Researcher Publication Search | Knight Alzheimer Disease Research Center

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Name: Suzanne Schindler
Year: 2025

Reference:

Ali M, Timsina J, Western D, Liu M, Beric A, Budde J, Do A, Heo G, Wang L, Gentsch J, Schindler SE, Morris JC, Holtzman DM, Ruiz A, Alvarez I, Aguilar M, Pastor P, Rutledge J, Oh H, Wilson EN, Guen YL, Khalid RR; Knight Alzheimer Disease Research Center (Knight ADRC); Alzheimer Disease Neuroimaging Initiative (ADNI); Fundació ACE Alzheimer Center Barcelona (FACE); Barcelona-1; Stanford Alzheimer Disease Research Center (Stanford ADRC); Robins C, Pulford DJ, Tarawneh R, Ibanez L, Wyss-Coray T, Sung YJ, Cruchaga C. Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures across the Alzheimer disease continuum. Neuron. 2025 Mar 12:S0896-6273(25)00132-1. doi: 10.1016/j.neuron.2025.02.014. Epub ahead of print. PMID: 40088886.

Name: Suzanne Schindler
Year: 2025

Reference:

Horie K, Salvadó G, Koppisetti RK, Janelidze S, Barthélemy NR, He Y, Sato C, Gordon BA, Jiang H, Benzinger TLS, Stomrud E, Holtzman DM, Mattsson-Carlgren N, Morris JC, Palmqvist S, Ossenkoppele R, Schindler SE, Hansson O, Bateman RJ. Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease. Nat Med. 2025 Mar 31. PMID: 40164726.

Name: Suzanne Schindler
Year: 2025

Reference:

Leuzy A, Bollack A, Pellegrino D, Teunissen CE, La Joie R, Rabinovici GD, Franzmeier N, Johnson K, Barkhof F, Shaw LM, Arkhipenko A, Schindler SE, Honig LS, Moscoso Rial A, Schöll M, Zetterberg H, Blennow K, Hansson O, Farrar G. Considerations in the clinical use of amyloid PET and CSF biomarkers for Alzheimer’s disease. Alzheimers Dement. 2025 Mar;21(3):e14528. doi: 10.1002/alz.14528. PMID: 40042435; PMCID: PMC11881640.

Name: Suzanne Schindler
Year: 2025

Reference:

Ossenkoppele R, Salvadó G, Janelidze S, Pichet Binette A, Bali D, Karlsson L, Palmqvist S, Mattsson-Carlgren N, Stomrud E, Therriault J, Rahmouni N, Rosa-Neto P, Coomans EM, van de Giessen E, van der Flier WM, Teunissen CE, Jonaitis EM, Johnson SC, Villeneuve S; PREVENT-AD Research Group; Benzinger TLS, Schindler SE, Bateman RJ, Doecke JD, Doré V, Feizpour A, Masters CL, Rowe C, Wiste HJ, Petersen RC, Jack CR Jr, Hansson O. Plasma p-tau217 and tau-PET predict future cognitive decline among cognitively unimpaired individuals: implications for clinical trials. Nat Aging. 2025 Mar 28. doi: 10.1038/s43587-025-00835-z. Epub ahead of print. PMID: 40155777.

Name: Suzanne Schindler
Year: 2025

Reference:

Rabinovici GD, Selkoe DJ, Schindler SE, Aisen P, Apostolova LG, Atri A, Greenberg SM, Hendrix SB, Petersen RC, Weiner M, Salloway S, Cummings J. Donanemab: Appropriate use recommendations. J Prev Alzheimers Dis. 2025 Mar 27:100150. doi: 10.1016/j.tjpad.2025.100150. Epub ahead of print. PMID: 40155270.

Name: Emily Willroth
Year: 2025

Reference:

Rule PD, Trammell VL, Hill PL, Pearlstein JG, Willroth EC. A scoping review and synthesis of the literature on the relation between mobility impairment and cognitive impairment. Disabil Rehabil. 2025 Jan 13:1-10. doi: 10.1080/09638288.2024.2449392. Epub ahead of print. PMID: 39804027.

Name: Suzanne Schindler
Year: 2025

Reference:

Schindler SE, Musiek ES, Morris JC. Anti-amyloid treatments: Why we think they are worth it. Alzheimers Dement (N Y). 2025 Feb 24;11(1):e70055. doi: 10.1002/trc2.70055. PMID: 39995599; PMCID: PMC11848731.

Name: Suzanne Schindler
Year: 2025

Reference:

VandeVrede L, Schindler SE. Clinical use of biomarkers in the era of Alzheimer’s disease treatments. Alzheimers Dement. 2025 Jan;21(1):e14201. doi: 10.1002/alz.14201. Epub 2024 Dec 30. PMID: 39740074; PMCID: PMC11775455.

Name: Zongtao Tom Lin
Year: 2024

Reference:

1. Lin*, Xie, Gongora, Liu, Zahn, Palai, Ramirez, Searfoss, Vitorino, Dann, Zhao, Han, MacTaggart, Lan, Fu, Greenberg, Zhang, Lavine, Greenberg, Lv, Kashina, Garcia*. An Unbiased Proteomic Platform for Activity-based Arginylation Profiling. 2024. bioRxiv. Nature Chem. Bio. (under review). PMID: 38854050
2. Xie*, Brás-Costa, Lin, Garcia*.Mass spectrometry analysis of nucleic acid modifications: from beginning to future. Mass Spectrometry Reviews. 2024. (under review).

Name: Suzanne Schindler
Year: 2024

Reference:

Buckley RF, Schindler SE. Lower Accuracy Alzheimer Disease Blood Tests Will Never Be “Ready for Prime Time”. Neurology. 2024 Apr 23;102(8):e209295. doi: 10.1212/WNL.0000000000209295. Epub 2024 Mar 25. PMID: 38527244.

Name: Suzanne Schindler
Year: 2024

Reference:

Delvenne A, Gobom J, Schindler SE, Kate MT, Reus LM, Dobricic V, Tijms BM, Benzinger TLS, Cruchaga C, Teunissen CE, Ramakers I, Martinez-Lage P, Tainta M, Vandenberghe R, Schaeverbeke J, Engelborghs S, Roeck E, Popp J, Peyratout G, Tsolaki M, Freund-Levi Y, Lovestone S, Streffer J, Barkhof F, Bertram L, Blennow K, Zetterberg H, Visser PJ, Vos SJB. CSF proteomic profiles of neurodegeneration biomarkers in Alzheimer’s disease. Alzheimers Dement. 2024 Jul 6. PMID: 38970402.

Name: Suzanne Schindler
Year: 2024

Reference:

Name: Suzanne Schindler
Year: 2024

Reference:

Frank B, Walsh M, Hurley L, Groh J, Blennow K, Zetterberg H, Tripodis Y, Budson AE, O’Connor MK, Martin B, Weller J, McKee A, Qiu W, Stein TD, Stern RA, Mez J, Henson R, Long J, Aschenbrenner AJ, Babulal GM, Morris JC, Schindler S, Alosco ML. Cognition Mediates the Association Between Cerebrospinal Fluid Biomarkers of Amyloid and P-Tau and Neuropsychiatric Symptoms. J Alzheimers Dis. 2024;100(3):1055-1073. doi: 10.3233/JAD-240125. PMID: 38995786.

Name: Suzanne Schindler
Year: 2024

Reference:

Janelidze S, Barthélemy NR, Salvadó G, Schindler SE, Palmqvist S, Mattsson-Carlgren N, Braunstein JB, Ovod V, Bollinger JG, He Y, Li Y, Raji CA, Morris JC, Holtzman DM, Ashton NJ, Blennow K, Stomrud E, Bateman RJ, Hansson O. Plasma Phosphorylated Tau 217 and Aβ42/40 to Predict Early Brain Aβ Accumulation in People Without Cognitive Impairment. JAMA Neurol. 2024 Sep 1;81(9):947-957. doi: 10.1001/jamaneurol.2024.2619. PMID: 39068669; PMCID: PMC11284634.

Name: Suzanne Schindler
Year: 2024

Reference:

Name: Susan Stark
Year: 2024

Reference:

Keleman AA, Bollinger RM, Rodakowski J, Chang CH, Kehrer-Dunlap AL, Ances BM, Stark SL. Exploring the Remote Administration of a Performance-Based Functional Assessment. J Appl Gerontol 2024; 7334648241292968. doi: 10.1177/07334648241292968. Epub ahead of print. PMID: 39449317

Name: Susan Stark
Year: 2024

Reference:

Keleman, A.A., Bollinger, R.M., Rodakowski, J., Chang, C-H., Kehrer-Dunlap A., Ances, B.M., & Stark, S.L. (in press). Exploring the Remote Administration of a Performance-Based Functional Assessment. Journal of Applied Gerontology.

Name: Zongtao Tom Lin
Year: 2024

Reference:

Mass Spectrometry Analysis of Nucleic Acid Modifications: From Beginning to Future.
Xie Y, Brás-Costa C, Lin Z, Garcia BA. Mass Spectrom Rev. 2024 Sep 22. doi: 10.1002/mas.21907. Online ahead of print. PMID: 39308031
Top-down Proteomics for the Characterization and Quantification of Calreticulin Arginylation.
Searfoss RM, Liu X, Garcia BA, Lin Z. bioRxiv [Preprint]. 2024 Aug 8:2024.08.08.607245. doi: 10.1101/2024.08.08.607245. PMID: 39149376

Name: Nicole McKay
Year: 2024

Reference:

McKay NS, Millar PR, Nicosia J, Aschenbrenner AJ, Gordon BA, Benzinger TLS, Cruchaga CC, Schindler SE, Morris JC, Hassenstab J. Pick a PACC: Comparing domain-specific and general cognitive composites in Alzheimer disease research. Neuropsychology. 2024 Jul;38(5):443-464. doi: 10.1037/neu0000949. Epub 2024 Apr 11. PubMed PMID: 38602816; PubMed Central PMCID: PMC11176005.

Name: Peter Millar
Year: 2024

Reference:

McKay, NS, Millar, PR, Aschenbrenner, AJ, Robinson, C, Pedersen, TJ, Hobbs, DA, Hassenstab, JJ, Morris, JC, Benzinger, TLS, Huff, MJ, Balota, DA, & Gordon, BA (submitted). White matter microstructure associates with global but not local task-switching costs.

Name: Millar Peter
Year: 2024

Reference:

McKay, NS, Millar, PR, Nicosia, J, Aschenbrenner, AJ, Gordon, BA, Benzinger, TLS, Cruchaga, CC, Schindler, SE, Morris, JC, & Hassenstab, JJ (2024). Pick a PACC: Comparing domain-specific and general cognitive composites in Alzheimer disease research. Neuropsychology. DOI: 10.1037/neu0000949 PMID: 38602816.

Name: Peter Millar
Year: 2024

Reference:

Name: Suzanne Schindler
Year: 2024

Reference:

Meeker KL, Luckett PH, Barthélemy NR, Hobbs DA, Chen C, Bollinger J, Ovod V, Flores S, Keefe S, Henson RL, Herries EM, McDade E, Hassenstab JJ, Xiong C, Cruchaga C, Benzinger TLS, Holtzman DM, Schindler SE, Bateman RJ, Morris JC, Gordon BA, Ances BM. Comparison of cerebrospinal fluid, plasma and neuroimaging biomarker utility in Alzheimer’s disease. Brain Commun. 2024 Mar 15;6(2):fcae081. doi: 10.1093/braincomms/fcae081. PMID: 38505230; PMCID: PMC10950051.

Name: Suzanne Schindler
Year: 2024

Reference:

Milà-Alomà M, Tosun D, Schindler SE, Hausle Z, Li Y, Petersen KK, Dage JL, Du-Cuny L, Saad ZS, Saef B, Triana-Baltzer G, Raunig DL, Coomaraswamy J, Baratta M, Meyers EA, Mordashova Y, Rubel CE, Ferber K, Kolb H, Ashton NJ, Zetterberg H, Rosenbaugh EG, Sabandal M, Shaw LM, Bannon AW, Potter WZ; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium Plasma Aβ and Phosphorylated Tau as Predictors of Amyloid and Tau Positivity in Alzheimer’s Disease Project Team. Timing of changes in Alzheimer’s disease plasma biomarkers as assessed by amyloid and tau PET clocks. medRxiv [Preprint]. 2024 Nov 14:2024.10.25.24316144. doi: 10.1101/2024.10.25.24316144. PMID: 39574864; PMCID: PMC11581066.

Name: Eva Klinman
Year: 2024

Reference:

New grant:
Longer Life foundation

Name: Suzanne Schindler
Year: 2024

Reference:

Palmqvist S, Tideman P, Mattsson-Carlgren N, Schindler SE, Smith R, Ossenkoppele R, Calling S, West T, Monane M, Verghese PB, Braunstein JB, Blennow K, Janelidze S, Stomrud E, Salvadó G, Hansson O. Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care. JAMA. 2024 Jul 28:e2413855. doi: 10.1001/jama.2024.13855. Epub ahead of print. PMID: 39068545; PMCID: PMC11284636.

Name: Suzanne Schindler
Year: 2024

Reference:

Pereira AC, Schindler SE. Cerebrospinal fluid testing in dementia diagnosis. Practical Neurology (US). 2024;23(5):23-24.

Name: Kristy Collins
Year: 2024

Reference:

Rahmani M, Dierker D, Yaeger L, Saykin A, Luckett PH, Vlassenko AG, Owens C, Jafri H, Womack K, Fripp J, Xia Y, Tosun D, Benzinger TLS, Masters CL, Lee JM, Morris JC, Goyal MS, Strain JF; ADOPIC, ADNI Investigators; Kukull W, Weiner M; Biostats, Database and Bioinformatics; Burnham S, CoxDoecke TJ, Fedyashov V, Fripp J, Shishegar R, Xiong C, Marcus D, Raniga P, Li S; Cognition; Aschenbrenner A, Hassenstab J, Lim YY, Maruff P, Sohrabi H, Robertson J, Markovic S; Imaging; Bourgeat P, Doré V, Mayo CJ, Mussoumzadeh P, Rowe C, Villemagne V; CSF and Blood; Bateman R, Fowler C, Li QX, Martins R, Schindler S, Shaw L; Genetics; Cruchaga C, Harari O, Laws S, Porter T, O’Brien E; Neuropathology; Perrin R; NACC; Kukull W; DIAN; Bateman R, McDade E; Cerebrovascular Disease (CVD) Risk; Jack C, Morris J, Yassi N; Hippocampal Sclerosis (HS-TDP43) Risk; Bourgeat P, Perrin R, Roberts B, Villemagne V; Artificial Intelligence and Machine Learning; Fedyashov V, Goudey B. Evolution of white matter hyperintensity segmentation methods and implementation over the past two decades; an incomplete shift towards deep learning. Brain Imaging Behav. 2024 Jul 31. doi: 10.1007/s11682-024-00902-w. Epub ahead of print. PMID: 39083144.

Name: Suzanne Schindler
Year: 2024

Reference:

Schindler SE, Galasko D, Pereira AC, Rabinovici GD, Salloway S, Suárez-Calvet M, Khachaturian AS, Mielke MM, Udeh-Momoh C, Weiss J, Batrla R, Bozeat S, Dwyer JR, Holzapfel D, Jones DR, Murray JF, Partrick KA, Scholler E, Vradenburg G, Young D, Algeciras-Schimnich A, Aubrecht J, Braunstein JB, Hendrix J, Hu YH, Mattke S, Monane M, Reilly D, Somers E, Teunissen CE, Shobin E, Vanderstichele H, Weiner MW, Wilson D, Hansson O. Acceptable performance of blood biomarker tests of amyloid pathology – recommendations from the Global CEO Initiative on Alzheimer’s Disease. Nat Rev Neurol. 2024 Jul;20(7):426-439. doi: 10.1038/s41582-024-00977-5. Epub 2024 Jun 12. PMID: 38866966.

Name: Suzanne Schindler
Year: 2024

Reference:

Schindler SE, Petersen KK, Saef B, Tosun D, Shaw LM, Zetterberg H, Dage JL, Ferber K, Triana-Baltzer G, Du-Cuny L, Li Y, Coomaraswamy J, Baratta M, Mordashova Y, Saad ZS, Raunig DL, Ashton NJ, Meyers EA, Rubel CE, Rosenbaugh EG, Bannon AW, Potter WZ; Alzheimer’s Disease Neuroimaging Initiative (ADNI) Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium Plasma Aβ and Phosphorylated Tau as Predictors of Amyloid and Tau Positivity in Alzheimer’s Disease Project Team. Head-to-head comparison of leading blood tests for Alzheimer’s disease pathology. Alzheimers Dement. 2024 Nov;20(11):8074-8096. doi: 10.1002/alz.14315. Epub 2024 Oct 12. Erratum in: Alzheimers Dement. 2024 Dec 30. doi: 10.1002/alz.14494. PMID: 39394841; PMCID: PMC11567821.

Name: Suzanne Schindler
Year: 2024

Reference:

Sexton CE, Bitan G, Bowles KR, Brys M, Buée L, Maina MB, Clelland CD, Cohen AD, Crary JF, Dage JL, Diaz K, Frost B, Gan L, Goate AM, Golbe LI, Hansson O, Karch CM, Kolb HC, La Joie R, Lee SE, Matallana D, Miller BL, Onyike CU, Quiroz YT, Rexach JE, Rohrer JD, Rommel A, Sadri-Vakili G, Schindler SE, Schneider JA, Sperling RA, Teunissen CE, Weninger SC, Worley SL, Zheng H, Carrillo MC. Novel avenues of tau research. Alzheimers Dement. 2024 Jan 3. doi: 10.1002/alz.13533. Epub ahead of print. PMID: 38170841.

Name: Suzanne Schindler
Year: 2024

Reference:

Shaw LM, Korecka M, Lee EB, Cousins KAQ, Vanderstichele H, Schindler SE, Tosun D, DeMarco ML, Brylska M, Wan Y, Burnham S, Sciulli A, Vulaj A, Tropea TF, Chen-Plotkin A, Wolk DA; Alzheimer’s Disease Neuroimaging Initiative. ADNI Biomarker Core: A review of progress since 2004 and future challenges. Alzheimers Dement. 2024 Nov 30. doi: 10.1002/alz.14264. Epub ahead of print. PMID: 39614747.

Name: Millar Peter
Year: 2024

Reference:

Stojanovic, M, Millar, PR, McKay, NS, Aschenbrenner, AJ, Balota, DA, Hassenstab, JJ, Benzinger, TLS, Morris, JC, & Ances, BM (under revision). The associations between attentional control, episodic memory, and Alzheimer disease biomarkers of tau and neurodegeneration.

Name: Peter Millar
Year: 2024

Reference:

Name: Suzanne Schindler
Year: 2024

Reference:

Therriault J, Schindler SE, Salvadó G, Pascoal TA, Benedet AL, Ashton NJ, Karikari TK, Apostolova L, Murray ME, Verberk I, Vogel JW, La Joie R, Gauthier S, Teunissen C, Rabinovici GD, Zetterberg H, Bateman RJ, Scheltens P, Blennow K, Sperling R, Hansson O, Jack CR Jr, Rosa-Neto P. Biomarker-based staging of Alzheimer disease: rationale and clinical applications. Nat Rev Neurol. 2024 Apr;20(4):232-244. doi: 10.1038/s41582-024-00942-2. Epub 2024 Mar 1. PMID: 38429551.

Name: Peter Millar
Year: 2024

Reference:

Tu, JC, Millar, PR, Strain, JF, Eck, A, Adeyemo, B, Snyder, AZ, Daniels, A, Karch, C, Huey, ED, McDade, E, Day, GS, Yakushev, I, Hassenstab, JJ, Morris, JC, Llibre-Guerra, JJ, …, Ances, BM, Eggebrecht, AT, Gordon, BA, & Wheelock, MD (2024). Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer disease. Network Neuroscience. DOI: 10.1162/netn_a_00395 PMCID: PMC10634945 PMID: 37961586.

Name: Millar Peter
Year: 2024

Reference:

Tu, JC, Millar, PR, Strain, JF, Eck, A, Adeyemo, B, Snyder, AZ, Daniels, A, Karch, C, Huey, ED, McDade, E, Day, GS, Yakushev, I, Hassenstab, JJ, Morris, JC, Llibre-Guerra, JJ, …, Ances, BM, Eggebrecht, AT, Gordon, BA, & Wheelock, MD (in press). Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer disease. Network Neuroscience. DOI: 10.1162/netn_a_00395.

Name: Peter Millar
Year: 2024

Reference:

Tu, JC, Millar, PR, Strain, JF, Eck, A, Adeyemo, B, Snyder, AZ, Daniels, A, Karch, C, Huey, ED, McDade, E, Day, GS, Yakushev, I, Hassenstab, JJ, Morris, JC, Llibre-Guerra, JJ, …, Ances, BM, Eggebrecht, AT, Gordon, BA, & Wheelock, MD (in press). Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer disease. Network Neuroscience. DOI: 10.1162/netn_a_00395.

Name: Emily Willroth
Year: 2024

Reference:

Willroth EC, Pfund GN, Rule PD, Hill PL, John A, Kyle K, Hassenstab J, James BD. A review of the literature on wellbeing and modifiable dementia risk factors. Ageing Res Rev. 2024 Aug;99:102380. doi: 10.1016/j.arr.2024.102380. Epub 2024 Jun 14. PMID: 38880341; PMCID: PMC11260526.

Name: Suzanne Schindler
Year: 2023

Reference:

Barthélemy NR, Saef B, Li Y, Gordon BA, He Y, Horie K, Stomrud E, Salvadó G, Janelidze S, Sato C, Ovod V, Henson RL, Fagan AM, Benzinger TLS, Xiong C, Morris JC, Hansson O, Bateman RJ, Schindler SE. CSF tau phosphorylation occupancies at T217 and T205 represent improved biomarkers of amyloid and tau pathology in Alzheimer’s disease. Nature Aging. 2023. 1-11.

Name: Suzanne Schindler
Year: 2023

Reference:

Bayat S, Roe CM, Schindler S, Murphy SA, Doherty JM, Johnson AM, Walker A, Ances BM, Morris JC, Babulal GM. Everyday Driving and Plasma Biomarkers in Alzheimer’s Disease: Leveraging Artificial Intelligence to Expand Our Diagnostic Toolkit. J Alzheimers Dis. 2023 Mar 13. doi: 10.3233/JAD-221268. Epub ahead of print. PMID: 36938737.

Name: Susan Stark
Year: 2023

Reference:

Bollinger RM, Gabel M, Coble DW, Chen SW, Keleman A, Doralus J, Chin E, Lingler JH, Grill JD, Stark SL, Edwards DF. Retention of study partners in longitudinal studies of Alzheimer disease. Submitted to Journal of Alzheimer’s Disease

Name: Rebecca Bollinger
Year: 2023

Reference:

Bollinger RM, Gabel M, Coble DW, et al. Retention of Study Partners in Longitudinal Studies of Alzheimer Disease. Journal of Alzheimer’s Disease 2023; 94(1):189-199. DOI: 10.3233/jad-230079. PMID: 37212114.

Name: Suzanne Schindler
Year: 2023

Reference:

Bonomi S, Gupta MR, Schindler SE. Inadequate reimbursement for lumbar puncture is a potential barrier to accessing new Alzheimer’s disease treatments. Alzheimers Dement. 2023 Sep 18. doi: 10.1002/alz.13473. Epub ahead of print. PMID: 37718645.

Name: Suzanne Schindler
Year: 2023

Reference:

Bradley J, Gorijala P, Schindler SE, Sung YJ, Ances B, Neuroimaging Initiative The Human Connectome Project TAD, Fernandez MV, Cruchaga C. Genetic architecture of plasma Alzheimer disease biomarkers. Hum Mol Genet. 2023 May 19:ddad087. doi: 10.1093/hmg/ddad087. Epub ahead of print. PMID: 37208024.

Name: Suzanne Schindler
Year: 2023

Reference:

Brand AL, Lawler PE, Bollinger JG, Li Y, Schindler SE, Li M, Lopez S, Ovod V, Nakamura A, Shaw LM, Zetterberg H, Hansson O, Bateman RJ. The performance of plasma amyloid beta measurements in identifying amyloid plaques in Alzheimer’s disease: a literature review. Alzheimers Res Ther. 2022 Dec 27;14(1):195. doi: 10.1186/s13195-022-01117-1. PMID: 36575454; PMCID: PMC9793600.

Name: David Carr
Year: 2023

Reference:

Carr DB and Babulal GM. Addressing the Complex Driving Needs of an Aging Population. JAMA. 2023;330(12):1187-1188. doi:10.1001/jama.2023.16093. MIHMSID 1935927

Name: David Carr
Year: 2023

Reference:

Carr DB and Babulal GM. JAMA insights. Addressing the Complex Driving Needs of an Aging Population. JAMA 2023 Sep 26;330(12):1187-1188. PMID: 37656444, PMCID: PMC10576251, DOI: 10.1001/jama.2023.16093

Name: David Carr
Year: 2023

Reference:

Carr DB, Beyene K, Doherty J, et al. Medication and Road Test Performance Among Cognitively Intact Older adults. JAMA Open Network. 2023 Sep 5;6(9):e2335651.doi: 10.1001/jamanetworkopen.2023.35651. PMID: 37773496, PMCID: PMC10543136

Name: Suzanne Schindler
Year: 2023

Reference:

Chen CD, Ponisio MR, Lang JA, Flores S, Schindler SE, Fagan AM, Morris JC, Benzinger TLS. Comparing Tau PET Visual Interpretation with Tau PET Quantification, Cerebrospinal Fluid Biomarkers, and Longitudinal Clinical Assessment. J Alzheimers Dis. 2023;93(2):765-777. doi: 10.3233/JAD-230032. PMID: 37092225; PMCID: PMC10200228.

Name: Suzanne Schindler
Year: 2023

Reference:

Chen G, McKay NS, Gordon BA, Liu J, Joseph-Mathurin N, Schindler SE, Hassenstab J, Aschenbrenner AJ, Wang Q, Schultz SA, Su Y, LaMontagne PJ, Keefe SJ, Massoumzadeh P, Cruchaga C, Xiong C, Morris JC, Benzinger TLS. Predicting cognitive decline: Which is more useful, baseline amyloid levels or longitudinal change? Neuroimage Clin. 2023 Dec 15;41:103551. doi: 10.1016/j.nicl.2023.103551. Epub ahead of print. PMID: 38150745.

Name: Suzanne Schindler
Year: 2023

Reference:

Cooley SA, Nelson B, Boerwinkle A, Yarasheski KE, Kirmess KM, Meyer MR, Schindler SE, Morris JC, Fagan A, Ances BM, O’Halloran J. Plasma Aβ42/Aβ40 ratios are not reduced in older people living with HIV. Clin Infect Dis. 2023 Jan 5:ciad001. doi: 10.1093/cid/ciad001. Epub ahead of print. PMID: 36610788.

Name: Suzanne Schindler
Year: 2023

Reference:

Cooley SA, Nelson B, Boerwinkle A, Yarasheski KE, Kirmess KM, Meyer MR, Schindler SE, Morris JC, Fagan A, Ances BM, O’Halloran JA. Plasma Aβ42/Aβ40 Ratios in Older People With Human Immunodeficiency Virus. Clin Infect Dis. 2023 May 24;76(10):1776-1783. doi: 10.1093/cid/ciad001. PMID: 36610788; PMCID: PMC10209437.

Name: Suzanne Schindler
Year: 2023

Reference:

Dage JL, Eloyan A, Thangarajah M, Hammers DB, Fagan AM, Gray JD, Schindler SE, Snoddy C, Nudelman KNH, Faber KM, Foroud T, Aisen P, Griffin P, Grinberg LT, Iaccarino L, Kirby K, Kramer J, Koeppe R, Kukull WA, La Joie R, Mundada NS, Murray ME, Rumbaugh M, Soleimani-Meigooni DN, Toga AW, Touroutoglou A, Vemuri P, Atri A, Beckett LA, Day GS, Graff-Radford NR, Duara R, Honig LS, Jones DT, Masdeu JC, Mendez MF, Musiek E, Onyike CU, Riddle M, Rogalski E, Salloway S, Sha SJ, Turner RS, Wingo TS, Wolk DA, Womack KB, Carrillo MC, Dickerson BC, Rabinovici GD, Apostolova LG; LEADS Consortium. Cerebrospinal fluid biomarkers in the Longitudinal Early-onset Alzheimer’s Disease Study. Alzheimers Dement. 2023 Jul 25. doi: 10.1002/alz.13399. Epub ahead of print. PMID: 37491668.

Name: David Carr
Year: 2023

Reference:

David B. Carr, MD; Kebede Beyene, PhD; Jason Doherty, PhD; Samantha A. Murphy, MA; Ann M. Johnson, HS; Hailee Domash, BA; Noah Riley, BA; Alexis Walker, BA; Ashwin Sabapathy, PhD; John C. Morris, MD; Ganesh M. Babulal, PhD, OTD Medication and Road Test Performance Among Cognitively Healthy Older Adults. JAMA Netw Open. 2023;6(9):e2335651. doi:10.1001/jamanetworkopen.2023.35651. NIHMSID 1936752

Name: Suzanne Schindler
Year: 2023

Reference:

Doherty JM, Murphy SA, Bayat S, Wisch JK, Johnson AM, Walker A, Schindler SE, Ances BM, Morris JC, Babulal GM. Adverse driving behaviors increase over time as a function of preclinical Alzheimer’s disease biomarkers. Alzheimers Dement. 2023 May;19(5):2014-2023. doi: 10.1002/alz.12852. Epub 2022 Nov 23. PMID: 36419201; PMCID: PMC10182221.

