diversity in clinical trials.
Alzheimer’s Disease: Blood Test May Detect Condition 3 Years Before Clinical Diagnosis (Links to an external site)
Scientists say they have developed a test that can potentially detect Alzheimer’s disease a few years before people typically get a clinical diagnosis.
How Alzheimer’s Disease Research Is Helping Scientists Find Ways To Better Diagnose, Prevent, Treat, and Ultimately Cure Alzheimer’s (Links to an external site)
A new diagnostic tool by C2N Diagnostics is an important new tool for physicians in the evaluation of Alzheimer disease. It could pave the way for earlier diagnosis and treatment and greater enrollment in clinical trials.
What causes Alzheimer’s? Study puts leading theory to ‘ultimate test’ (Links to an external site)
Scientists are launching a study designed to make or break the hypothesis that Alzheimer’s is caused by a sticky substance called beta-amyloid. The study will give an experimental anti-amyloid drug to people as young as 18 who have gene mutations that often cause Alzheimer’s to appear in their 30s or 40s.
$9 million to fund study of ‘jumping genes’ in Alzheimer’s (Links to an external site)
A five-year, $9 million grant from the National Institute on Aging of the National Institutes of Health (NIH) will fund research led by several investigators at Washington University School of Medicine in St. Louis and at the University of Texas at San Antonio to answer that question.
Better Cognitive Predictor in People at High Risk of Alzheimer’s Disease (Links to an external site)
The Alzheimer’s disease (AD) drug lecanemab’s recent success in Biogen’s Phase III clinical trials might have more to do with its effect in increasing levels of soluble amyloid-beta than in decreasing amyloid plaques in the brain, the findings of a new study published in the Journal of Alzheimer’s Disease on October 4, 2022, suggests.
Cruchaga awarded Zenith Fellowship Award (Links to an external site)
Carlos Cruchaga, PhD, the Barbara Burton and Reuben M. Morriss III Professor in psychiatry, is one of three Zenith Fellows selected this year and one of only 146 Alzheimer’s researchers chosen for the honor since it was created in 1991.
Washington University researcher finds Hispanic community more likely to develop Alzheimer’s (Links to an external site)
Dr. Jorge Llibre is a Washington University neurologist that researches Alzheimer’s. He says research shows the Hispanic community is two times more likely to develop Alzheimer’s or dementia than non-Hispanics.
Risk of Alzheimer’s dementia may be predicted with help of new tool (Links to an external site)
Using demographic information, brain imaging test results and genetic biomarkers, researchers at Washington University School of Medicine in St. Louis have developed an algorithm that can help provide people who volunteer for studies of aging with information about the risk each faces of developing dementia due to Alzheimer’s disease.
With early Alzheimer’s in the family, these sisters decided to test for the gene (Links to an external site)
New Alzheimer’s diagnoses more common among seniors who have had Covid-19, study finds (Links to an external site)
A recent study of more than 6 million people 65 and older found that seniors who had Covid-19 had a substantially higher risk of being diagnosed with Alzheimer’s disease within a year.
Preclinical Alzheimer’s disease biomarkers accurately predict cognitive and neuropathological outcomes (Links to an external site)
The detection of preclinical Alzheimer disease biomarkers is strongly predictive of future cognitive impairment and accurately predicts presence of Alzheimer disease neuropathology at autopsy.
Dr. John C. Morris discusses biomarkers. (Links to an external site)
Dr. John C. Morris, MD, FAAN shares what he learned as the guest editor of the June 2022 Continuum issue on Dementia which includes biomarkers.
How deep sleep keeps our brains intact (Links to an external site)
How St. Louis researchers are seeking ways to combat Alzheimer’s and dementia (Links to an external site)
Race of people given Alzheimer’s blood tests may affect interpretation of results (Links to an external site)
Three experimental blood tests used to identify people in early stages of Alzheimer’s disease perform differently in Black individuals compared to white individuals, according to a new study from Washington University School of Medicine in St. Louis.
Risky driving behaviors increase as common sleep disorder worsens (Links to an external site)
Diagnosing, treating sleep apnea may make driving safer for older adults
New blood test may accurately detect Alzheimer’s disease (Links to an external site)
Now, a blood test developed by researchers at Washington University School of Medicine, St. Louis, has shown promising results in detecting the early signs of AD.
ANA Investigates: A Podcast Series (Links to an external site)
On today’s show, we’ll focus on the future of biomarkers in Alzheimer’s disease. We know that amyloid beta and tau protein deposit long before patients with Alzheimer’s develop symptoms. If we could use biomarkers to detect this pathology early, and treat patients early, could we prevent the progression to dementia?
Could drugs prevent Alzheimer’s? These trials aim to find out (Links to an external site)
Could drugs prevent Alzheimer’s? These trials aim to find out
Damage early in Alzheimer’s disease ID’d via novel MRI approach (Links to an external site)
A research team at Washington University School of Medicine in St. Louis has identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs that have therapeutic potential against these targets.
Blood test for Alzheimer’s highly accurate in large, international study (Links to an external site)
A research team at Washington University School of Medicine in St. Louis has identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs that have therapeutic potential against these targets.
Blood test can predict presence of beta-amyloid in the brain, new study finds (Links to an external site)
A research team at Washington University School of Medicine in St. Louis has identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs that have therapeutic potential against these targets.
How a hyperactive cell in the brain might trigger Alzheimer’s disease (Links to an external site)
A research team at Washington University School of Medicine in St. Louis has identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs that have therapeutic potential against these targets.
Racial equity in Alzheimer’s research focus of $7 million in grants (Links to an external site)
A research team at Washington University School of Medicine in St. Louis has identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs that have therapeutic potential against these targets.
Blood tests could help screen anticipated flood of patients seeking new Alzheimer’s drug (Links to an external site)
When the U.S. government approved the Alzheimer’s disease drug aducanumab last month despite shaky evidence of clinical benefits, Suzanne Schindler saw an immediate consequence: “We’re going to have to do a lot more biomarker testing.” Schindler, a neurologist at the Washington University School of Medicine in St. Louis, expects many patients with memory problems will […]