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Name: Randall Bateman
Year: 2007

Reference:

Bateman RJ, Munsell LY, Chen X, Holtzman DM, Yarasheski KE. Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates. J Am Soc Mass Spectrom. 2007 Jun;18(6):997-1006. Epub 2007 Feb 22. PMID: 17383190

Name: Randall Bateman
Year: 2007

Reference:

Bateman RJ, Munsell LY, Morris JC, Swarm R, Yarasheski KE, Holtzman DM. Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo. Nat Med. 2006 Jul;12(7):856-61. Epub 2006 Jun 25. PMID: 16799555

Name: Randall Bateman
Year: 2007

Reference:

Bateman RJ, Wen G, Morris JC, Holtzman DM. Fluctuations of CSF amyloid-beta levels: implications for a diagnostic and therapeutic biomarker. Neurology. 2007 Feb 27;68(9):666-9. PMID: 17325273

Name: Anne Fagan
Year: 2007

Reference:

Hu Y, Hosseini A, Kauwe JSK, Gross J, Cairns NJ, Goate AM, Fagan AM, Townsend RR, Holtzman DM Identification and validation of novel CSF biomarkers for early stages of Alzheimer’s disease. Proteomics – Clinical Applications, 2007; 1:1374-1384.

Name: Anne Fagan
Year: 2007

Reference:

Kauwe JS, Jacquart S, Chakraverty S, Wang J, Mayo K, Fagan AM, Holtzman DM, Morris JC, Goate AM. Extreme Cerebrospinal Fluid Amyloid Beta Levels Identify Family with Late-Onset Alzheimer’s Disease Presenilin 1 Mutation. Annals of Neurology 2007; 61(5):446-53.

Name: Anne Fagan
Year: 2007

Reference:

Kauwe JSK, Jacquart S, Chakraverty S, Wang J, Mayo K, Mintun M, Fagan AM, Holtzman DM, Morris JC, Goate AM. Use of cerebrospinal fluid amyloid-β levels as an endophenotype identifies a PSEN1 mutation causing Alzheimer’s disease in a late-onset family. Annals of Neurology, 2007; 61(5):446-53.

Name: Anne Fagan
Year: 2007

Reference:

Kauwe JSK, Jacquart S, Chakraverty S, Wang J, Mayo K, Mintun M, Fagan AM, Holtzman DM, Morris JC, Goate AM. Use of cerebrospinal fluid amyloid-β levels as an endophenotype identifies a PSEN1 mutation causing Alzheimer’s disease in a late-onset family. Annals of Neurology, 2007; 61(5):446-53.

Name: Raphael Kopan
Year: 2007

Reference:

Khandelwal A, Chandu D, Roe CM, Kopan R and Quatrano RS: Moonlighting activity of presenilin in plants is independent of γ-secretase and evolutionarily conserved. Proc Natl Acad Sci USA (2007) 104:13337-13342. PMC1948938

Name: Raphael Kopan
Year: 2007

Reference:

Khandelwal, A., Chandu, D., Roe, C.M., Kopan, R., and Quatrano, R.S. (2007). Moonlighting activity of presenilin in plants is independent of “-secretase and evolutionarily conserved. Proc Natl Acad Sci U S A 104, 13337-13342.

Name: Anne Fagan
Year: 2007

Reference:

Wahrle SE, Shah AR, Fagan AM, Smemo S, Kauwe JSK, Grupe A, Hinrichs A, Mayo K, Jiang H, Thal LJ, Goate AM, Holtzman DM. Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1 polymorphisms. Molecular Neurodegeneration, 2007; 12;2:7.

Name: Anne Fagan
Year: 2006

Reference:

Csernansky JG, Dong H, Fagan AM, Wang L, Xiong C, Holtzman DM, and Morris JC. Plasma cortisol and progression of dementia in subjects with Alzheimer-type dementia, American Journal of Psychiatry, 2006; 163: 2164-9.

Name: Anne Fagan
Year: 2006

Reference:

Fagan AM, Mintun MA, Mach RH, Lee S-Y, Dence CS, Shah AR, LaRossa G, Spinner ML, Klunk WE, Mathis CA, DeKosky ST, Morris JC, Holtzman DM Inverse relation between in vivo amyloid imaging load and CSF A42 in humans, Annals of Neurology, 2006; 59:512-519.

Name: Jeffrey Zacks
Year: 2006

Reference:

Zacks, J. M., Speer, N. K., Vettel, J. M., & Jacoby, L. L. (2006). Event understanding and memory in healthy aging and dementia of the Alzheimer type. Psychology & Aging, 21, 466-482. PMID: 16953710.

Name: Anne Fagan
Year: 2005

Reference:

Fagan AM, Csernansky CA, Morris JC, Holtzman DM. The search for antecedent biomarkers of Alzheimer’s disease, Journal of Alzheimer Disease, 2005; 8:347-358.

Name: Anne Fagan
Year: 2005

Reference:

Hu Y, Townsend R, Fagan AM, Holtzman DM. Comparative proteomics analysis of intra- and inter-individual variation in human cerebrospinal fluid, Molecular and Cellular Proteomics, 2005; 4:2000-2009.

Name: Virginia Buckles
Year: 2004

Reference:

31. Cacchione PZ, Powlishta KK, Grant EA, Buckles VD, Morris JC. Collateral source reports in very mild to mild dementia of the Alzheimer type. In: Vellas B, Fitten LJ, Winblad B, Feldman H, Grundman M, Giacobini E, Kurz A. (Eds) Research and Practice in Alzheimer Disease (vol 9). Paris France: Serdi publishers, 2004, pp. 13-20

Name: Anne Fagan
Year: 2003

Reference:

Han X, Fagan AM, Cheng H, Morris JC, Xiong C and Holtzman DM. Cerebrospinal fluid sulfatide is decreased in subjects with incipient dementia, Annals of Neurology, 2003; 54:115-118

Name: Anne Fagan
Year: 2000

Reference:

Fagan AM, Holtzman DM. Astrocyte lipoproteins, effects of apoE on neuronal function, and role of apoE in amyloid-Beta deposition in vivo, Microscopy Research and Technique, 2000; 50:297-304.

Name: Anne Fagan
Year: 2000

Reference:

Fagan AM, Younkin LH, Morris JC, Fryer JD, Cole TG, Younkin SG, Holtzman DM. Differences in the A40/A42 ratio associated with CSF lipoproteins as a function of apolipoprotein E genotype. Annals of Neurology, 2000; 48:201-210.