Name: Suzanne Schindler
Year: 2023

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Ferreiro AL, Choi J, Ryou J, Newcomer EP, Thompson R, Bollinger RM, Hall-Moore C, Ndao IM, Sax L, Benzinger TLS, Stark SL, Holtzman DM, Fagan AM, Schindler SE, Cruchaga C, Butt OH, Morris JC, Tarr PI, Ances BM, Dantas G. Gut microbiome composition may be an indicator of preclinical Alzheimer’s disease. Sci Transl Med. 2023 Jun 14;15(700):eabo2984. doi: 10.1126/scitranslmed.abo2984. Epub 2023 Jun 14. PMID: 37315112.

Name: Suzanne Schindler
Year: 2023

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Hampel H, Hu Y, Cummings J, Mattke S, Iwatsubo T, Nakamura A, Vellas B, O’Bryant S, Shaw LM, Cho M, Batrla R, Vergallo A, Blennow K, Dage J, Schindler SE. Blood-based biomarkers for Alzheimer’s disease: Current state and future use in a transformed global healthcare landscape. Neuron. 2023 Jun 5:S0896-6273(23)00390-2. doi: 10.1016/j.neuron.2023.05.017. Epub ahead of print. PMID: 37295421.

Name: Susan Stark
Year: 2023

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Kehrer-Dunlap A, Bollinger RM, Holden B, Ances BM, Stark S. Examining the impact of a health report card on follow through with fall risk recommendations: an observational study. BMC Geriatrics; under review.

Name: Susan Stark
Year: 2023

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Keleman A, Nicosia J, Bollinger RM, Wisch JK, Hassenstab J, Morris JC, Ances BM, Balota DA, Stark SL. Precipitating mechanisms of falls in preclinical Alzheimer’s disease. Journal of Alzheimer’s Disease Reports 2023;7(1):739-750.

Name: Susan Stark
Year: 2023

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Keleman AA, Chang CH, Bollinger RM, Lingler JH, Gabel M, Stark SL. Psychometric evaluation of the Perceived Research Burden Assessment (PeRBA) in longitudinal studies of Alzheimer disease using rasch analysis. Alzheimer Disease & Associated Disorders 2023;37(1):28-34.

Name: Susan Stark
Year: 2023

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Keleman AA, Nicosia J, Bollinger RM, Wisch, Hassesnstab J, Morris JC, Ances BM, Balota DA, Stark SL. It’s the body, not the brain: Precipitating mechanisms of falls in preclinical Alzheimer disease. Submitted to Journal of Alzheimer’s Disease Reports.

Name: Suzanne Schindler
Year: 2023

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Lawler PE, Bollinger JG, Schindler SE, Hodge CR, Iglesias NJ, Krishnan V, Coulton JB, Li Y, Holtzman DM, Bateman RJ. Apolipoprotein E O-glycosylation is associated with amyloid plaques and APOE genotype. Anal Biochem. 2023 Jul 1;672:115156. doi: 10.1016/j.ab.2023.115156. Epub 2023 Apr 16. PMID: 37072097.

Name: Suzanne Schindler
Year: 2023

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Lewis A, Gupta A, Oh I, Schindler SE, Ghoshal N, Abrams Z, Foraker R, Snider BJ, Morris JC, Balls-Berry J, Gupta M, Payne PRO, Lai AM. The Association Between Socioeconomic Factors, Race, and Usage of a Specialty Memory Clinic. Neurology. 2023 Aug 2:10.1212/WNL.0000000000207674. doi: 10.1212/WNL.0000000000207674. Epub ahead of print. PMID: 37532510.

Name: Suzanne Schindler
Year: 2023

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Li M, Li Y, Schindler SE, Yen D, Sutcliffe S, Babulal GM, Benzinger TLS, Lenze EJ, Bateman RJ. Design and feasibility of an Alzheimer’s disease blood test study in a diverse community-based population. Alzheimers Dement. 2023 May 19. doi: 10.1002/alz.13125. Epub ahead of print. PMID: 37204806.

Name: Suzanne Schindler
Year: 2023

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Llibre-Guerra JJ, Iaccarino L, Coble D, Edwards L, Li Y, McDade E, Strom A, Gordon B, Mundada N, Schindler SE, Tsoy E, Ma Y, Lu R, Fagan AM, Benzinger TLS, Soleimani-Meigooni D, Aschenbrenner AJ, Miller Z, Wang G, Kramer JH, Hassenstab J, Rosen HJ, Morris JC, Miller BL, Xiong C, Perrin RJ, Allegri R, Chrem P, Surace E, Berman SB, Chhatwal J, Masters CL, Farlow MR, Jucker M, Levin J, Fox NC, Day G, Gorno-Tempini ML, Boxer AL, La Joie R, Rabinovici GD, Bateman R. Longitudinal clinical, cognitive and biomarker profiles in dominantly inherited versus sporadic early-onset Alzheimer’s disease. Brain Commun. 2023 Oct 18;5(6):fcad280. doi: 10.1093/braincomms/fcad280. PMID: 37942088; PMCID: PMC10629466.

Name: Millar Peter
Year: 2023

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McKay, NS, Gordon, BA, Hornbeck, RC, Dincer, A, Flores, S, Keefe, SJ, Joseph-Mathurin, N, Jack, CR, Koeppe, R, Millar, PR, Ances, BM, …, Cruchaga, C, Hassenstab, J, Karch, C, McDade, E, Perrin, RJ, Xiong, C, Morris, JC, Bateman, RJ, & Benzinger, TLS, & the Dominantly Inherited Alzheimer Network (2023). Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN). Nature Neuroscience, 26, 1449–1460. DOI: 10.1038/s41593-023-01359-8 PMCID: PMC10400428 PMID: 37429916.

Name: Peter Millar
Year: 2023

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Name: Peter Millar
Year: 2023

Reference:

Millar, PR, Gordon, BA, Luckett, PH, Benzinger, TLS, Cruchaga, C Fagan, AM, Hassenstab, JJ, Perrin, RJ, Schindler, SE, …, the Dominantly Inherited Alzheimer Network, Bateman, RJ, Morris, JC, & Ances, BM (2023). Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study. eLife, 12, e81869. DOI: 10.7554/eLife.81869 PMCID: PMC9988262 PMID: 36607335.

Name: Millar Peter
Year: 2023

Reference:

Millar, PR, Gordon, BA, Wisch, JK, Schultz, SA, Benzinger, TLS, Cruchaga, C, Hassenstab, JJ, Ibanez, L, Karch, C, Llibre-Guerra, JJ, Morris, JC, Perrin, RJ, Supnet-Bell, C, Xiong, C, …, the Dominantly Inherited Alzheimer Network, Bateman, RJ, Ances, BM**, & McDade, E** (2023). Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease. Molecular Neurodegeneration, 18, 98, 1–17. DOI: 10.1186/s13024-023-00688-3 PMCID: PMC10729487 PMID: 38111006.

Name: Peter Millar
Year: 2023

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Name: Suzanne Schindler
Year: 2023

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Oh IY, Schindler SE, Ghoshal N, Lai AM, Payne PRO, Gupta A. Extraction of clinical phenotypes for Alzheimer’s disease dementia from clinical notes using natural language processing. JAMIA Open. 2023 Feb 24;6(1):ooad014. doi: 10.1093/jamiaopen/ooad014. PMID: 36844369; PMCID: PMC9952043.

Name: Suzanne Schindler
Year: 2023

Reference:

Schindler SE, Atri A. The role of cerebrospinal fluid and other biomarker modalities in the Alzheimer’s disease diagnostic revolution. Nature Aging. In press.

Name: Suzanne Schindler
Year: 2023

Reference:

Sung YJ, Yang C, Norton J, Johnson M, Fagan A, Bateman RJ, Perrin RJ, Morris JC, Farlow MR, Chhatwal JP, Schofield PR, Chui H, Wang F, Novotny B, Eteleeb A, Karch C, Schindler SE, Rhinn H, Johnson ECB, Oh HS, Rutledge JE, Dammer EB, Seyfried NT, Wyss-Coray T, Harari O, Cruchaga C. Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer’s disease. Sci Transl Med. 2023 Jul 5;15(703):eabq5923. doi: 10.1126/scitranslmed.abq5923. Epub 2023 Jul 5. PMID: 37406134.

Name: Susan Stark
Year: 2023

Reference:

Washington SE, Cler E, Lowery C, Stark SL. Down syndrome and Alzheimer’s disease: a scoping review of functional performance and fall risk. Alzheimer’s & Dementia Translational Research & Clinical Interventions 2023;9(2):e12393.

Name: Suzanne Schindler
Year: 2023

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Wisch JK, Gordon BA, Boerwinkle AH, Luckett PH, Bollinger JG, Ovod V, Li Y, Henson RL, West T, Meyer MR, Kirmess KM, Benzinger TLS, Fagan AM, Morris JC, Bateman RJ, Ances BM, Schindler SE. Predicting continuous amyloid PET values with CSF and plasma Aβ42/Aβ40. Alzheimers Dement (Amst). 2023 Mar 2;15(1):e12405. doi: 10.1002/dad2.12405. PMID: 36874595; PMCID: PMC9980305.

Name: Julie Wisch
Year: 2023

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Wisch, J. K., Kianfar, J., Carr, D. B., Dickerson, A. D., Vivoda, J., Harmon, A., … & Babulal, G. M. (2023). Differential impacts of road diets on driving behavior among older adults with and without preclinical Alzheimer’s pathology. Transportation Research Part F: Traffic Psychology and Behaviour, 98, 18-28. https://doi.org/10.1016/j.trf.2023.08.010

Name: Peter Millar
Year: 2023

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Wisch, JK, Babulal, GM, Petersen, KJ, Millar, PR, Schacham, E, Scroggins, S, Boerwinkle, AH, Flores, S, Keefe, SJ, Gordon, BA, Morris, JC, & Ances, BM (2023). A practitioner’s guide to geospatial analysis in a neuroimaging context. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 15, 1, e12413, 1–5. DOI: 10.1002/dad2.12413 PMCID: PMC10019584 PMID: 36935765.

Name: Peter Millar
Year: 2023

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Name: Suzanne Schindler
Year: 2023

Reference:

Xiong C, Schindler SE, Henson RL, Wolk DA, Shaw LM, Agboola F, Morris JC, Lu R, Luo J. Correlational analyses of biomarkers that are harmonized through a bridging study due to measurement errors. Stat Methods Med Res. 2023 Nov 22:9622802231215810. doi: 10.1177/09622802231215810. Epub ahead of print. PMID: 37994004.

Name: Andrew Aschenbrenner
Year: 2022

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Aschenbrenner AJ, Li Y, Henson RL, Volluz K, Hassenstab J, Verghese P, West T, Meyer MR, Kirmess KM, Fagan AM, Xiong C, Holtzman D, Morris JC, Bateman RJ, Schindler SE. Comparison of plasma and CSF biomarkers in predicting cognitive decline. Ann Clin Transl Neurol. 2022 Oct 2. doi: 10.1002/acn3.51670. Epub ahead of print. PMID: 36183195.
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Name: Suzanne Schindler
Year: 2022

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Name: Andrew Aschenbrenner
Year: 2022

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Aschenbrenner AJ, Murphy SA, Doherty JM, Johnson AM, Bayat S, Walker A, Peña Y, Hassenstab J, Morris JC, Babulal GM. Neuropsychological correlates of changes in driving behavior among clinically healthy older adults. J Gerontol B Psychol Sci Soc Sci. 2022 Jul 23:gbac101. doi: 10.1093/geronb/gbac101. Epub ahead of print. PMID: 35869666.
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Name: Suzanne Schindler
Year: 2022

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Name: Anne Fagan
Year: 2022

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Casaletto KB, Kornack J, Paolillo EW, Rojas JC, VandeBunte A, Staffaroni AS, Lee S, Heuer H, Forsberg L, Ramos EM, Miller BL, Kramer JH, Yaffe K, Petrucelli L, Boxer A, Boeve B, Gendron TF, Rosen H; ALLFTD Consortium. Association of Physical Activity With Neurofilament Light Chain Trajectories in Autosomal Dominant Frontotemporal Lobar Degeneration Variant Carriers. JAMA Neurol. 2022 Nov 14:e224178. doi: 10.1001/jamaneurol.2022.4178. Epub ahead of print. PMID: 36374516; PMCID: PMC9664369.

Name: Sarah Hartz
Year: 2022

Reference:

Hartz SM, Mozersky J, Schindler SE, Linnenbringer E, Wang J, Gordon BA, Raji CA, Moulder KL, West T, Benzinger TLS, Cruchaga C, Hassenstab JJ, Bierut LJ, Xiong C, Morris JC. A flexible modeling approach for biomarker-based computation of absolute risk of Alzheimer’s disease dementia. Alzheimers Dement. 2022 Sep 30. doi: 10.1002/alz.12781. Epub ahead of print. PMID: 36178120.

Name: Suzanne Schindler
Year: 2022

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Name: Anne Fagan
Year: 2022

Reference:

Joseph-Mathurin N, Llibre-Guerra JJ, Li Y, McCullough AA, Hofmann C, Wojtowicz J, Park E, Wang G, Preboske GM, Wang Q, Gordon BA, Chen CD, Flores S, Aggarwal NT, Berman SB, Bird TD, Black SE, Borowski B, Brooks WS, Chhatwal JP, Clarnette R, Cruchaga C, Fagan AM, Farlow M, Fox NC, Gauthier S, Hassenstab J, Hobbs DA, Holdridge KC, Honig LS, Hornbeck RC, Hsiung GR, Jack CR Jr, Jimenez-Velazquez IZ, Jucker M, Klein G, Levin J, Mancini M, Masellis M, McKay NS, Mummery CJ, Ringman JM, Shimada H, Snider BJ, Suzuki K, Wallon D, Xiong C, Yaari R, McDade E, Perrin RJ, Bateman RJ, Salloway SP, Benzinger TLS, Clifford DB; Dominantly Inherited Alzheimer Network Trials Unit. Amyloid-Related Imaging Abnormalities in the DIAN-TU-001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease. Ann Neurol. 2022 Nov;92(5):729-744. doi: 10.1002/ana.26511. Epub 2022 Oct 13. PMID: 36151869.

Name: Susan Stark
Year: 2022

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Kehrer-Dunlap A, Bollinger R, Chen S-W, Keleman A, Thompson R, Fagan A, Ances B. Higher amyloid correlates to greater loneliness during the COVID-19 pandemic. F1000Research; undergoing peer review.

