The Knight ADRC has supported many investigators at Washington University and at other institutions over the years. We wish to avoid the situation where two investigators study the same research question to avoid duplication of effort and potential conflict. To determine if your topic has already been studied with our resources, please search our database. If you find that your topic or a related topic has been submitted, you may wish to contact the investigator to inquire about their findings to determine how you might proceed. You may wish to collaborate or modify your request to avoid overlap. The results below reflect requests made since online requests have been accepted. As such, not all fields will have data as certain information, such as aims, were not collected until recently. If an entry has been assigned an ID number (e.g. T1004), the full request has been submitted and is either approved, disapproved or in process. If an entry has no ID number, then it represents a submission that has not yet been reviewed. Search terms are applied across an entire requests application including variables not displayed below. A more specific, detailed search may yield better results depending upon your needs.
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Investigator: John Morris
Project Title: Cognitive reserve, brain reserve, and immediate stroke outcomes
Date: December 21, 2021 at 5:18 pm
Request ID: D1018
Aim 1: To determine whether cognitive and brain reserve factors influence immediate reaction to stroke.
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Investigator: Denise Head
Project Title: Multiple Factors Influencing Brain Networks
Date: December 21, 2021 at 5:18 pm
Request ID: D1017
Aim 1: Examine age effects on brain networks across the lifespan
Aim 2: examine the influences of exercise, personality, amyloid and APOE genotype on brain networks
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Investigator: Catherine Roe
Project Title: Predicting Post-stroke Dementia: Brain Reserve, Cognitive Reserve, and Amyloid
Date: December 21, 2021 at 5:18 pm
Request ID: D1016
Aim 1: To obtain preliminary data for grant proposal
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Investigator: Tamara Hershey
Project Title: Case Study of Hypoglycemia vs. Controls
Date: December 21, 2021 at 5:18 pm
Request ID: D1010
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Investigator: Dr. James Brewer
Project Title: Imaging studies of brain structure and function in aging and dementia
Date: December 21, 2021 at 5:18 pm
Request ID: D1020
Aim 1: Examine the relationship between brain atrophy and functional decline in aging and dementia
Aim 2: Examine the relationship between brain atrophy and cellular biomarkers in aging and dementia
Aim 3: Examine the relationship between brain atrophy and genetic markers in aging and dementia
Aim 4: Examine the relationship between brain atrophy and intracranial amyloid load in aging and dementia
Investigator: Halley Hindman
Project Title: Physical Activity, Cognition, and Regional Brain Volumes
Date: December 21, 2021 at 5:18 pm
Request ID: D1021
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Investigator: Mingan Yang, Chengjie Xiong
Project Title: Biostat modelling for Alzheimer’s disease
Date: December 21, 2021 at 5:18 pm
Request ID: D1022
Aim 1: Develop flexible statistical methodology to study issues of Alzeheimer disease
Aim 2: To improve the current methods, to address some issues the medical researchers are interested in
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Investigator: Jingqin Luo, Chengjie Xiong, Ming an Yang
Project Title: Random change point modele for longitudinal cognitive dementia
Date: December 21, 2021 at 5:18 pm
Request ID: D1023
Aim 1: It is hypothesized that a change point exists
Aim 2: Alzheimer’s disease patients will experience accerlerated dementa after the change point
Aim 3: We will identify the change point in visuospatial score and logical memory jointly
Aim 4: The relationship between the two change points helps clinical utilization of the two change points
Investigator: Timothy M. Miller
Project Title: Understanding elevated SOD1 in CSF from AD patients
Date: December 21, 2021 at 5:18 pm
Request ID: D1024
Aim 1: Correlate SOD1 levels in CSF with other ADRC measurements on same patients
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Investigator: Csernansky, John G.
Project Title: Comparison of automatic analysis of hippocampal structure methods
Date: December 21, 2021 at 5:18 pm
Request ID: D0101
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