The Knight ADRC has supported many investigators at Washington University and at other institutions over the years. We wish to avoid the situation where two investigators study the same research question to avoid duplication of effort and potential conflict. To determine if your topic has already been studied with our resources, please search our database. If you find that your topic or a related topic has been submitted, you may wish to contact the investigator to inquire about their findings to determine how you might proceed. You may wish to collaborate or modify your request to avoid overlap. The results below reflect requests made since online requests have been accepted. As such, not all fields will have data as certain information, such as aims, were not collected until recently. If an entry has been assigned an ID number (e.g. T1004), the full request has been submitted and is either approved, disapproved or in process. If an entry has no ID number, then it represents a submission that has not yet been reviewed. Search terms are applied across an entire requests application including variables not displayed below. A more specific, detailed search may yield better results depending upon your needs.
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Investigator: Gregory Zipfel, MD
Project Title: A Randomized, Investigator- and Subject-Blind, Sponsor-Open, Placebo-Controlled Study to Examine the
Date: [293]
Request ID: S1016
Aim 1: To look at the effect of a single intravenous (in the vein) dose of an investigational drug (PF-04
Aim 2: To explore how the body reacts to (pharmacokinetics) a single intravenous dose of the study drug (
Aim 3: To see how or if the study drug (PF-04360365) changes how much A is in blood or CSF after a singl
Aim 4: To describe the safety and tolerability of a single intravenous dose study drug (PF-04360365) in p
Investigator: Vijay Sharma
Project Title: Imaging Functional Pgp Transport at the Blood Brain Barrier in Alzheimer’s Disease
Date: [293]
Request ID: S1015
Aim 1: Compare the brain uptake of the Pgp substrate [Tc-99m]sestamibi in AD patients and healthy subjects
Aim 2: Compare the brain uptake of [Tc-99m]sestamibi with previously performed [C-11]PIB studies
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Investigator: Morris, John C.
Project Title: A multicenter trial of rofecoxib and naproxen in Alzheimer’s disease
Date: [293]
Request ID: S9914
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Investigator: Canfield, Rita H.
Project Title: Psychological and physical stressors of caregiving: Implications for physical health
Date: [293]
Request ID: S9913
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Investigator: Corbetta, Maurizio
Project Title: Functional Imaging Studies of Aphasia Recovery
Date: [293]
Request ID: S9911
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Investigator: Csernansky, John G.
Project Title: Cortical Degeneration and Treatment Response in DAT
Date: [293]
Request ID: S9910
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Investigator: Powers, William
Project Title: AIT-082 in Mild Alzheimer’s Disease Patients
Date: [293]
Request ID: S9906
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Investigator: Dyer, Carol
Project Title: Implications for Genetic Testing in Members of Families with Early-onset Familial Dementia
Date: [293]
Request ID: S9905
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Investigator: Cortese, Michael J.
Project Title: Basis and effect of semantic memory loss in semantic dementia
Date: [293]
Request ID: S9904
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Investigator: Palmer, Janice
Project Title: Experience of Spousal caregivers at nursing home placement
Date: [293]
Request ID: S0814
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