Name: Peter Millar
Year: 2022

Reference:

Millar, PR, Luckett, PH, Gordon, BA, Benzinger, TLS, Schindler, SE, Fagan, AM, Cruchaga, C, Bateman, RJ, …, the Dominantly Inherited Alzheimer Network, Morris, JC, & Ances, BM (2022). Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer disease. NeuroImage, 256, 119228. DOI: 10.1016/j.neuroimage.2022.119228 PMID: 35452806.

Millar, PR, Gordon, BA, Luckett, PH, Benzinger, TLS, Cruchaga, C, Fagan, AM, Hassenstab, JJ, Perrin, RJ, Schindler, SE, …, the Dominantly Inherited Alzheimer Network, Bateman, RJ, Morris, JC, & Ances, BM (submitted). Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages.

Name: Anne Fagan
Year: 2022

Reference:

O’Connor A, Rice H, Barnes J, Ryan NS, Liu KY, Allegri RF, Berman S, Ringman JM, Cruchaga C, Farlow MR, Hassenstab J, Lee JH, Perrin RJ, Xiong C, Gordon B, Levey AI, Goate A, Graff-Radford N, Levin J, Jucker M, Benzinger T, McDade E, Mori H, Noble JM, Schofield PR, Martins RN, Salloway S, Chhatwal J, Morris JC, Bateman R, Howard R, Reeves S, Fox NC; Dominantly Inherited Alzheimer Network. First presentation with neuropsychiatric symptoms in autosomal dominant Alzheimer’s disease: the Dominantly Inherited Alzheimer’s Network Study. J Neurol Neurosurg Psychiatry. 2022 Dec 15:jnnp-2022-329843. doi: 10.1136/jnnp-2022-329843. Epub ahead of print. PMID: 36522155.

Name: Suzanne Schindler
Year: 2022

Reference:

Rosen AC, Arias JJ, Ashford JW, Blacker D, Chhatwal JP, Chin NA, Clark L, Denny SS, Goldman JS, Gleason CE, Grill JD, Heidebrink JL, Henderson VW, Lavacot JA, Lingler JH, Menon M, Nosheny RL, Oliveira FF, Parker MW, Rahman-Filipiak A, Revoori A, Rumbaugh MC, Sanchez DL, Schindler SE, Schwarz CG, Toy L, Tyrone J, Walter S, Wang LS, Wijsman EM, Zallen DT, Aggarwal NT. The Advisory Group on Risk Evidence Education for Dementia: Multidisciplinary and Open to All. J Alzheimers Dis. 2022 Jul 31. PMID: 35938255.

Name: Suzanne Schindler
Year: 2022

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Schindler SE, Karikari TK, Ashton NJ, Henson RL, Yarasheski KE, West T, Meyer MR, Kirmess KM, Li Y, Saef B, Moulder KL, Bradford D, Fagan AM, Gordon BA, Benzinger TLS, Balls-Berry J, Bateman RJ, Xiong C, Zetterberg H, Blennow K, Morris JC. Effect of Race on Prediction of Brain Amyloidosis by Plasma Aβ42/Aβ40, Phosphorylated Tau, and Neurofilament Light. Neurology. 2022 Apr 21. PMID: 35450967.

Name: Suzanne Schindler
Year: 2022

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Schindler SE, Karikari TK. Comorbidities confound Alzheimer’s blood tests. Nature Med. 2022 Jul 4. PMID: 35788176.

Name: Suzanne Schindler
Year: 2022

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Schindler SE, Karikari TK. “Comorbidities confound Alzheimer’s blood tests.” Nature Med. (2022). Schindler, S.E., Karikari, T.K. Comorbidities confound Alzheimer’s blood tests. Nature Med (2022). https://doi.org/10.1038/s41591-022-01875-3.

Name: Suzanne Schindler
Year: 2022

Reference:

Schindler SE, Li Y, Li M, Despotis A, Park E, Vittert L, Hamilton BH, Womack KB, Saef B, Holtzman DM, Morris JC, Bateman RJ, Gupta MR. Using Alzheimer’s disease blood tests to accelerate clinical trial enrollment. Alzheimers Dement. 2022 Aug 7. PMID: 35934777

Name: Suzanne Schindler
Year: 2022

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Schindler SE, Ney DE, Goss AL, Rabinovici G. “ANA Investigates: The Future of Biomarkers in Alzheimer Disease.” Ann Neurol. June 2022; https://doi.org/10.1002/ana.26437.

Name: Suzanne Schindler
Year: 2022

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Schindler SE. Predicting Symptom Onset in Sporadic Alzheimer’s Disease: “How Long Do I Have?” J Alzheimers Dis. 2022 Feb 21. PMID: 35213383

Name: Suzanne Schindler
Year: 2022

Reference:

Schindler SE. “Fluid biomarkers in dementia diagnosis.” CONTINUUM Lifelong Learning in Neurology. 2022 June; 28(3):822-833. DOI: 10.1212/CON.0000000000001083.

Name: Marissa Streitz
Year: 2022

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Streitz ML, Denny A, Xiong C, et al. Development of a Comprehensive Battery to Collect Social and Structural Determinants of Health (SSDOH) in Cognitively Normal or Very Mildly Impaired Persons. Alzheimer Dis Assoc Disord. 2022;36(2):97-102. doi:10.1097/WAD.0000000000000505

Name: Anne Fagan
Year: 2022

Reference:

Wang G, Li Y, Xiong C, McDade E, Clifford DB, Mills SL, Santacruz AM, Aschenbrenner AJ, Hassenstab J, Benzinger TLS, Gordon BA, Fagan AM, Coalier KA, Libre-Guerra JJ, McCullough A, Joseph-Mathurin N, Chen CD, Mummery C, Wendelberger BA, Gauthier S, Masellis M, Holdridge KC, Yaari R, Chatterjee S, Sims J, Delmar P, Kerchner GA, Bittner T, Hofmann C, Bateman RJ; DIAN‐TU Study Team. Evaluation of dose-dependent treatment effects after mid-trial dose escalation in biomarker, clinical, and cognitive outcomes for gantenerumab or solanezumab in dominantly inherited Alzheimer’s disease. Alzheimers Dement (Amst). 2022 Nov 3;14(1):e12367. doi: 10.1002/dad2.12367. PMID: 36348972; PMCID: PMC9632865.

Name: Suzanne Schindler
Year: 2022

Reference:

Zicha S, Bateman RJ, Shaw LM, Zetterberg H, Bannon AW, Horton WA, Baratta M, Kolb HC, Dobler I, Mordashova Y, Saad ZS, Raunig DL, Spanakis EM, Li Y, Schindler SE, Ferber K, Rubel CE, Martone RL, Weber CJ, Edelmayer RM, Meyers EA, Bollinger JG, Rosenbaugh EG, Potter WZ; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium Plasma Aβ as a Predictor of Amyloid Positivity in Alzheimer’s Disease Project Team. Comparative analytical performance of multiple plasma Aβ42 and Aβ40 assays and their ability to predict positron emission tomography amyloid positivity. Alzheimers Dement. 2022 Jul 12. PMID: 35820077.

Name: Cyrus Raji
Year: 2021

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Amjad Samara 1, Zhaolong Li 1 2, Jerrel Rutlin 1, Cyrus A Raji 3 4, Peng Sun 3, Sheng-Kwei Song 3, Tamara Hershey 1 3 4, Sarah A Eisenstein 1 3
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Name: Ganesh Babulal
Year: 2021

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Babulal GM. Inclusion of ethnoracial populations and diversity remains a key challenge in Alzheimer’s disease biofluid-based biomarker studies. Journal of the Neurological Sciences. 2021; 421:117269. PMID: 33357998

Name: Suzanne Schindler
Year: 2021

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Boerwinkle AH, Wisch JK, Chen CD, Gordon BA, Butt OH, Schindler SE, Sutphen C, Flores S, Dincer A, Benzinger TLS, Fagan AM, Morris JC, Ances BM. Temporal Correlation of CSF and Neuroimaging in the Amyloid-Tau-Neurodegeneration Model of Alzheimer Disease. Neurology. 2021 Apr 30. PMID: 33931538.

Name: Suzanne Schindler
Year: 2021

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Butt OH, Long JM, Henson RL, Herries E, Sutphen CL, Fagan AM, Cruchaga C, Ladenson JH, Holtzman DM, Morris JC, Ances BM, Schindler SE. Cognitively normal APOE ε4 carriers have specific elevation of CSF SNAP-25. Neurobiol Aging. 2021 Feb 11;102:64-72. PMID: 33765432.

Name: Suzanne Schindler
Year: 2021

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Li Y, Schindler SE, Bollinger JG, Ovod V, Mawuenyega KG, Weiner MW, Leslie SM, Masters CL, Fowler CJ, Trojanowski JQ, Korecka M, Martins RN, Janelidze S, Hansson O, Bateman RJ. Validation of Plasma Amyloid-β 42/40 for Detecting Alzheimer Disease Amyloid Plaques. Neurology. 2021 Dec 14:10.1212/WNL.0000000000013211
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Name: Jingqin Luo
Year: 2021

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Luo J, Gao F, Liu J, Wang G, Chen L, Fagan AM, Day GS, Vöglein, Chhatwal JP, Xiong C & the Dominantly Inherited Alzheimer Network. Statistical Estimation and Comparison of Group-Specific Bivariate Correlation Coefficients in Family-type Clustered Studies. Journal of Applied Statistics. NIHMS1687855.

Name: Cyrus Raji
Year: 2021

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Maria Ly 1, Cyrus A Raji 2 3, Gary Z Yu 1, Qing Wang 2, Yong Wang 2, Suzanne E Schindler 3, Hongyu An 2, Amjad Samara 4, Sarah A Eisenstein 2 4, Tamara Hershey 2 3 4 5, Gordon Smith 6, Samuel Klein 6, Jingxia Liu 7, Chengjie Xiong 7, Beau M Ances 3, John C Morris 3, Tammie L S Benzinger 2 Obesity and White Matter Neuroinflammation Related Edema in Alzheimer’s Disease Dementia Biomarker Negative Cognitively Normal Individuals J Alzheimers Dis
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Name: Suzanne Schindler
Year: 2021

Reference:

Meeker KL, Butt OH, Gordon BA, Fagan AM, Schindler SE, Morris JC, Benzinger TLS, Ances BM. Cerebrospinal fluid neurofilament light chain is a marker of aging and white matter damage. Neurobiol Dis. 2022 Feb 12;:105662. PMID: 35167933.

Name: Jonathan Kipnis
Year: 2021

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Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy.
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Name: Peter Millar
Year: 2021

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Millar, PR, Ances, BM, Gordon, BA, Benzinger, TLS, Morris, JC, & Balota, DA (2021). Evaluating cognitive relationships with resting-state and task-driven BOLD variability. Journal of Cognitive Neuroscience, 33 (2), 279-302. DOI: 10.1162/jocn_a_01645 PMCID: PMC7877897 PMID: 33135966.

Name: Samantha Murphy
Year: 2021

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Murphy SA, Babulal GM, Roe CM. The Importance of Advancing Research on Aging and Driving. Geriatrics. 2021; 6(1):7. https://doi.org/10.3390/geriatrics6010007

Name: Catherine Roe
Year: 2021

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Roe CM, Rosnick CB, Colletta A., Babulal GM. Reaction to a pandemic: Social distancing and driving among older adults during COVID-19. Journal of Applied Gerontology: The Official Journal of the Southern Gerontological Society 2021; 40(3):263-267. PMID: 33554720

Name: Suzanne Schindler
Year: 2021

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Schindler SE , Cruchaga C, Joseph A , McCue L, Farias FHG, Wilkins CH, Deming Y , Henson RL, Mikesell RJ, Piccio L, Llibre-Guerra JJ, Moulder KL , Fagan AM , Ances BM , Benzinger TLS , Xiong C , Holtzman DM, Morris JC . African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants. Neurology Genetics. 2021 Mar 4;7(2):e571. PMCID: PMC8054965.

Name: Anne Fagan
Year: 2021

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Name: Suzanne Schindler
Year: 2021

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Smith RX, Strain JF, Tanenbaum A, Fagan AM, Hassenstab J, McDade E, Schindler SE, Gordon BA, Xiong C, Chhatwal J, Jack C Jr, Karch C, Berman S, Brosch JR, Lah JJ, Brickman AM, Cash DM, Fox NC, Graff-Radford NR, Levin J, Noble J, Holtzman DM, Masters CL, Farlow MR, Laske C, Schofield PR, Marcus DS, Morris JC, Benzinger TLS, Bateman RJ, Ances BM. Resting-State Functional Connectivity Disruption as a Pathological Biomarker in Autosomal Dominant Alzheimer Disease. Brain Connect. 2021 Apr;11(3):239-249. PMID: 33430685.

Name: Anne Fagan
Year: 2020

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Allison SL, Rodebaugh TL, Johnston C, Fagan AM, Morris JC, Head D. Developing a Spatial Navigation Screening Tool Sensitive to the Preclinical Alzheimer Disease Continuum. Archives of Clinical Neuropsychology. 2020 Mar;16(3):491-500. PMCID: PMC6849466.

Name: Anne Fagan
Year: 2020

Reference:

BarthÃ©lemy NR, Li Y, Joseph-Mathurin N, Gordon BA, Hassenstab J, Benzinger TLS, Buckles V, Fagan AM, Perrin RJ, Goate AM, Morris JC, Karch CM, Xiong C, Allegri R, Mendez PC,
Berman SB, Ikeuchi T, Mori H, Shimada H, Shoji M, Suzuki K, Noble J Farlow M, Chhatwal J, Graff-Radford NR, Salloway S Schofield PR, Masters CL, Martins RN, O’Connor A, Fox NC, Levin J, Jucker M, Gabelle A, Lehmann S, Sato C, Bateman RJ, McDade E, Dominantly Inherited Alzheimer Network. A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease. Nature Medicine. 2020 Mar;26(3):398-407. PMCID: PMC7309367.

Name: Anne Fagan
Year: 2020

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Chatterjee P, Fagan AM, Xiong C, McKay M, Bhatnagar A, Wu Y, Singh AK, Taddei K, Martins I, Gardener SL, Molloy MP, Multhaup G , Masters CL, Schofield PR, Benzinger TLS , Morris JC, Bateman RJ, Greenberg SM, Wermer MJH, Buchem MAV, Sohrabi HR, Martins RN, Dominantly Inherited Alzheimer Network. Presymptomatic Dutch-Type Hereditary Cerebral Amyloid Angiopathy-Related Blood Metabolite Alterations. Journal of Alzheimers Disease. 2020 Dec 24. PMID: 33361604.

