The Knight ADRC has supported many investigators at Washington University and at other institutions over the years. We wish to avoid the situation where two investigators study the same research question to avoid duplication of effort and potential conflict. To determine if your topic has already been studied with our resources, please search our database. If you find that your topic or a related topic has been submitted, you may wish to contact the investigator to inquire about their findings to determine how you might proceed. You may wish to collaborate or modify your request to avoid overlap. The results below reflect requests made since online requests have been accepted. As such, not all fields will have data as certain information, such as aims, were not collected until recently. If an entry has been assigned an ID number (e.g. T1004), the full request has been submitted and is either approved, disapproved or in process. If an entry has no ID number, then it represents a submission that has not yet been reviewed. Search terms are applied across an entire requests application including variables not displayed below. A more specific, detailed search may yield better results depending upon your needs.
Search Terms:
Investigator: Dr. Denise Head
Project Title: Effects of the BDNF polymorphism and exercise on brain structure, AD biomarkers and cognition.
Date: December 21, 2021 at 5:18 pm
Request ID: D1102
Aim 1: examine the effects of the BDNF polymorphism on brain, cognition, and AD biomarkers
Aim 2: examine interactions between the BDNF polymorphism and exercise
Aim 3: examine interactions between the BDNF polymorphism and age
Aim 4: examine interactions between the APOE and BDNF polymorphisms
Investigator: Luigi Maccotta
Project Title: Functional Connectivity in Epilepsy
Date: December 21, 2021 at 5:18 pm
Request ID: D1103
Aim 1: To characterize changes in local and long-range functional connections in temporal lobe epilepsy
Aim 2: To characterize connectivity changes in TLE patients with grossly normal brain anatomy
Aim 3:
Aim 4:
Investigator: Dr. John Morris
Project Title: Age of Onset Disparities among first degree relatives
Date: December 21, 2021 at 5:18 pm
Request ID: D1104
Aim 1: To determine the causes for AOO disparities among first degree relatives
Aim 2:
Aim 3:
Aim 4:
Investigator: Mintun, Mark
Project Title: A Pilot Study of C-11 PIB Brain Uptake and Binding
Date: December 21, 2021 at 5:18 pm
Request ID: D0406
Aim 1:
Aim 2:
Aim 3:
Aim 4:
Investigator: Brian Gordon
Project Title: The Influence of Brain Structure on Prospective Memory
Date: December 21, 2021 at 5:18 pm
Request ID: D1019
Aim 1: Explore the relationship of medial temporal lobe volume and focal prospective memory
Aim 2: Explore the relationship of prefrontal structures and non-focal prospective memory
Aim 3: Investigate the influence of disease and genetic status on the link between behavior and anatomy
Aim 4:
Investigator: David Holztman/Alison Goate
Project Title: Identification of genetic factors associated with rate of progression
Date: December 21, 2021 at 5:18 pm
Request ID: D1004
Aim 1:
Aim 2:
Aim 3:
Aim 4:
Investigator: Denise Head
Project Title: Exercise, Aging, and Functional Connectivity
Date: December 21, 2021 at 5:18 pm
Request ID: D1013
Aim 1:
Aim 2:
Aim 3:
Aim 4:
Investigator: Cacchione, Pamela Z.
Project Title: The Accuracy of Collateral Source Reports in Assessing Individuals for Dementia
Date: December 21, 2021 at 5:18 pm
Request ID: D0105
Aim 1:
Aim 2:
Aim 3:
Aim 4:
Investigator: John Morris
Project Title: Cognitive reserve, brain reserve, and immediate stroke outcomes
Date: December 21, 2021 at 5:18 pm
Request ID: D1018
Aim 1: To determine whether cognitive and brain reserve factors influence immediate reaction to stroke.
Aim 2:
Aim 3:
Aim 4:
Investigator: John C. Morris
Project Title: Alzheimer mimics
Date: December 21, 2021 at 5:18 pm
Request ID: D1011
Aim 1: To increase the accuracy of diagnosis in neuropsychological and neuroimaging researches of AD
Aim 2:
Aim 3:
Aim 4: