Researcher Publication Search

Name: Monique Williams
Year: 2010

Reference:

Williams MM, Scharff DP, Mathews KJ, Hoffsuemmer JS, Jackson P, Morris JC, Edwards DF. Barriers and facilitators of African American participation in Alzheimer’s disease biomarker research. Alzheimer Disease & Associated Disorders 2010; 24 Suppl:S24-S29. PMCID:PMC2939138

Name: Robert Mach
Year: 2010

Reference:

Zeng C, Pan F, Jones LA, Lim MM, Griffin EA, Sheline YI, Mintun MA, Holtzman DM, Mach RH. Evaluation of 5-ethynyl-2’-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system. Brain Research 2010; 1319: 21-32. PMID: 20064490.

Name: Raphael Kopan
Year: 2010

Reference:

Zhao G, Liu Z, Ilagan MX and Kopan R: γ-Secretase composed of PS1/Pen2/Aph1a can cleave Notch and amyloid precursor protein in the absence of nicastrin. J Neurosci (2010) 30:1648-1656. PMC2853942

Name: Raphael Kopan
Year: 2010

Reference:

Zhao G, Liu Z, Ilagan MX and Kopan R: γ-Secretase composed of PS1/Pen2/Aph1a can cleave Notch and amyloid precursor protein in the absence of nicastrin. J Neurosci (2010) 30:1648-1656. PMC2853942

Name: Randall Bateman
Year: 2009

Reference:

Bateman RJ, Siemers ER, Mawuenyega KG, Wen G, Browning KR, Sigurdson WC, Yarasheski KE, Friedrich SW, Demattos RB, May PC, Paul SM, Holtzman DM. A Gamma-Secretase Inhibitor Decreases Amyloid-Beta Production in the Central Nervous System. Ann Neurol. 2009 Jul;66(1):48-54. PMID: 19360898

Name: Anne Fagan
Year: 2009

Reference:

Britschgi M, Olin CE, Johns HT, Takeda-Uchimura Y, LeMieux MC, Rufibach K, Rajadas J, Zhang H, Tomooka B, Robinson WH, Clark CM, Fagan AM, Galasko DR, Holtzman DM, Jutel M, Kaye JA, Lemere CA, Leszek J, Li G, Peskind ER, Quinn JF, Yesavage JA, Ghiso JA, Wyss-Coray T. Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer’s disease. Proceedings of the National Academy of Science USA, 2009; 106:12145-50. PMCID: PMC2715538

Name: Anne Fagan
Year: 2009

Reference:

Cairns NJ, Ikonomovic MD, Benzinger T, Storandt M, Fagan AM, Shah AR, Taylor-Reinwald L, Carter D, Felton A, Holtzman DM, Mintun MA, Klunk WE, Morris JC. Absence of Pittsburgh Compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease. Archives of Neurology, 2009; 66:1557-62. PMCID: PMC2796200

Name: Robert Mach
Year: 2009

Reference:

Chu W, Rothfuss J, Chu Y, Zhou D, Mach RH. Synthesis and In Vitro Evaluation of Sulfonamide Isatin Michael Acceptors as Small Molecule Inhibitors of Caspase-6. J. Med. Chem. 2009; 52: 2188-2191. PMID: 19326941

Name: Anne Fagan
Year: 2009

Reference:

Clifford DB, Fagan AM, Holtzman DM, Morris JC, Teshome M, Shah AR, Kauwe JS. CSF biomarkers of Alzheimer disease in HIV-associated neurologic disease. Neurology, 2009; 73:1982-87. PMCID: PMC2790234

Name: Anne Fagan
Year: 2009

Reference:

Duchek JM, Balota DA, Tse CS, Holtzman DM, Fagan AM, Goate AM. The utility of intraindividual variability in selective attention tasks as an early marker for Alzheimer’s disease. Neuropsychology, 2009; 23:746-58. PMCID: PMC2779520

Name: Anne Fagan
Year: 2009

Reference:

Fagan AM, Head, D, Shah AR, Marcus D, Mintun M, Morris JC, Holtzman DM. Decreased cerebrospinal fluid Aβ42 correlates with brain atrophy in cognitively normal elderly. Annals of Neurology, 2009, 65:176-183. PMCID: PMC2763631

Name: Anne Fagan
Year: 2009

Reference:

Fagan AM, Mintun MA, Shah AR, Aldea P, Roe CM, Mach RH, Marcus D, Morris JC, Holtzman DM. Cerebrospinal fluid tau and ptau181 increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer’s disease. EMBO Molecular Medicine, 2009; 1:371-80. PMCID: PMC2806678