Name: Anne Fagan
Year: 2020

Reference:

Franzmeier N, Koutsouleris N, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, Duering M, Dichgans M, Levin J, Gordon BA, Lim YY, Masters CL, Rossor M, Fox NC, O’Connor A, Chhatwal J, Salloway S, Danek A, Hassenstab J, Schofield PR, Morris JC, Bateman RJ; Alzheimer’s disease neuroimaging initiative (ADNI); Dominantly Inherited Alzheimer Network (DIAN), Ewers M. Predicting sporadic Alzheimer’s disease progression via inherited Alzheimer’s disease-informed machine-learning. Alzheimers Dementia. 2020 Feb 11. PMCID: PMC7222030.

Name: Audrey Keleman
Year: 2020

Reference:

Keleman, A., Wisch, J. K., Bollinger, R. M., Grant, E. A., Benzinger, T. L., Morris, J. C., Ances, B.A., & Stark, S. L. Falls Associate with Neurodegenerative Changes in ATN Framework of Alzheimer’s Disease. Journal of Alzheimer’s disease 2020; 77(2): 745-752. PMID: 32741815.

Name: Cyrus Raji
Year: 2020

Reference:

Lauren N Koenig 1, Gregory S Day 2, Amber Salter 1, Sarah Keefe 1, Laura M Marple 1, Justin Long 2, Pamela LaMontagne 1, Parinaz Massoumzadeh 2, B Joy Snider 2, Manasa Kanthamneni 3, Cyrus A Raji 2, Nupur Ghoshal 2, Brian A Gordon 2, Michelle Miller-Thomas 1, John C Morris 2, Joshua S Shimony 1, Tammie L S Benzinger 4, Alzheimer’s Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer Network (DIAN)

Select Atrophied Regions in Alzheimer disease (SARA): An improved volumetric model for identifying Alzheimer disease dementia

Neuroimage Clin
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PMID: 32334404 PMCID: PMC7182765 DOI: 10.1016/j.nicl.2020.102248

Name: Anne Fagan
Year: 2020

Reference:

Luo J, Agboola F, Grant E, Masters CL, Albert MS, Johnson SC, McDade EM, Vöglein J, Fagan AM, Benzinger T, Massoumzadeh P, Hassenstab J, Bateman RJ, Morris JC, Perrin RJ, Chhatwal J, Jucker M, Ghetti B, Cruchaga C, Graff-Radford NR, Schofield PR, Mori H, Xiong C. Neurology. 2020 Sep 1. PMID: 32873693. Sequence of Alzheimer disease biomarker changes in cognitively normal adults: A cross-sectional study.

Name: Anne Fagan
Year: 2020

Reference:

Name: Anne Fagan
Year: 2020

Reference:

Marta Stojanovic, Yuxuan Jin, Fagan AM, Tammie L Benzinger, Jason Hassenstab, Carlos Cruchaga, John C Morris, Denise Head. Physical Exercise and Longitudinal Trajectories in Alzheimer Disease Biomarkers and Cognitive Functioning. Alzheimer Disease and Associated Disorders. 2020 Jun 9. PMCID: PMC7483844.

Name: Peter Millar
Year: 2020

Reference:

Millar, PR, Ances, BM, Gordon, BA, Benzinger, TLS, Fagan, AM, Morris, JC, & Balota, DA (2020). Evaluating resting-state BOLD variability in relation to biomarkers of preclinical Alzheimer disease. Neurobiology of Aging, 96, 233-45. DOI: 10.1016/j.neurobiolaging.2020.08.007 PMCID: PMC7877894 PMID: 33039901.

Name: Peter Millar
Year: 2020

Reference:

Millar, PR, Petersen, SE, Ances, BM, Gordon, BA, Benzinger, TLS, Morris, JC, & Balota, DA (2020). Evaluating the sensitivity of resting-state BOLD variability to age and cognition after controlling for motion and cardiovascular influences: A network-based approach. Cerebral Cortex, 30 (11), 5686-5701. DOI: 10.1093/cercor/bhaa138 PMCID: PMC7822708 PMID: 32515824.

Name: Anne Fagan
Year: 2020

Reference:

Rachel L. Henson, Eric Doran, Bradley T. Christian, Benjamin L. Handen, William E. Klunk, Florence Lai, Joseph H. Lee, H. Diana Rosas, Nicole Schupf,, Shahid H. Zaman, Ira T. Lott, and Fagan AM. Cerebrospinal fluid biomarkers of Alzheimer’s disease in a cohort of adults with Down syndrome.
Alzheimers Dementia (Amst). 2020; 12(1): e12057. PMCID: PMC7346867.

Name: Anne Fagan
Year: 2020

Reference:

Stephanie A Schultz , Jeremy F Strain , Adedamola Adedokun , Qing Wang , Oliver Preische , Jens Kuhle , Shaney Flores , Sarah Keefe , Aylin Dincer , Beau M Ances , Sarah B Berman , Adam M Brickman , David M Cash , Jasmeer Chhatwal , Carlos Cruchaga , Michael Ewers , Nick N Fox , Bernardino Ghetti , Alison Goate , Neill R Graff-Radford , Jason J Hassenstab , Russ Hornbeck , Clifford Jack Jr , Keith Johnson , Nelly Joseph-Mathurin , Celeste M Karch , Robert A Koeppe , Athene K W Lee , Johannes Levin , Colin Masters , Eric McDade , Richard J Perrin , Christopher C Rowe , Stephen Salloway , Andrew J Saykin , Reisa Sperling , Yi Su , Victor L Villemagne , Jonathan VÃ¶glein , Michael Weiner, Chengjie Xiong , Fagan AM , John C Morris , Randall J Bateman , Tammie L S Benzinger , Mathias Jucker , Brian A Gordon , Dominantly Inherited Alzheimer Network. Serum Neurofilament Light Chain Levels Are Associated With White Matter Integrity in Autosomal Dominant Alzheimer’s Disease. Neurobiology of Disease. 2020 Jun 6;142:104960. PMCID: PMC6367005.

Name: Anne Fagan
Year: 2019

Reference:

Franzmeier N, Ren J, Damm A, Monté-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, Düzel E, Rodríguez Gómez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, Buerger K, Levin J, Duering M, Dichgans M, Suárez-Calvet M, Haass C, Gordon BA, Lim YY, Masters CL, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Milz E, Moreno-Grau S, Teipel S, Grothe MJ, Kilimann I, Rossor M, Fox N, Laske C, Chhatwal J, Falkai P, Perneczky R, Lee JH, Spottke A, Boecker H, Brosseron F, Fliessbach K, Heneka MT, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero MÁ, Metzger C, Bittner D, Salloway S, Danek A, Hassenstab J, Yakushev I, Schofield PR, Morris JC, Bateman RJ, Ewers M The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer’s disease. Molecular Psychiatry. 2019 Mar 21. PMID: 30899092

Name: Yo-El Ju
Year: 2019

Reference:

Ju YS, Zangrilli MA, Finn MB, Fagan AM, Holtzman DM. Obstructive sleep apnea
treatment, slow wave activity, and amyloid-β. Ann Neurol. 2018 Dec 31. doi:
10.1002/ana.25408. [Epub ahead of print] PubMed PMID: 30597615.

Name: Anne Fagan
Year: 2019

Reference:

Ju YS, Zangrilli MA, Finn MB, Fagan AM, Holtzman DM. Obstructive sleep apnea treatment, slow wave activity, and amyloid-Î². Ann Neurol. 2019 Feb;85(2):291-295. PMCID: PMC6396979

Name: Anne Fagan
Year: 2019

Reference:

Llibre-Guerra JJ, Li Y, Schindler SE, Gordon BA, Fagan AM, Morris JC, Benzinger TLS, Hassenstab J, Wang G, Allegri R, Berman SB, Chhatwal J, Farlow MR, Holtzman DM, Jucker M, Levin J, Noble JM, Salloway S, Schofield P, Karch C, Fox NC, Xiong C, Bateman RJ, McDade E. Association of Longitudinal Changes in Cerebrospinal Fluid Total Tau and Phosphorylated Tau 181 and Brain Atrophy With Disease Progression in Patients With Alzheimer Disease. JAMA Netw Open. 2019 Dec 2;2(12):e1917126. PMID: 31825500

Name: Justin Long
Year: 2019

Reference:

Long JM, Holtzman DM. Alzheimer Disease: An Update on Pathobiology and Treatment Strategies. Cell. 2019 Sep 25. PMID: 31564456.

Name: Anne Fagan
Year: 2019

Reference:

Preische O, Schultz SA, Apel A, Kuhle J, Kaeser SA, Barro C, Gräber S, Kuder-Buletta E, LaFougere C, Laske C, Vöglein J, Levin J, Masters CL, Martins R, Schofield PR, Rossor MN, Graff-Radford NR, Salloway S, Ghetti B, Ringman JM, Noble JM, Chhatwal J, Goate AM, Benzinger TLS, Morris JC, Bateman RJ, Wang G, Fagan AM, McDade EM, Gordon BA, Jucker M; Dominantly Inherited Alzheimer Network. Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease. Nature Medicine. 2019 25(2):277-283 PMCID: PMC6367005

Name: Anne Fagan
Year: 2019

Reference:

Preische O, Schultz SA, Apel A, Kuhle J, Kaeser SA, Barro C, GrÃ¤ber S, Kuder-Buletta E, LaFougere C, Laske C, VÃ¶glein J, Levin J, Masters CL, Martins R, Schofield PR, Rossor MN, Graff-Radford NR, Salloway S, Ghetti B, Ringman JM, Noble JM, Chhatwal J, Goate AM, Benzinger TLS, Morris JC, Bateman RJ, Wang G, Fagan AM, McDade EM, Gordon BA, Jucker M; Dominantly Inherited Alzheimer Network. Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease. Nature Medicine. 2019 25(2):277-283 PMCID: PMC6367005

Name: Anne Fagan
Year: 2019

Reference:

Tsai RM, Miller Z, Koestler M, Rojas JC, Ljubenkov PA, Rosen HJ, Rabinovici GD, Fagan AM, Cobigo Y, Brown JA, Jung JI, Hare E, Geldmacher DS, Natelson-Love M, McKinley EC, Luong PN, Chuu EL, Powers R, Mumford P, Wolf A, Wang P, Shamloo M, Miller BL, Roberson ED, Boxer AL. Reactions to Multiple Ascending Doses of the Microtubule Stabilizer TPI-287 in Patients With Alzheimer Disease, Progressive Supranuclear Palsy, and Corticobasal Syndrome: A Randomized Clinical Trial. JAMA Neurology. 2019 Nov 11

Name: Anne Fagan
Year: 2019

Reference:

Wang G, Coble D, McDade EM, Hassenstab J, Fagan AM, Benzinger TLS, Bateman RJ, Morris JC, Xiong C; Dominantly Inherited Alzheimer Network (DIAN). Staging biomarkers in preclinical autosomal dominant Alzheimer’s disease by estimated years to symptom onset. Alzheimers Dementia. 2019 Feb 14. pii: S1552-5260(18)33625-2. PMCID: PMC6461496

Name: Anne Fagan
Year: 2018

Reference:

Araque Caballero MÁ, Suárez-Calvet M, Duering M, Franzmeier N, Benzinger T, Fagan AM, Bateman RJ, Jack CR, Levin J, Dichgans M, Jucker M, Karch C, Masters CL, Morris JC, Weiner M, Rossor M, Fox NC, Lee JH, Salloway S, Danek A, Goate A, Yakushev I, Hassenstab J, Schofield PR, Haass C, Ewers M. White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer’s disease. Brain. 2018 Oct 1;141(10):3065-3080. PMCID: PMC6158739

Name: Andrew Aschenbrenner
Year: 2018

Reference:

Aschenbrenner, A.J., Gordon, B.A., Benzinger, T.L.S, Morris, J. C., & Hassenstab, J. (in press). Influence of tau PET, amyloid PET, and hippocampal volume on cognition in Alzheimer disease. Neurology

Name: Brian Gordon
Year: 2018

Reference:

Day, GS, Gordon, BA, Perrin, RJ, Cairns, NJ, Beaumont, H, Schwetye, K, Ferguson, C, Sinha, N, Bucelli, R, Musiek, ES, Ghoshal, N, Rosana Ponisio, M, Vincent, B, Mishra, S, Jackson, K, Morris, JC, Benzinger, TLS, Ances, BM. (in press) [18F]-AV-1451 PET imaging in pathologically-confirmed sporadic Creutzfeldt-Jakob disease. Neurology.

Name: Brian Gordon
Year: 2018

Reference:

Gordon, BA, Blazey TM*, Su, Y, et al. (2018). Spatial patterns of longitudinal neuroimaging biomarker change in autosomal dominant Alzheimer disease. Lancet Neurology.17(3):241-250

Name: Brian Gordon
Year: 2018

Reference:

Gordon, BA, McCullough, A, Mishra, S, Blazey, TM, Su, Y, Christensen, J, Dincer, A, Jackson, K, Hornbeck, RC, Morris, JC, Ances, B, Benzinger, TLS (in press). Cross-sectional and longitudinal atrophy is preferentially associated with tau rather than AÎ² PET pathology. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring.

Name: Brian Gordon
Year: 2018

Reference:

Gordon, BA. 2018. Measures of metabolism provide insights into hippocampal sclerosis. Brain.

Name: Anne Fagan
Year: 2018

Reference:

Hansson O, Mikulskis A, Fagan AM, Teunissen C, Zetterberg H, Vanderstichele H, Molinuevo JL, Shaw LM, Vandijck M, Verbeek MM, Savage M, Mattsson N, Lewczuk P, Batrla R, Rutz S, Dean RA, Blennow K. The impact of preanalytical variables on measuring cerebrospinal fluid biomarkers for Alzheimer’s disease diagnosis: A review. Alzheimers Dement. 2018 Jun 22. pii: S1552-5260(18)30162-6. PMID: 29940161

Name: Brian Gordon
Year: 2018

Reference:

Lewczuk, P, Riederer p, Oâ€™Bryant, S et al. (2017) Cerebrospinal fluid and blood based biomarkers for neurodegenerative dementias: an update of the consensus of the task force on biological markers in psychiatry of the world federation of societies of biological psychiatry. World Journal of Biological Psychiatry.

Name: Anne Fagan
Year: 2018

Reference:

Lim YY, Hassenstab J, Goate A, Fagan AM, Benzinger TLS, Cruchaga C, McDade E, Chhatwal J, Levin J, Farlow MR, Graff-Radford NR, Laske C, Masters CL, Salloway S, Schofield P, Morris JC, Maruff P, Bateman RJ; Dominantly Inherited Alzheimer Network. Effect of BDNFVal66Met on disease markers in dominantly inherited AD. Annals of Neurology. 2018 Sep; 84(3):424-435. PMID: 30014553

Name: Anne Fagan
Year: 2018

Reference:

McDade E, Wang G, Gordon BA, Hassenstab J, Benzinger TLS, Buckles V, Fagan AM, Holtzman DM, Cairns NJ, Goate AM, Marcus DS, Morris JC, Paumier K, Xiong C, Allegri R, Berman SB, Klunk W, Noble J, Ringman J, Ghetti B, Farlow M, Sperling RA, Chhatwal J, Salloway S, Graff-Radford NR, Schofield PR, Masters C, Rossor MN, Fox NC, Levin J, Jucker M, Bateman RJ; Dominantly Inherited Alzheimer Network. Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease. Neurology. 2018 Sep 14. PMID: 30217935

Name: Peter Millar
Year: 2018

Reference:

Millar, PR, Balota, DA, Bishara, AJ, Jacoby, LL (2018). Multinomial estimates of memory processes reveal deficits of controlled retrieval in healthy aging and very mild dementia. Memory & Cognition, 46 (7), 1058-1075. DOI: 10.3758/s13421-018-0821-9 PMCID: PMC6212309 PMID: 29796864.

