The Knight ADRC has supported many investigators at Washington University and at other institutions over the years. We wish to avoid the situation where two investigators study the same research question to avoid duplication of effort and potential conflict. To determine if your topic has already been studied with our resources, please search our database. If you find that your topic or a related topic has been submitted, you may wish to contact the investigator to inquire about their findings to determine how you might proceed. You may wish to collaborate or modify your request to avoid overlap. The results below reflect requests made since online requests have been accepted. As such, not all fields will have data as certain information, such as aims, were not collected until recently. If an entry has been assigned an ID number (e.g. T1004), the full request has been submitted and is either approved, disapproved or in process. If an entry has no ID number, then it represents a submission that has not yet been reviewed. Search terms are applied across an entire requests application including variables not displayed below. A more specific, detailed search may yield better results depending upon your needs.
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Investigator: David L. Brody
Project Title: Development of an amyloid-beta oligomer assay
Date: December 21, 2021 at 5:02 pm
Request ID: T0924
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Investigator: Emma Jones
Project Title: Functional Genetic Analysis: Mechanisms of Dementia in people with Down’s syndrome
Date: December 21, 2021 at 5:02 pm
Request ID: T1001
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Investigator: Michael R Nichols
Project Title: Human Cerebrospinal Fluid as a Biomarker for Alzheimer’s Disease using an In Vitro Cellular Assay
Date: December 21, 2021 at 5:02 pm
Request ID: T1002
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Investigator: Dr David Holtzman
Project Title: The utility of the novel marker VILIP-1 in the diagnosis and prognosis of DAT
Date: December 21, 2021 at 5:02 pm
Request ID: T1003
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Investigator: Jeffery W. Kelly
Project Title: Is the Kinetic Aggregation Assay suitable for Diagnosing ALazheimer’s
Date: December 21, 2021 at 5:02 pm
Request ID: T0926
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Investigator: Jaime Grutzendler
Project Title: Embolus extravasation: a novel mechanism of cerebral microvascular recanalization
Date: December 21, 2021 at 5:02 pm
Request ID: T1012
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Investigator: David Holtzman
Project Title: Postmortem Receptor Autoradiography Study
Date: December 21, 2021 at 5:02 pm
Request ID: T1014
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Investigator: Vijay Sharma
Project Title: 99mTc-99m Labeled SPECT Agents for Imaging b-Amyloid in Alzheimer’s Disease
Date: December 21, 2021 at 5:02 pm
Request ID: T1015
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Investigator: Ryan C. Bailey
Project Title: Development of a Scalable, Pre-clinical Alzheimer’s Diagnostic Panel Based upon Silicon Photonics
Date: December 21, 2021 at 5:02 pm
Request ID: T1018
Aim 1: Validation of an emerging technology for pre-clinical AD diagnostics via multiplexed CSF proteomics
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Investigator: Huntington Potter
Project Title: Effect of immunotherapy on ACT and apoE binding to AD amyloid
Date: December 21, 2021 at 5:02 pm
Request ID: T1019
Aim 1: Determine whether anti-amyloid immunotherapy changes level of antichymotyrpsin in plaques
Aim 2: Determine whether anti-amyloid immunotherapy changes level of apoE in plaques
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