The Knight ADRC has supported many investigators at Washington University and at other institutions over the years. We wish to avoid the situation where two investigators study the same research question to avoid duplication of effort and potential conflict. To determine if your topic has already been studied with our resources, please search our database. If you find that your topic or a related topic has been submitted, you may wish to contact the investigator to inquire about their findings to determine how you might proceed. You may wish to collaborate or modify your request to avoid overlap. The results below reflect requests made since online requests have been accepted. As such, not all fields will have data as certain information, such as aims, were not collected until recently. If an entry has been assigned an ID number (e.g. T1004), the full request has been submitted and is either approved, disapproved or in process. If an entry has no ID number, then it represents a submission that has not yet been reviewed. Search terms are applied across an entire requests application including variables not displayed below. A more specific, detailed search may yield better results depending upon your needs.
Search Terms:
Investigator: Jaime Grutzendler
Project Title: Embolus extravasation: a novel mechanism of cerebral microvascular recanalization
Date: December 21, 2021 at 5:02 pm
Request ID: T1012
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Investigator: David L. Brody
Project Title: Detection of amyloid-beta oligomers
Date: December 21, 2021 at 5:02 pm
Request ID: T1006
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Investigator: Dr David Holtzman
Project Title: The utility of the novel marker VILIP-1 in the diagnosis and prognosis of DAT
Date: December 21, 2021 at 5:02 pm
Request ID: T1003
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Investigator: Sophie Allauzen
Project Title: Novartis Protein Misfolding and Aggregation Assay Validation
Date: December 21, 2021 at 5:02 pm
Request ID: T0925
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Investigator: David L. Brody
Project Title: Development of an amyloid-beta oligomer assay
Date: December 21, 2021 at 5:02 pm
Request ID: T0924
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Investigator: Gregory J Zipfel
Project Title: Cerebral Amyloid Angiopathy, Vascular Dysfunction & Ischemic Brain Injury
Date: December 21, 2021 at 5:02 pm
Request ID: T0922
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Investigator: Timothy Miller
Project Title: Examining SOD1 Protein in CSF
Date: December 21, 2021 at 5:02 pm
Request ID: T0921
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Investigator: Anja Schneider/Andre Fischer
Project Title: Genome-wide profiling of CSF miRNA expression in antecedent AD using next generatio
Date: December 21, 2021 at 5:02 pm
Request ID: T1221
Aim 1: next generation deep sequencing of CSF miRNAome
Aim 2: Identification of antecedent miRNA biomarkers to predict later AD
Aim 3: Identify longitudinal changes in CSF miRNAome accompagnying preclinical AD
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Investigator: Elliott Mufson
Project Title: CSF proNGF: a putative biomarker for Alzheimer’s disease
Date: December 21, 2021 at 5:02 pm
Request ID: T1222
Aim 1: We will test whether CSF levels of proNGF are predicitve or prodromal AD.
Aim 2: Test whether CSF proNGF levels improve the diagnostic accuracy of CSF tau/Abeta
Aim 3: Test whether CSF proNGF levels correlate with antemortem measures of cognitive decline.
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Investigator: Stephen is the PI of the UL grant; Wingo is the PI of the URC/ASCTI grant
Project Title: Autosomal Recessive Causes of Early-onset Alzheimer’s Disease
Date: December 21, 2021 at 5:02 pm
Request ID: T1223
Aim 1: Our overarching aim is to test the hypothesis that early-onset Alzheimer’s disease (AD) has autosoma
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