Name: Brian Gordon
Year: 2018

Reference:

Mishra, S, Blazey T, Holtzman, DM, Cruchaga, C, Su, Y, Morris JC, Benzinger TLS, Gordon, BA. (in press) Longitudinal brain imaging in preclinical Alzheimer disease: Impact of APOE Îµ4 genotype. Brain

Name: Anne Fagan
Year: 2018

Reference:

Patten RV, Fagan AM, Kaufman DAS. Differential Cued-Stroop Performance in Cognitively Asymptomatic Older Adults with Biomarker-Identified Risk for Alzheimer’s Disease: A Pilot Study. Current Alzheimer Research. 2018;15(9):820-827. PMID: 29623843

Name: Anne Fagan
Year: 2018

Reference:

Name: jeffrey zacks
Year: 2018

Reference:

Richmond, L. L., Sargent, J. Q., Flores, S., & Zacks, J. M. (in press). Age differences in spatial memory for mediated environments. Psychology & Aging. PMID: 30124308.

Name: Brian Gordon
Year: 2018

Reference:

Sato, C, Barthelemy, NR, Mawuenyega, KG, Patterson, BW, Gordon, BA, Jockel-Balsarotti, J, Sullivan, M, Crisp, MJ, Kasten, T, Kirmess, K, Kanaan, NM, Yarasheski, KE, Baker-Nigh, A, Benzinger, TLS, Miller, TM, Karch, CM, Bateman, RJ (accepted). Tau kinetics in the human central nervous system. Neuron.

Name: Suzanne Schindler
Year: 2018

Reference:

Schindler SE, Gray JD, Gordon BA, Xiong C, Batrla-Utermann R, Quan M, Wahl S, Benzinger TLS, Holtzman DM, Morris JC, Fagan AM. Cerebrospinal fluid biomarkers measured by Elecsys assays compared to amyloid imaging. Alz Dement 2018, Epub ahead of print.

Name: suzanne schindler
Year: 2018

Reference:

Schindler SE, Sutphen CL, Teunissen C, McCue LM, Morris JC, Holtzman DM, Mulder SD, Scheltens P, Xiong C, Fagan AM. Upward drift in cerebrospinal fluid amyloid β 42 assay values for more than 10 years. Alz Dement 2018 Jan;14(1):62-70.

Name: Brian Gordon
Year: 2018

Reference:

Su, Y, Flores, S, Hornbeck, RC, Speidel, B, Vlassenko, AG, Gordon, BA, Koeppe, RA, Mintun, MA, Klunk, WE, Xiong, C, Morris, JC, Benzinger, TLS. (accepted) Utilizing the Centiloid Scale in Cross-sectional and Longitudinal PiB PET Studies. NeuroImage: Clinical

Name: Anne Fagan
Year: 2018

Reference:

Sutphen CL, McCue L, Herries EM, Xiong C, Ladenson JH, Holtzman DM, Fagan AM, ADNI. Longitudinal decreases in multiple cerebrospinal fluid biomarkers of neuronal injury in symptomatic late onset Alzheimer’s disease. Alzheimers Dement. 2018 Mar 23. pii: S1552-5260(18)30031-1. PMID: 29580670

Name: Brian Gordon
Year: 2018

Reference:

Vlassenko, AG, Gordon, BA, Goyal, MS, Su, Y, Blazey, TM, Durbin, TJ, Couture, LE, Christensen, JJ, Hussain, J, Morris, JC, Raichle, ME, Benzinger, TLS (in press). Aerobic glycolysis and tau deposition in preclinical Alzheimer disease. Neurobiology of Aging.

Name: Carla Yuede
Year: 2018

Reference:

Yuede CM, Timson BF, Hettinger JC, Yuede KM, Edwards HM, Lawson JE, Zimmerman SD, Cirrito JR. Interactions between stress and physical activity on Alzheimer’s disease pathology. Neurobiology of Stress 2018; 8:158-171. PMID:29888311.

Name: Nigel Cairns
Year: 2017

Reference:

Abner EL, Kryscio RJ, Schmitt FA, Fardo DW, Moga DC, Ighodaro ET, Jicha GA, Yu
L, Dodge HH, Xiong C, Woltjer RL, Schneider JA, Cairns NJ, Bennett DA, Nelson PT.
Outcomes after diagnosis of mild cognitive impairment in a large autopsy series.
Ann Neurol. 2017 Apr;81(4):549-559. doi: 10.1002/ana.24903. Epub 2017 Mar 22.
PubMed PMID: 28224671; PubMed Central PMCID: PMC5401633.

Name: Ganesh Babulal
Year: 2017

Reference:

Babulal GM, Stout SH, Head D, Holtzman CM, Fagan AM, Morris JC, and Roe CM. Neuropsychiatric Symptoms and Alzheimer’s Disease Biomarkers Predict Driving Decline: Brief Report. Journal of Alzheimer’s Disease. In press (2017).

Name: Nigel Cairns
Year: 2017

Reference:

Brown BM, Sohrabi HR, Taddei K, Gardener SL, Rainey-Smith SR, Peiffer JJ,
Xiong C, Fagan AM, Benzinger T, Buckles V, Erickson KI, Clarnette R, Shah T,
Masters CL, Weiner M, Cairns N, Rossor M, Graff-Radford NR, Salloway S, Vöglein
J, Laske C, Noble J, Schofield PR, Bateman RJ, Morris JC, Martins RN; Dominantly
Inherited Alzheimer Network. Habitual exercise levels are associated with
cerebral amyloid load in presymptomatic autosomal dominant Alzheimer’s disease.
Alzheimers Dement. 2017 May 11. pii: S1552-5260(17)30147-4. doi:
10.1016/j.jalz.2017.03.008. [Epub ahead of print] PubMed PMID: 28501451.

Name: Anne Fagan
Year: 2017

Reference:

Brown BM, Sohrabi HR, Taddei K, Gardener SL, Rainey-Smith SR, Peiffer JJ, Xiong C, Fagan AM, Benzinger T, Buckles V, Erickson KI, Clarnette R, Shah T, Masters CL, Weiner M, Cairns N, Rossor M, Graff-Radford NR, Salloway S, Vöglein J, Laske C, Noble J, Schofield PR, Bateman RJ, Morris JC, Martins RN; Dominantly Inherited Alzheimer Network. Habitual exercise levels are associated with cerebral amyloid load in presymptomatic autosomal dominant Alzheimer’s disease. Alzheimers Dement. 2017 Nov;13(11):1197-1206. 2017 May 11. PMCID: PMC5675772

Name: Nigel Cairns
Year: 2017

Reference:

Davis SA, Gan KA, Dowell JA, Cairns NJ, Gitcho MA. TDP-43 expression
influences amyloidÎ² plaque deposition and tau aggregation. Neurobiol Dis. 2017
Jul;103:154-162. doi: 10.1016/j.nbd.2017.04.012. Epub 2017 Apr 20. PubMed PMID:
28416393.

Name: Nigel Cairns
Year: 2017

Reference:

Day GS, Lim TS, Hassenstab J, Goate AM, Grant EA, Roe CM, Cairns NJ, Morris
JC. Differentiating cognitive impairment due to corticobasal degeneration and
Alzheimer disease. Neurology. 2017 Mar 28;88(13):1273-1281. doi:
10.1212/WNL.0000000000003770. Epub 2017 Feb 24. PubMed PMID: 28235814; PubMed
Central PMCID: PMC5373780.

Name: Gregory Day
Year: 2017

Reference:

Day GS, Lim TS, Hassenstab J, Goate AM, Grant EA, Roe CM, Cairns NJ, Morris JC. Differentiating cognitive impairment due to corticobasal degeneration and Alzheimer disease. Neurology. In press.

Name: Anne Fagan
Year: 2017

Reference:

Deming Y, Li Z, Kapoor M, Harari O, Del-Aguila JL, Black K, Carrell D, Cai Y, Fernandez MV, Budde J, Ma S, Saef B, Howells B, Huang KL, Bertelsen S, Fagan AM, Holtzman DM,
Morris JC, Kim S, Saykin AJ, De Jager PL, Albert M, Moghekar A, O’Brien R, Riemenschneider M, Petersen RC, Blennow K, Zetterberg H, Minthon L, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Schellenberg G, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Peskind ER, Li G, Di Narzo AF. Alzheimerâ€™s Disease Neuroimaging Initiative (ADNI); Alzheimer Disease Genetic Consortium (ADGC), Kauwe JS, Goate AM, Cruchaga C Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers. Acta Neuropathol. 2017 Feb 28. PMID: 28247064

Name: Nigel Cairns
Year: 2017

Reference:

Dodge HH, Zhu J, Woltjer R, Nelson PT, Bennett DA, Cairns NJ, Fardo DW, Kaye
JA, Lyons DE, Mattek N, Schneider JA, Silbert LC, Xiong C, Yu L, Schmitt FA,
Kryscio RJ, Abner EL; SMART data consortium. Risk of incident clinical diagnosis
of Alzheimer’s disease-type dementiaÂ attributable to pathology-confirmed vascular
disease. Alzheimers Dement. 2017 Jun;13(6):613-623. doi:
10.1016/j.jalz.2016.11.003. Epub 2016 Dec 23. PubMed PMID: 28017827; PubMed
Central PMCID: PMC5466467.

Name: Brian Gordon
Year: 2017

Reference:

Husa, RA, Gordon, BA, Cochran, MM, Bertolin, M, Lordo, DN, Kirchhoff, BA (2017). Left middle caudal frontal gray matter volume mediates age effects on self-initiated elaborative encoding strategies. Neuropsychologia. 106:341-349

Name: Anne Fagan
Year: 2017

Reference:

Millar PR, Balota DA, Maddox GB, Duchek JM, Aschenbrenner AJ, Fagan AM, Benzinger TL, Morris JC. Process Dissociation Analyses of Memory Changes in Healthy Aging, Preclinical, and Very Mild Alzheimer Disease: Evidence for Isolated Recollection Deficits. Neuropsychology. 2017 Feb 16. NIHMS ID: NIHMS841051

Name: Peter Millar
Year: 2017

Reference:

Millar, PR, Balota, DA, Maddox, GB, Duchek, JM, Aschenbrenner, AJ, Fagan, AM, Benzinger, TLS, & Morris, JC (2017). Process dissociation analyses of memory changes in healthy aging, preclinical, and very mild Alzheimer disease: Evidence for isolated recollection deficits. Neuropsychology, 31 (7), 708-723. DOI: 10.1037/neu0000352 PMCID: PMC5559353 PMID: 28206782.

Name: Tammie Benzinger
Year: 2017

Reference:

Mood Changes in Cognitively Normal Older Adults are Linked to Alzheimer Disease Biomarker Levels.
Babulal GM, Ghoshal N, Head D, Vernon EK, Holtzman DM, Benzinger TL, Fagan AM, Morris JC, Roe CM.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 2016; 24(11):1095-1104. NIHMSID: NIHMS779564
PubMed [journal]PMID: 27426238 PMCID: PMC5069099

Name: Jeffrey Zacks
Year: 2017

Reference:

Richmond, L. L., Gold, D. A., & Zacks, J. M. (in press). Improving event cognition: From the laboratory to the clinic. Journal of Applied Research in Memory and Cognition.

Name: Anne Fagan
Year: 2017

Reference:

Ringman JM, Casado M, Van Berlo V, Pa J, Joseph-Mathurin N, Fagan AM, Benzinger T, Bateman RJ, Morris JC. A novel PSEN1 (S230N) mutation causing early-onset Alzheimer’s Disease associated with prosopagnosia, hoarding, and Parkinsonism. Neurosci Lett. 2017 Jul 29;657:11-15. PMID: 28764909

Name: Anne Fagan
Year: 2017

Reference:

Roe CM, Babulal GM, Head DM, Stout SH, Vernon EK, Ghoshal N, Garland B, Barco PP, Williams MM, Johnson A, Fierberg R , Fague MS, Xiong C, Mormino E10, Grant EA, Holtzman DM, Benzinger TLS, Fagan AM, Ott BR, Carr DB, Morris JC. Preclinical Alzheimer’s disease and longitudinal driving decline. Alzheimers Dement (N Y). 2017 Jan, 3(1):74-82. PMCID: PMC5396459

Name: Suzanne Schindler
Year: 2017

Reference:

Schindler SE, Jasielec MS, Weng H, Hassenstab JJ, Grober E, McCue LM, Morris JC, Holtzman DM, Xiong C, Fagan AM. Neuropsychological measures that detect early impairment and decline in preclinical Alzheimer disease. Neurobiol Aging 2017; 56:25-32. PMID: 28482211.

Name: Brian Gordon
Year: 2017

Reference:

Shruti, M, Gordon BA, Su, Y, Christensen, J, Friedrichsen, K, Jackson K, Hornbeck, R, Balota DM, Cairns, N, Ances, B, Morris, JC. Benzinger TLS (2017). Tau PET imaging in preclinical Alzheimerâ€™s Disease: Classifying tau Positivity. NeuroImage. 161, 171-178

Name: Jason Ulrich
Year: 2017

Reference:

Susanne Krasemann, Charlotte Madore, Ron Cialic, Caroline Baufeld, Narghes Calcagno, Rachid El Fatimy, Lien Beckers, Elaine O’Loughlin, Yang Xu, Zain Fanek, David J. Greco, Scott T. Smith, George Tweet, Zachary Humulock, Tobias Zrzavy, Patricia Conde-Sanroman, Mar Gacias, Zhiping Weng, Hao Chen, Emily Tjon, Fargol Mazaheri, Kristin Hartmann, Asaf Madi, Jason D. Ulrich, Markus Glatzel, Anna Worthmann, Joerg Heeren, Bogdan Budnik, Cynthia Lemere, Tsuneya Ikezu, Frank L. Heppner, Vladimir Litvak, David M. Holtzman, Hans Lassmann, Howard L. Weiner, Jordi Ochando, Christian Haass, Oleg Butovsky, The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases, Immunity, Volume 47, Issue 3, 19 September 2017, Pages 566-581.e9, ISSN 1074-7613, https://doi.org/10.1016/j.immuni.2017.08.008.

