The Knight ADRC has supported many investigators at Washington University and at other institutions over the years. We wish to avoid the situation where two investigators study the same research question to avoid duplication of effort and potential conflict. To determine if your topic has already been studied with our resources, please search our database. If you find that your topic or a related topic has been submitted, you may wish to contact the investigator to inquire about their findings to determine how you might proceed. You may wish to collaborate or modify your request to avoid overlap. The results below reflect requests made since online requests have been accepted. As such, not all fields will have data as certain information, such as aims, were not collected until recently. If an entry has been assigned an ID number (e.g. T1004), the full request has been submitted and is either approved, disapproved or in process. If an entry has no ID number, then it represents a submission that has not yet been reviewed. Search terms are applied across an entire requests application including variables not displayed below. A more specific, detailed search may yield better results depending upon your needs.
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Investigator: Powers, William
Project Title: CCCVD Sharing of Sequential Scans
Date: [153]
Request ID: D0115
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Investigator: Storandt, Martha
Project Title: The Effects of Age and Dementia on the Boston Naming Test (BNT)
Date: [153]
Request ID: D0106
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Investigator: Cacchione, Pamela Z.
Project Title: The Accuracy of Collateral Source Reports in Assessing Individuals for Dementia
Date: [153]
Request ID: D0105
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Investigator: Csernansky, John G.
Project Title: Comparison of automatic analysis of hippocampal structure methods
Date: [153]
Request ID: D0101
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Investigator: Timothy M. Miller
Project Title: Understanding elevated SOD1 in CSF from AD patients
Date: [153]
Request ID: D1024
Aim 1: Correlate SOD1 levels in CSF with other ADRC measurements on same patients
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Investigator: Jingqin Luo, Chengjie Xiong, Ming an Yang
Project Title: Random change point modele for longitudinal cognitive dementia
Date: [153]
Request ID: D1023
Aim 1: It is hypothesized that a change point exists
Aim 2: Alzheimer’s disease patients will experience accerlerated dementa after the change point
Aim 3: We will identify the change point in visuospatial score and logical memory jointly
Aim 4: The relationship between the two change points helps clinical utilization of the two change points

Investigator: Mingan Yang, Chengjie Xiong
Project Title: Biostat modelling for Alzheimer’s disease
Date: [153]
Request ID: D1022
Aim 1: Develop flexible statistical methodology to study issues of Alzeheimer disease
Aim 2: To improve the current methods, to address some issues the medical researchers are interested in
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Investigator: Halley Hindman
Project Title: Physical Activity, Cognition, and Regional Brain Volumes
Date: [153]
Request ID: D1021
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Investigator: Dr. James Brewer
Project Title: Imaging studies of brain structure and function in aging and dementia
Date: [153]
Request ID: D1020
Aim 1: Examine the relationship between brain atrophy and functional decline in aging and dementia
Aim 2: Examine the relationship between brain atrophy and cellular biomarkers in aging and dementia
Aim 3: Examine the relationship between brain atrophy and genetic markers in aging and dementia
Aim 4: Examine the relationship between brain atrophy and intracranial amyloid load in aging and dementia

Investigator: Brian Gordon
Project Title: The Influence of Brain Structure on Prospective Memory
Date: [153]
Request ID: D1019
Aim 1: Explore the relationship of medial temporal lobe volume and focal prospective memory
Aim 2: Explore the relationship of prefrontal structures and non-focal prospective memory
Aim 3: Investigate the influence of disease and genetic status on the link between behavior and anatomy
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