The Dominantly Inherited Alzheimer Network (DIAN) is an international research effort focused on Dominantly Inherited Alzheimer disease (DIAD).

What is DIAD?

Dominantly Inherited Alzheimer disease is a rare form of Alzheimer’s that causes memory loss and dementia in individuals — typically while they are in their 30s to 50s. The disease affects less than 1% of the total population of people with Alzheimer’s. The aim of the Dominantly Inherited Alzheimer Network is to find solutions to treat or prevent this disease and, potentially, all forms of Alzheimer’s.

What makes up the Dominantly Inherited Alzheimer Network?

DIAN’s efforts, led by Washington University School of Medicine in St. Louis, consist of a long-term observational study as well as basic science studies and clinical trials. The work is conducted in multiple countries around the world and involves researchers, clinicians, genetic counselors, individuals and families, all of whom can connect with each other via the DIAN Expanded Registry and/or through participating research sites for clinical trials or an observational study. Opportunities to participate in international family conferences and webinars also are available.

Randall Bateman, MD, talks in the mass spectrometry part of his lab with research specialist Haiyan Liu on March 11, 2021. MATT MILLER/WASHINGTON UNIVERSITY SCHOOL OF MEDICINE