Name: Nigel Cairns
Year: 2017

Reference:

Weiner MW, Veitch DP, Aisen PS, Beckett LA, Cairns NJ, Green RC, Harvey D,
Jack CR Jr, Jagust W, Morris JC, Petersen RC, Salazar J, Saykin AJ, Shaw LM, Toga
AW, Trojanowski JQ; Alzheimer’s Disease Neuroimaging Initiative. The Alzheimer’s
Disease Neuroimaging Initiative 3: Continued innovation for clinical trial
improvement. Alzheimers Dement. 2017 May;13(5):561-571. doi:
10.1016/j.jalz.2016.10.006. Epub 2016 Dec 5. Review. PubMed PMID: 27931796.

Name: Nigel Cairns
Year: 2017

Reference:

Weiner MW, Veitch DP, Aisen PS, Beckett LA, Cairns NJ, Green RC, Harvey D,
Jack CR Jr, Jagust W, Morris JC, Petersen RC, Saykin AJ, Shaw LM, Toga AW,
Trojanowski JQ; Alzheimer’s Disease Neuroimaging Initiative. Recent publications
from the Alzheimer’s Disease Neuroimaging Initiative: Reviewing progress toward
improved AD clinical trials. Alzheimers Dement. 2017 Apr;13(4):e1-e85. doi:
10.1016/j.jalz.2016.11.007. Epub 2017 Mar 22. Review. PubMed PMID: 28342697.

Name: Nigel Cairns
Year: 2017

Reference:

Yanamandra K, Patel TK, Jiang H, Schindler S, Ulrich JD, Boxer AL, Miller BL,
Kerwin DR, Gallardo G, Stewart F, Finn MB, Cairns NJ, Verghese PB, Fogelman I,
West T, Braunstein J, Robinson G, Keyser J, Roh J, Knapik SS, Hu Y, Holtzman DM.
Anti-tau antibody administration increases plasma tau in transgenic mice and
patients with tauopathy. Sci Transl Med. 2017 Apr 19;9(386). pii: eaal2029. doi:
10.1126/scitranslmed.aal2029. PubMed PMID: 28424326.

Name: Nigel Cairns
Year: 2017

Reference:

Name: Nigel Cairns
Year: 2017

Reference:

Zhao Y, Raichle ME, Wen J, Benzinger TL, Fagan AM, Hassenstab J, Vlassenko AG,
Luo J, Cairns NJ, Christensen JJ, Morris JC, Yablonskiy DA. In vivo detection of
microstructural correlates of brain pathology in preclinical and early Alzheimer
Disease with magnetic resonance imaging. Neuroimage. 2017 Mar 1;148:296-304. doi:
10.1016/j.neuroimage.2016.12.026. Epub 2016 Dec 15. PubMed PMID: 27989773; PubMed
Central PMCID: PMC5344724.

Name: Gregory Day
Year: 2016

Reference:

A Case Study in the History of Neurology.

Day GS, Tang-Wai DF, Shamy MC.

Neurohospitalist. 2016 Oct;6(4):181-184.

PMID: 27695602

Name: Anne Fagan
Year: 2016

Reference:

Allison SL, Fagan AM, Morris JC, Head D. Spatial Navigation in Preclinical Alzheimer’s Disease.J Alzheimers Dis. 2016 Feb 9. [Epub ahead of print]

Name: Tammie Benzinger
Year: 2016

Reference:

Amyloid Imaging, Cerebrospinal Fluid Biomarkers Predict Driving Performance Among Cognitively Normal Individuals.
Roe CM, Barco PP, Head DM, Ghoshal N, Selsor N, Babulal GM, Fierberg R, Vernon EK, Shulman N, Johnson A, Fague S, Xiong C, Grant EA, Campbell A, Ott BR, Holtzman DM, Benzinger TL, Fagan AM, Carr DB, Morris JC.
Alzheimer disease and associated disorders. 2016; NIHMSID: NIHMS767136
PubMed [journal]PMID: 27128959 PMCID: PMC5085874

Name: Gregory Day
Year: 2016

Reference:

Anti N-methyl-D-aspartate receptor encephalitis: a game-changer?

Fischer CE, Golas AC, Schweizer TA, Munoz DG, Ismail Z, Qian W, Tang-Wai DF, Rotstein DL, Day GS.

Expert Rev Neurother. 2016 Jul;16(7):849-59. doi: 10.1080/14737175.2016.1184088.

PMID: 27123777

Name: Gregory Day
Year: 2016

Reference:

Anti N-methyl-D-aspartate receptor encephalitis: a game-changer?

Fischer CE, Golas AC, Schweizer TA, Munoz DG, Ismail Z, Qian W, Tang-Wai DF, Rotstein DL, Day GS.

Expert Rev Neurother. 2016 Jul;16(7):849-59. doi: 10.1080/14737175.2016.1184088. Epub 2016 May 17.

PMID: 27123777

Name: Nigel Cairns
Year: 2016

Reference:

Armstrong RA, McKee AC, Stein TD, Alvarez VE, Cairns NJ.A quantitative study of tau pathology in eleven cases of chronic traumatic encephalopathy.Neuropathol Appl Neurobiol. 2016 Mar 21

Name: david balota
Year: 2016

Reference:

Aschenbrenner AJ, Balota DA, Gordon BA, Ratcliff R, Morris JC. A diffusion model analysis of episodic recognition in individuals with a family history of Alzheimer disease: The Adult Children Study. Neuropsychology 2016; 30: 225-238. PMCID: PMC4720576.

Name: Ganesh Babulal
Year: 2016

Reference:

Babulal GM, Addison A, Ghoshal N, Stout SH, Vernon EK, Sellan M, Roe CM. Development and interval testing of a naturalistic driving methodology to evaluate driving behavior in clinical research. F1000Research. 2016; 5:1716 (doi: 10.12688/f1000research.9150.2)

Name: Anne Fagan
Year: 2016

Reference:

Babulal GM, Ghoshal N, Head D, Vernon EK, Holtzman DM, Benzinger TL, Fagan AM, Morris JC, Roe CM. Mood Changes in Cognitively Normal Older Adults are Linked to Alzheimer’s Disease Biomarker Levels. The American Journal of Geriatric Psychiatry. 2016 Apr 19 (in press).

Name: Ganesh Babulal
Year: 2016

Reference:

Babulal GM, Ghoshal N, Head D, Vernon EK, Holtzman DM, Benzinger TLS, Fagan AM, Morris JC, Roe CM. Mood Changes in Cognitively Normal Older Adults are Linked to Alzheimer Disease Biomarker Levels. The American Journal of Geriatric Psychiatry.24(11):1095-104. doi: 10.1016/j.jagp.2016.04.004. PMID: 27426238

Name: Ganesh Babulal
Year: 2016

Reference:

Babulal GM, Traub CM, Webb M, Stout SH, Addison A, Carr DB, Ott BR, Morris JC, Roe CM. Creating a driving profile for older adults using GPS devices and naturalistic driving methodology. F1000Research. 2016;5.

Name: Anne Fagan
Year: 2016

Reference:

Bateman RJ, Benzinger TL, Berry S, Clifford DB, Duggan C, Fagan AM, Fanning K, Farlow MR, Hassenstab J, McDade EM, Mills S, Paumier K, Quintana M, Salloway SP, Santacruz A, Schneider LS, Wang G, Xiong C; DIAN-TU Pharma consortium for the Dominantly Inherited Alzheimer Network The DIAN-TU next generation Alzheimer’s prevention trial: Adaptive design and disease progression model. Alzheimers Dement. 2016 Aug 29. S1552-5260(16)30048-6. PMCID: PMC5218895

Name: Kevin Black
Year: 2016

Reference:

Black KJ, Black ER, Greene DJ, Schlaggar BL. Provisional Tic Disorder: What to tell parents when their child first starts ticcing. F1000Research 2016; 5:696. PMC Journal — In Process.

Name: Anne Fagan
Year: 2016

Reference:

Brier MR, Gordon B, Friedrichsen K, McCarthy J, Stern A, Christensen J, Owen C, Aldea P, Su Y, Hassenstab J, Cairns NJ, Holtzman DM, Fagan AM, Morris JC, Benzinger TL, Ances BM. Tau and AÎ² imaging, CSF measures, and cognition in Alzheimer’s disease. Sci Transl Med. 2016 May 11;8(338):338ra66. PMID: 27169802

Name: Brian Gordon
Year: 2016

Reference:

Brier, MR, Gordon, BA, Friedrichsen K, McCarthy, J, Stern, A, Christensen, J, Alea, P, Su, Y, Hassenstab, J, Cairns, N, Holtzman, D, Fagan, A, Morris JC, Ances, BM, Benzinger, TLS. (in press) Tau imaging relationships with amyloid ï¢ï€ imaging, CSF, and cognition in Alzheimerâ€™s Disease. Science Translational Medicine

Name: Catherine Roe
Year: 2016

Reference:

Carr DB, Barco PP, Babulal GM, Stout SH, Johnson AM, Xiong C, Morris JC, Roe CM. Association of functional impairments and co-morbid conditions with driving performance among cognitively normal older adults. PloS one. 2016;11(12):e0167751. PMID: 28005921. PMCID: PMC5179007.

Name: Tammie Benzinger
Year: 2016

Reference:

Cerebrospinal Fluid Biomarkers and Reserve Variables as Predictors of Future “Non-Cognitive” Outcomes of Alzheimer’s Disease.
Ingber AP, Hassenstab J, Fagan AM, Benzinger TL, Grant EA, Holtzman DM, Morris JC, Roe CM.
Journal of Alzheimer’s disease : JAD. 2016; 52(3):1055-64. NIHMSID: NIHMS814319
PubMed [journal]PMID: 27104893 PMCID: PMC5031142

Name: Tammie Benzinger
Year: 2016

Reference:

Certified normal: Alzheimer’s disease biomarkers and normative estimates of cognitive functioning.
Hassenstab J, Chasse R, Grabow P, Benzinger TL, Fagan AM, Xiong C, Jasielec M, Grant E, Morris JC.
Neurobiology of aging. 2016; 43:23-33. NIHMSID: NIHMS772335
PubMed [journal]PMID: 27255812 PMCID: PMC4893196

Name: Anne Fagan
Year: 2016

Reference:

Chatterjee P, Lim WL, Shui G, Gupta VB, James I, Fagan AM, Xiong C, Sohrabi HR, Taddei K, Brown BM, Benzinger T, Masters C, Snowden SG, Wenk MR, Bateman RJ, Morris JC, Martins RN. Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study.J Alzheimers Dis. 2016 Jan 21;50(3):887-94. doi: 10.3233/JAD-150948.

Name: Anne Fagan
Year: 2016

Reference:

Deming Y, Black K, Carrell D, Cai Y, Del-Aguila JL, Fernandez MV, Budde J, Ma S, Saef B, Howells B, Bertelsen S, Huang KL, Sutphen CL, Tarawneh R, Fagan AM, Holtzman DM, Morris JC, Goate AM, Dougherty JD, Cruchaga C. Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40. BMC Neurol. 2016 Nov 10;16(1):217. PMCID: PMC5105244

Name: Nigel Cairns
Year: 2016

Reference:

Evaluation of Tau Imaging in Staging Alzheimer Disease and Revealing Interactions Between Î²-Amyloid and Tauopathy.
Wang L, Benzinger TL, Su Y, Christensen J, Friedrichsen K, Aldea P, McConathy J, Cairns NJ, Fagan AM, Morris JC, Ances BM.
JAMA Neurol. 2016 Jul 25. doi: 10.1001/jamaneurol.2016.2078. [Epub ahead of print]
PMID:27454922 PMC in progress

Name: Tammie Benzinger
Year: 2016

Reference:

Evaluation of Tau Imaging in Staging Alzheimer Disease and Revealing Interactions Between Î²-Amyloid and Tauopathy.
Wang L, Benzinger TL, Su Y, Christensen J, Friedrichsen K, Aldea P, McConathy J, Cairns NJ, Fagan AM, Morris JC, Ances BM.
JAMA neurology. 2016; 73(9):1070-7. NIHMSID: NIHMS830807
PubMed [journal]PMID: 27454922 PMCID: PMC5237382

Name: Anne Fagan
Year: 2016

Reference:

Gordon BA, Blazey T, Su Y, Fagan AM, Holtzman DM, Morris JC, Benzinger TL. Longitudinal β-amyloid deposition and hippocampal volume in preclinical Alzheimer disease and suspected non-Alzheimer disease pathophysiology. JAMA Neurol. 2016 Aug 22. PMID: 27548756

Name: Anne Fagan
Year: 2016

Reference:

Gordon BA, Friedrichsen K, Brier M, Blazey T, Su Y, Christensen J, Aldea P, McConathy J, Holtzman DM, Cairns NJ, Morris JC, Fagan AM, Ances BM, Benzinger TL. The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging. Brain. 2016 Jun 10. PMCID:PMC4958902

Name: Brian Gordon
Year: 2016

Reference:

Gordon, BA, Friedrichsen, K, Brier, M, Blazey, T, Su, Y, Christensen, J, Aldea, P, McConathy, J, Holtzman, DM, Cairns, NJ, Morris, JC, Fagan, AM, Ances, BM, Benzinger, TLS. (in press) The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomopgraphy tau imaging. Brain

Name: Kevin Black
Year: 2016

Reference:

Greene DJ, Black KJ, Schlaggar BL. Considerations for MRI study design and implementation in pediatric and clinical populations. Developmental Cognitive Neuroscience 2016 Apr;18:101-12. doi: 10.1016/j.dcn.2015.12.005. PubMed PMID: 26754461; PubMed Central PMCID: PMC4834255.

Name: Kevin Black
Year: 2016

Reference:

Greene DJ, Church JA, Dosenbach NU, Nielsen AN, Adeyemo B, Nardos B, Petersen SE, Black KJ, Schlaggar BL. Multivariate pattern classification of pediatric Tourette syndrome using functional connectivity MRI. Developmental Science 2016 Feb 1. doi: 10.1111/desc.12407. [Epub ahead of print] PubMed PMID: 26834084.

Name: Shannon Macauley-Rambach
Year: 2016

Reference:

Harris RA, Tindale L, Lone A, Singh O, Macauley SL, Stanley M, Holtzman DM, Bartha R, Cumming RC. Aerobic Glycolysis in the Frontal Cortex Correlates with Memory Performance in Wild-Type Mice But Not the APP/PS1 Mouse Model of Cerebral Amyloidosis. J Neurosci. 2016 Feb 10;36(6):1871-8. doi:
10.1523/JNEUROSCI.3131-15.2016. PubMed PMID: 26865611; PubMed Central PMCID: PMC4748073.

