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Name: Brian Carpenter
Year: 2010

Reference:

Sakai EY, Carpenter BD. Linguistic features of power dynamics in triadic dementia diagnostic conversations. Patient Education and Counseling. In Press. 10.1016/j.pec.2010.09.020

Name: Yvette Sheline
Year: 2010

Reference:

Sheline YI, Morris JC, Price JL, Yan Z, Liu C, Dixit S, Benzinger T, D’Angelo G, Snyder AZ, Fagan A, Goate, A. APOE4 Allele Disrupts Resting State fMRI Connectivity in the Absence of Amyloid Plaques or Decreased AB42. J Neurosci,Dec 2010 15;30(50):17035-40. PMCID:PMC3023180

Name: Alison Goate
Year: 2010

Reference:

Sheline YI, Morris JC, Snyder AZ, Price JL, Yan Z, D’Angelo G, Liu C, Dixit S, Benzinger T, Fagan A, Goate A, Mintun MA. APOE4 allele disrupts resting state fMRI connectivity in the absence of amyloid plaques or decreased CSF Aβ42. J Neurosci. 2010; 30(50):17035-40.

Name: Anne Fagan
Year: 2010

Reference:

Sheline YI, Morris JC, Snyder AZ, Price JL, Yan Z, D’Angelo G, Liu C, Dixit S, Benzinger T, Fagan A, Goate A, Mintun MA. APOE4 allele disrupts resting state fMRI connectivity in the absence of amyloid plaques or decreased CSF Aβ42. Journal of Neuroscience, 2010; 30:17035-40. PMID: 21159973

Name: Yvette Sheline
Year: 2010

Reference:

Sheline YI, Raichle ME, Snyder AZ, Morris JC, Head D, Wang S, Mintun MA. Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly. Biol Psychiatry 2010; 15:584-7. PMCID: PMC2829379.

Name: Raphael Kopan
Year: 2010

Reference:

Tong, Y., H. Yamaguchi, E. Giaime, S. Boyle, R. Kopan, R.J. Kelleher, 3rd, and J. Shen: Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice. Proc Natl Acad Sci USA (2010) 107:9879-9884. PMC2906862

Name: David Balota
Year: 2010

Reference:

Tse CS, Balota DA, Roediger HL. The benefits and costs of repeated testing on the learning of face-name pairs in healthy older adults. Psychology & Aging 2010; 25: 833-845. PMCID: 2990807.

Name: Monique Williams
Year: 2010

Reference:

Williams MM, Meisel MM, Williams J, Morris JC. An interdisciplinary outreach model of African American recruitment for Alzheimer’s Disease research, The Gerontologist 2010; doi: 10.1093/geront/gnq098

Name: Monique Williams
Year: 2010

Reference:

Williams MM, Scharff DP, Mathews KJ, Hoffsuemmer JS, Jackson P, Morris JC, Edwards DF. Barriers and facilitators of African American participation in Alzheimer’s disease biomarker research. Alzheimer Disease & Associated Disorders 2010; 24 Suppl:S24-S29. PMCID:PMC2939138

Name: Robert Mach
Year: 2010

Reference:

Zeng C, Pan F, Jones LA, Lim MM, Griffin EA, Sheline YI, Mintun MA, Holtzman DM, Mach RH. Evaluation of 5-ethynyl-2’-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system. Brain Research 2010; 1319: 21-32. PMID: 20064490.

Name: Raphael Kopan
Year: 2010

Reference:

Zhao G, Liu Z, Ilagan MX and Kopan R: γ-Secretase composed of PS1/Pen2/Aph1a can cleave Notch and amyloid precursor protein in the absence of nicastrin. J Neurosci (2010) 30:1648-1656. PMC2853942

Name: Raphael Kopan
Year: 2010

Reference:

Zhao G, Liu Z, Ilagan MX and Kopan R: γ-Secretase composed of PS1/Pen2/Aph1a can cleave Notch and amyloid precursor protein in the absence of nicastrin. J Neurosci (2010) 30:1648-1656. PMC2853942

Name: Randall Bateman
Year: 2009

Reference:

Bateman RJ, Siemers ER, Mawuenyega KG, Wen G, Browning KR, Sigurdson WC, Yarasheski KE, Friedrich SW, Demattos RB, May PC, Paul SM, Holtzman DM. A Gamma-Secretase Inhibitor Decreases Amyloid-Beta Production in the Central Nervous System. Ann Neurol. 2009 Jul;66(1):48-54. PMID: 19360898

