The Knight ADRC has supported many investigators at Washington University and at other institutions over the years. We wish to avoid the situation where two investigators study the same research question to avoid duplication of effort and potential conflict. To determine if your topic has already been studied with our resources, please search our database. If you find that your topic or a related topic has been submitted, you may wish to contact the investigator to inquire about their findings to determine how you might proceed. You may wish to collaborate or modify your request to avoid overlap. The results below reflect requests made since online requests have been accepted. As such, not all fields will have data as certain information, such as aims, were not collected until recently. If an entry has been assigned an ID number (e.g. T1004), the full request has been submitted and is either approved, disapproved or in process. If an entry has no ID number, then it represents a submission that has not yet been reviewed. Search terms are applied across an entire requests application including variables not displayed below. A more specific, detailed search may yield better results depending upon your needs.
Search Terms:
Investigator: Catherine M. Roe
Project Title: IMPROVING PRESYMPTOMATIC DETECTION OF IMPENDING ALZHEIMER’S DISEASE
Date: December 21, 2021 at 5:18 pm
Request ID: D1105
Aim 1: To examine how cognitive and brain reserve factors combine with AD biomarkers
Aim 2: To build biomarker models that yield individual risk profiles predicting the time of AD onset.
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Investigator: Jonathan Day
Project Title: Assessment of Current Alzheimer’s Disease Therapies Using Neuroimaging and CSF Biomarkers: A Pilot S
Date: December 21, 2021 at 5:18 pm
Request ID: D1106
Aim 1: Assess the effectiveness of AD therapies from a neuroimaging and biomarker standpoints
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Investigator: Jason Hassenstab
Project Title: Obesity, Insulin Sensitivity, and Functional Connectivity in Normal Aging
Date: December 21, 2021 at 5:18 pm
Request ID: D1107
Aim 1: Do CDR 0’s with obesity and insulin resistance perform poorly on memory and executive function?
Aim 2: Do CDR 0’s with obesity and insulin resistance have reduced functional connectivity?
Aim 3: Do CDR 0’s with obesity and insulin resistance have lower brain volumes/cortical thickness?
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Investigator: Mintun, Mark
Project Title: A Pilot Study of C-11 PIB Brain Uptake and Binding
Date: December 21, 2021 at 5:18 pm
Request ID: D0406
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Investigator: Brian Gordon
Project Title: The Influence of Brain Structure on Prospective Memory
Date: December 21, 2021 at 5:18 pm
Request ID: D1019
Aim 1: Explore the relationship of medial temporal lobe volume and focal prospective memory
Aim 2: Explore the relationship of prefrontal structures and non-focal prospective memory
Aim 3: Investigate the influence of disease and genetic status on the link between behavior and anatomy
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Investigator: David Holztman/Alison Goate
Project Title: Identification of genetic factors associated with rate of progression
Date: December 21, 2021 at 5:18 pm
Request ID: D1004
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Investigator: Cacchione, Pamela Z.
Project Title: The Accuracy of Collateral Source Reports in Assessing Individuals for Dementia
Date: December 21, 2021 at 5:18 pm
Request ID: D0105
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Investigator: John Morris
Project Title: Cognitive reserve, brain reserve, and immediate stroke outcomes
Date: December 21, 2021 at 5:18 pm
Request ID: D1018
Aim 1: To determine whether cognitive and brain reserve factors influence immediate reaction to stroke.
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Investigator: John C. Morris
Project Title: Alzheimer mimics
Date: December 21, 2021 at 5:18 pm
Request ID: D1011
Aim 1: To increase the accuracy of diagnosis in neuropsychological and neuroimaging researches of AD
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Investigator: Ashima Agarwal MD
Project Title: Alpha-synuclein pathology in Alzheimers Dementia with Lewy bodies, Lewy body dementia, and PD
Date: December 21, 2021 at 5:18 pm
Request ID: D1003
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