To facilitate an investigator’s resource request, the Knight ADRC is providing the links below. Please review each one before continuing to a request form. Failure to review the items below may result in an unnecessarily delayed request.
Knight ADRC Data Freeze Process
The Knight ADRC conducts a center-wide data freeze twice annually, with cutoff dates on March 31 and September 30. Following each cutoff, every Core is allotted one month to prepare, quality‑check, and finalize its data for inclusion as a module in the consolidated dataset. This structured process ensures that researchers have access to the most current, accurate, and rigorously vetted data.
Upon completion of the QC period, the Biostatistics Core Leader, Chengjie Xiong, PhD, announces the availability of the updated dataset. All data modules are subsequently shared in accordance with approved data requests through the Knight ADRC.
Latest version: Version 1
Published: 18 Feb 2026
DOI: 10.17632/7mmfmzkydg.1
Digital Commons Data@Becker: https://digitalcommonsdata.wustl.edu/datasets/7mmfmzkydg/1
Guidelines & Policies (8/05/2022)
Summary Data Tables (provided in real-time)
Clinical Core Codebooks:
- UDS version 4 (data collection 1/14/2025-present)
- Annotated ISP, UDS version 3, initial and follow-up (data collection 3/16/2015-1/13/2025)
- Annotated ISP, UDS version 2 (data collection 9/1/2005-3/15/2015)
- 2005 Clinical Core Codebook (data collection pre-NACC, 8/1979-8/31/2005)
- For further information on the UDS variables, please consult the NACC data site.
Psychometric Codebook (UDS version 4, 2/25/2026)
Diagnostic Impressions Page from ISP
Ready to submit a request?
Before you submit your request, we wish to avoid the situation where two investigators study the same research question to avoid duplication of effort and potential conflict. To determine if your topic has already been studied with our resources, please search our existing Data, Tissue and Participant resource requests. If you find that your topic or a related topic has been submitted, you may wish to contact the investigator to inquire about their findings to determine how you might proceed. You may also wish to collaborate or modify your request to avoid overlap.