Name: Anne Fagan
Year: 2009

Reference:

Britschgi M, Olin CE, Johns HT, Takeda-Uchimura Y, LeMieux MC, Rufibach K, Rajadas J, Zhang H, Tomooka B, Robinson WH, Clark CM, Fagan AM, Galasko DR, Holtzman DM, Jutel M, Kaye JA, Lemere CA, Leszek J, Li G, Peskind ER, Quinn JF, Yesavage JA, Ghiso JA, Wyss-Coray T. Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer’s disease. Proceedings of the National Academy of Science USA, 2009; 106:12145-50. PMCID: PMC2715538

Name: Anne Fagan
Year: 2009

Reference:

Cairns NJ, Ikonomovic MD, Benzinger T, Storandt M, Fagan AM, Shah AR, Taylor-Reinwald L, Carter D, Felton A, Holtzman DM, Mintun MA, Klunk WE, Morris JC. Absence of Pittsburgh Compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease. Archives of Neurology, 2009; 66:1557-62. PMCID: PMC2796200

Name: Robert Mach
Year: 2009

Reference:

Chu W, Rothfuss J, Chu Y, Zhou D, Mach RH. Synthesis and In Vitro Evaluation of Sulfonamide Isatin Michael Acceptors as Small Molecule Inhibitors of Caspase-6. J. Med. Chem. 2009; 52: 2188-2191. PMID: 19326941

Name: Anne Fagan
Year: 2009

Reference:

Clifford DB, Fagan AM, Holtzman DM, Morris JC, Teshome M, Shah AR, Kauwe JS. CSF biomarkers of Alzheimer disease in HIV-associated neurologic disease. Neurology, 2009; 73:1982-87. PMCID: PMC2790234

Name: Anne Fagan
Year: 2009

Reference:

Duchek JM, Balota DA, Tse CS, Holtzman DM, Fagan AM, Goate AM. The utility of intraindividual variability in selective attention tasks as an early marker for Alzheimer’s disease. Neuropsychology, 2009; 23:746-58. PMCID: PMC2779520

Name: Anne Fagan
Year: 2009

Reference:

Fagan AM, Head, D, Shah AR, Marcus D, Mintun M, Morris JC, Holtzman DM. Decreased cerebrospinal fluid Aβ42 correlates with brain atrophy in cognitively normal elderly. Annals of Neurology, 2009, 65:176-183. PMCID: PMC2763631

Name: Anne Fagan
Year: 2009

Reference:

Fagan AM, Mintun MA, Shah AR, Aldea P, Roe CM, Mach RH, Marcus D, Morris JC, Holtzman DM. Cerebrospinal fluid tau and ptau181 increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer’s disease. EMBO Molecular Medicine, 2009; 1:371-80. PMCID: PMC2806678

Name: Raphael Kopan
Year: 2009

Reference:

Hass MR, Sato C, Kopan R, Zhao G. Presenilin: RIP and beyond. Semin Cell Dev Biol. 2009, 20:201-210.PMCID: PMC2693421

Name: Anne Fagan
Year: 2009

Reference:

Hinrichs AL, Mintun MA, Head D, Fagan AM, Holtzman DM, Morris JC, Goate AM. Cortical binding of Pittsburgh Compound B, an endophenotype for genetic studies of Alzheimer’s disease. Biological Psychiatry, 2009; 67:581-583. PMCID: PMC2866645

Name: Randall Bateman
Year: 2009

Reference:

Kang JE, Lim MM, Bateman RJ, Lee JJ, Smyth LP, Cirrito JR, Fujiki N, Nishino S, Holtzman DM. Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle. Science. 2009 Nov 13;326(5955):1005-7. Epub 2009 Sep 24. PMID: 19779148

Name: Anne Fagan
Year: 2009

Reference:

Kauwe JS, Wang J, Mayo K, Morris JC, Fagan AM, Holtzman DM, Goate AM. Alzheimer’s disease risk variants show association with cerebrospinal fluid amyloid beta. Neurogenetics. 2009; 10:13-7. PMCID: PMC2726757

Name: Anne Fagan
Year: 2009

Reference:

Morris JC, Roe CM, Grant EA, Head D, Storandt M, Goate AM, Fagan AM, Holtzman DM, Mintun MA. Pittsburgh Compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer’s disease, Archives of Neurology, 2009; 66:1469-75. PMCID: PMC2798814