Name: Raphael Kopan
Year: 2009

Reference:

Hass MR, Sato C, Kopan R, Zhao G. Presenilin: RIP and beyond. Semin Cell Dev Biol. 2009, 20:201-210.PMCID: PMC2693421

Name: Anne Fagan
Year: 2009

Reference:

Hinrichs AL, Mintun MA, Head D, Fagan AM, Holtzman DM, Morris JC, Goate AM. Cortical binding of Pittsburgh Compound B, an endophenotype for genetic studies of Alzheimer’s disease. Biological Psychiatry, 2009; 67:581-583. PMCID: PMC2866645

Name: Randall Bateman
Year: 2009

Reference:

Kang JE, Lim MM, Bateman RJ, Lee JJ, Smyth LP, Cirrito JR, Fujiki N, Nishino S, Holtzman DM. Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle. Science. 2009 Nov 13;326(5955):1005-7. Epub 2009 Sep 24. PMID: 19779148

Name: Anne Fagan
Year: 2009

Reference:

Kauwe JS, Wang J, Mayo K, Morris JC, Fagan AM, Holtzman DM, Goate AM. Alzheimer’s disease risk variants show association with cerebrospinal fluid amyloid beta. Neurogenetics. 2009; 10:13-7. PMCID: PMC2726757

Name: Anne Fagan
Year: 2009

Reference:

Morris JC, Roe CM, Grant EA, Head D, Storandt M, Goate AM, Fagan AM, Holtzman DM, Mintun MA. Pittsburgh Compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer’s disease, Archives of Neurology, 2009; 66:1469-75. PMCID: PMC2798814

Name: Anne Fagan
Year: 2009

Reference:

Okereke OI, Xia W, Irizarry MC, Sun X, Qiu WQ, Fagan AM, Mehta PD, Hyman BT, Selkoe DJ, Grodstein F. Performance characteristics of plasma amyloid-beta 40 and 42 assays. Journal of Alzheimers Disease, 2009; 16:277-85. PMCID: PMC2737811

Name: Anne Fagan
Year: 2009

Reference:

Perrin RJ, Fagan AM, Holtzman DM. Multimodal techniques for diagnosis and prognosis of Alzheimer’s disease, Nature, 2009; 461:916-22. PMCID: PMC2810658

Name: Anne Fagan
Year: 2009

Reference:

Snider BJ, Fagan AM, Roe CM, Shah AR, Grant EA, Xiong C, Morris JC, Holtzman DM. Cerebrospinal fluid biomarkers and rate of cognitive decline in very mild dementia of the Alzheimer’s type. Archives of Neurology, 2009; 66:638-45. PMCID: PMC2759394

Name: Randall Bateman
Year: 2009

Reference:

Wildsmith KR, Han B, Bateman RJ. Method for the simultaneous quantitation of apolipoprotein E isoforms using tandem mass spectrometry. Anal Biochem. 2009 Dec 1;395(1):116-8. Epub 2009 Aug 3. PMID: 19653990

Name: Anne Fagan
Year: 2008

Reference:

Craig-Schapiro R, Fagan AM, Holtzman DM. Biomarkers of Alzheimer’s disease, Neurobiology of Disease, 2008; 35:128-140. PMCID: PMC2747727

Name: Randall Bateman
Year: 2008

Reference:

Elbert DL, Mawuenyega KG, Scott EA, Wildsmith KR, Bateman RJ. Stable isotope labeling tandem mass spectrometry (SILT): integration with peptide identification and extension to data-dependent scans. J Proteome Res. 2008 Oct;7(10):4546-56. Epub 2008 Sep 6. PMID: 18774841

Name: Anne Fagan
Year: 2008

Reference:

Kauwe JS, Cruchaga C, Mayo K, Fenoglio C, Bertelsen S, Nowotny P, Galimberti D, Scarpini E, Morris JC, Fagan AM, Holtzman DM, Goate AM. Variation in MAPT is associated with cerebrospinal fluid tau levels in the presence of amyloid-beta deposition. Proceedings of the National Academy of Science. USA, 2008; 105:8050-4. PMCID: PMC2430357

Name: Anne Fagan
Year: 2008

Reference:

Lemere CA, Oh J, Stanish HA, Peng Y, Pepivani I, Fagan AM, Yamaguchi H, Westmoreland SV, Mansfield KG. Cerebral amyloid-beta protein accumulation with aging in cotton-top tamarins: a model of early Alzheimer’s disease? Rejuvenation Research, 2008; 11:321-32 Accepted prior to April 7, 2008