Name: Anne Fagan
Year: 2016

Reference:

Hassenstab J, Chasse R, Grabow P, Benzinger TL, Fagan AM, Xiong C, Jasielec M, Grant E, Morris JC. Certified normal: Alzheimer’s disease biomarkers and normative estimates of cognitive functioning. Neurobiol Aging. 2016 Jul;43:23-33. PMCID: PMC4893196

Name: Tammie Benzinger
Year: 2016

Reference:

Imaging and cerebrospinal fluid biomarkers in early preclinical alzheimer disease.
Vlassenko AG, McCue L, Jasielec MS, Su Y, Gordon BA, Xiong C, Holtzman DM, Benzinger TL, Morris JC, Fagan AM.
Annals of neurology. 2016; 80(3):379-87. NIHMSID: NIHMS801936
PubMed [journal]PMID: 27398953 PMCID: PMC5016232

Name: Tammie Benzinger
Year: 2016

Reference:

Impact of MR-Based Attenuation Correction on Neurologic PET Studies.
Su Y, Rubin BB, McConathy J, Laforest R, Qi J, Sharma A, Priatna A, Benzinger TL.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2016; 57(6):913-7. NIHMSID: NIHMS764142
PubMed [journal]PMID: 26823562 PMCID: PMC4891225

Name: Anne Fagan
Year: 2016

Reference:

Ingber AP, Hassenstab J, Fagan AM, Benzinger TL, Grant EA, Holtzman DM, Morris JC, Roe CM. Cerebrospinal Fluid Biomarkers and Reserve Variables as Predictors of Future “Non-Cognitive” Outcomes of Alzheimer’s Disease. J Alzheimers Dis. 2016 Apr 16. [Epub ahead of print]

Name: Anne Fagan
Year: 2016

Reference:

Jack CR Jr, Knopman DS, Chetelat G, Dickson D, Fagan AM, Frisoni GB, Jagust W, Mormino EC, Petersen RC, Sperling RA, van der Flier WM, Villemagne VL, Visser PJ, Vos SJ. Suspected non-Alzheimer disease pathophysiology – concept and controversy. Nat Rev Neurol. 2016 Jan 18. PMCID: PMC4784257

Name: Anne Fagan
Year: 2016

Reference:

Ju YE, Finn MB, Sutphen CL, Herries EM, Jerome GM, Ladenson JH, Crimmins DL, Fagan AM, Holtzman DM. Obstructive sleep apnea decreases central nervous system-derived proteins in the cerebrospinal fluid. Ann Neurol, 2016 Apr 30. PMID: 27129429

Name: Kevin Black
Year: 2016

Reference:

Koller JM, Vachon MJ, Bretthorst GL, Black KJ. Rapid Quantitative Pharmacodynamic Imaging with Bayesian Estimation. Frontiers in Neuroscience 2016 Apr 8;10:144. doi: 10.3389/fnins.2016.00144. PubMed PMID: 27092045; PubMed Central PMCID: PMC4825616.

Name: Anne Fagan
Year: 2016

Reference:

Lee S, Viqar F, Zimmerman ME, Narkhede A, Tosto G, Benzinger TL, Marcus DS, Fagan AM, Goate A, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, Martins RN, Saykin AJ, Masters CL, Ringman JM, Ryan NS, FÓ§rster S, Laske C, Schofield PR, Sperling RA, Salloway S, Correia S, Jack C, Weiner M, Bateman RJ, Morris JC, Mayeux R, Brickman AM; Dominantly Inherited Alzheimer Network. White matter hyperintensities are a core feature of Alzheimer’s disease: Evidence from the Dominantly Inherited Alzheimer Network.Ann Neurol. 2016 Mar 26. doi: 10.1002/ana.24647. [Epub ahead of print]

Name: Anne Fagan
Year: 2016

Reference:

Lewczuk P, Matzen A, Blennow K, Parnetti L, Molinuevo JL, Eusebi P, Kornhuber J, Morris JC, Fagan AM. Cerebrospinal Fluid AÎ²42/40 Corresponds Better than AÎ²42 to Amyloid PET in Alzheimer’s Disease. J Alzheimers Dis. 2016 Oct 14. PMID: 27792012

Name: Tammie Benzinger
Year: 2016

Reference:

Local and distributed PiB accumulation associated with development of preclinical Alzheimer’s disease.
Brier MR, McCarthy JE, Benzinger TL, Stern A, Su Y, Friedrichsen KA, Morris JC, Ances BM, Vlassenko AG.
Neurobiology of aging. 2016; 38:104-11.
PubMed [journal]PMID: 26827648

Name: Tammie Benzinger
Year: 2016

Reference:

Longitudinal Î²-Amyloid Deposition and Hippocampal Volume in Preclinical Alzheimer Disease and Suspected Non-Alzheimer Disease Pathophysiology.
Gordon BA, Blazey T, Su Y, Fagan AM, Holtzman DM, Morris JC, Benzinger TL.
JAMA neurology. 2016; 73(10):1192-1200. NIHMSID: NIHMS830804
PubMed [journal]PMID: 27548756 PMCID: PMC5237381

Name: Tammie Benzinger
Year: 2016

Reference:

Longitudinal relationships among biomarkers for Alzheimer disease in the Adult Children Study.
Xiong C, Jasielec MS, Weng H, Fagan AM, Benzinger TL, Head D, Hassenstab J, Grant E, Sutphen CL, Buckles V, Moulder KL, Morris JC.
Neurology. 2016; 86(16):1499-506.
PubMed [journal]PMID: 27009258 PMCID: PMC4836885

Name: Jeffrey Zacks
Year: 2016

Reference:

lores, S., Bailey, H. R., Eisenberg, M. L., & Zacks, J. M. (in press). Event segmentation improves event memory up to one month later. Journal of Experimental Psychology: Learning, Memory & Cognition. NIHMSID: 842308.

Name: Anne Fagan
Year: 2016

Reference:

Muenchhoff J, Poljak A, Thalamuthu A, Gupta VB, Chatterjee P, Raftery M, Masters CL, Morris JC, Bateman RJ, Fagan AM, Martins RN, Sachdev PS. Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer’s disease. Sci Rep. 2016 Jul 6;6:29078. PMCID: PMC4933916

Name: Tammie Benzinger
Year: 2016

Reference:

Multimodality Review of Amyloid-related Diseases of the Central Nervous System.
Miller-Thomas MM, Sipe AL, Benzinger TL, McConathy J, Connolly S, Schwetye KE.
Radiographics : a review publication of the Radiological Society of North America, Inc. 2016; 36(4):1147-63.
PubMed [journal]PMID: 27399239 PMCID: PMC4976469

Name: Gregory Day
Year: 2016

Reference:

N-methyl-D-aspartate receptor encephalitis mediates loss of intrinsic activity measured by functional MRI.

Brier MR, Day GS, Snyder AZ, Tanenbaum AB, Ances BM.

J Neurol. 2016 Jun;263(6):1083-91. doi: 10.1007/s00415-016-8083-6.

PMID: 27025853

Name: Tammie Benzinger
Year: 2016

Reference:

NIA-AA staging of preclinical Alzheimer disease: discordance and concordance of CSF and imaging biomarkers.
Vos SJ, Gordon BA, Su Y, Visser PJ, Holtzman DM, Morris JC, Fagan AM, Benzinger TL.
Neurobiology of aging. 2016; 44:1-8. NIHMSID: NIHMS788115
PubMed [journal]PMID: 27318129 PMCID: PMC4913039

Name: Gregory Day
Year: 2016

Reference:

Over-Prescribed Medications, Under-Appreciated Risks: A Review of the Cognitive Effects of Anticholinergic Medications in Older Adults.

Britt DM, Day GS.

Mo Med. 2016 May-Jun;113(3):207-14.

PMID: 27443047

Name: Gregory Day
Year: 2016

Reference:

Over-Prescribed Medications, Under-Appreciated Risks: A Review of the Cognitive Effects of Anticholinergic Medications in Older Adults.

Britt DM, Day GS.

Mo Med. 2016 May-Jun;113(3):207-14. Review.

PMID: 27443047

Name: Nigel Cairns
Year: 2016

Reference:

Pathology of the Superior Colliculus in Chronic Traumatic Encephalopathy.
Armstrong RA, McKee AC, Cairns NJ.
Optom Vis Sci. 2016 Jul 6. [Epub ahead of print]
PMID:27391531 PMC in progress

Name: Gregory Day
Year: 2016

Reference:

Phenotypic Similarities Between Late-Onset Autosomal Dominant and Sporadic Alzheimer Disease: A Single-Family Case-Control Study.

Day GS, Musiek ES, Roe CM, Norton J, Goate AM, Cruchaga C, Cairns NJ, Morris JC.

JAMA Neurol. 2016 Sep 1;73(9):1125-32. doi: 10.1001/jamaneurol.2016.1236.

PMID: 27454811

Name: Nigel Cairns
Year: 2016

Reference:

Phenotypic Similarities Between Late-Onset Autosomal Dominant and Sporadic Alzheimer Disease: A Single-Family Case-Control Study.
Day GS, Musiek ES, Roe CM, Norton J, Goate AM, Cruchaga C, Cairns NJ, Morris JC.
JAMA Neurol. 2016 Jul 25. doi: 10.1001/jamaneurol.2016.1236. [Epub ahead of print]
PMID:27454811 PMC in progress

Name: Anne Fagan
Year: 2016

Reference:

Piccio L, Deming Y, Del-Ãguila JL, Ghezzi L, Holtzman DM, Fagan AM, Fenoglio C, Galimberti D, Borroni B, Cruchaga C. Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status. Acta Neuropathol. 2016 Jan 11. NIHMS751012

Name: Tammie Benzinger
Year: 2016

Reference:

Quantitative hemodynamic PET imaging using image-derived arterial input function and a PET/MR hybrid scanner.
Su Y, Vlassenko AG, Couture LE, Benzinger TL, Snyder AZ, Derdeyn CP, Raichle ME.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016;
PubMed [journal]PMID: 27401805

Name: Jeffrey Zacks
Year: 2016

Reference:

Richmond, L. L., Gold, D. A., & Zacks, J. M. (in press). Event perception: Translations and applications. Journal of Applied Research on Memory and Cognition. NIHMSID: 831480.

Name: Catherine Roe
Year: 2016

Reference:

Roe CM, Babulal GM, Head DM, Stout SH, Vernon EK, Ghoshal N, Garland B, Barco PP, Williams MM, Johnson A, Fierberg R, Fague MS, Xiong C, Mormino E, Grant EA, Holtzman DM, Benzinger TLS, Fagan AM, Ott BR, Carr DB, Morris JC. Preclinical Alzheimer disease and longitudinal driving decline. Alzheimer’s & Dementia: Translational Research & Clinical Interventions. 2016. doi: 10.1016/j.trci.2016.11.006. (in press)

Name: Anne Fagan
Year: 2016

Reference:

Roe CM, Barco PP, Head DM, Ghoshal N, Selsor N, Babulal GM, Fierberg R, Vernon EK, Shulman N, Johnson A, Fague S, Xiong C, Grant EA, Campbell A, Ott BR, Holtzman DM, Benzinger TL, Fagan AM, Carr DB, Morris JC. Amyloid Imaging, Cerebrospinal Fluid Biomarkers Predict Driving Performance Among Cognitively Normal Individuals. Alzheimer Dis Assoc Disord. 2016 Apr 28. PMID: 27128959

Name: Catherine Roe
Year: 2016

Reference:

Roe CM, Barco PP, Head DM, Ghoshal N, Selsor N, Babulal GM, Fierberg R, Vernon EK, Shulman N, Johnson A, Fague S, Xiong C, Grant EA, Campbell A, Ott BR, Holtzman DM, Benzinger TLS, Fagan AM, Carr DB, Morris JC. Amyloid Imaging, Cerebrospinal Fluid Biomarkers Predict Driving Performance Among Cognitively Normal Individuals. Alzheimer Disease and Associated Disorders. 2016. doi: 10.1097/WAD.0000000000000154. PMID: 27128959. PMCID: PMC5085874

Name: Suzanne Schindler
Year: 2016

Reference:

Schindler SE, Holtzman DM. CSF sTREM2: marking the tipping point between preclinical AD and dementia? 2016 May 2;8(5)437-8. PMID: 26976613

Name: Kevin Black
Year: 2016

Reference:

Siddiqi SH, Abraham NK, Geiger CL, Karimi M, Perlmutter JS, Black KJ. The Human Experience with Intravenous Levodopa. Frontiers in Pharmacology 2016 Jan 6;6:307. doi: 10.3389/fphar.2015.00307. PubMed PMID: 26779024; PubMed Central PMCID: PMC4701937.

Name: Anne Fagan
Year: 2016

Reference:

Tang M, Ryman DC, McDade E, Jasielec MS, Buckles VD, Cairns NJ, Fagan AM, Goate A, Marcus DS, Xiong C, Allegri RF, Chhatwal JP, Danek A, Farlow MR, Fox NC, Ghetti B, Graff-Radford NR, Laske C, Martins RN, Masters CL, Mayeux RP, Ringman JM, Rossor MN, Salloway SP, Schofield PR, Morris JC, Bateman RJ; Dominantly Inherited Alzheimer Network (DIAN)
Neurological manifestations of autosomal dominant familial Alzheimer’s disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS). Lancet Neurol. 2016 Oct 21. (16)30229-0. PMCID: PMC5116769

Name: Anne Fagan
Year: 2016

Reference:

Name: Anne Fagan
Year: 2016

Reference:

Tarawneh R, D’Angelo G, Crimmins D, Herries E, Griest T, Fagan AM, Zipfel GJ, Ladenson JH, Morris JC, Holtzman DM. Diagnostic And Prognostic Utility of The Synaptic Marker Neurogranin In Alzheimer Disease. JAMA Neurol. 2016 Mar 28. doi: 10.1001/jamaneurol.2016.0086. NIHMS774455

Name: Nigel Cairns
Year: 2016

Reference:

Tau and AÎ² imaging, CSF measures, and cognition in Alzheimer’s disease.
Brier MR, Gordon B, Friedrichsen K, McCarthy J, Stern A, Christensen J, Owen C, Aldea P, Su Y, Hassenstab J, Cairns NJ, Holtzman DM, Fagan AM, Morris JC, Benzinger TL, Ances BM.
Sci Transl Med. 2016 May 11;8(338):338ra66. doi: 10.1126/scitranslmed.aaf2362.
PMID:27169802 PMC in progress

Name: Tammie Benzinger
Year: 2016

Reference:

Tau and AÎ² imaging, CSF measures, and cognition in Alzheimer’s disease.
Brier MR, Gordon B, Friedrichsen K, McCarthy J, Stern A, Christensen J, Owen C, Aldea P, Su Y, Hassenstab J, Cairns NJ, Holtzman DM, Fagan AM, Morris JC, Benzinger TL, Ances BM.
Science translational medicine. 2016; 8(338):338ra66.
PubMed [journal]PMID: 27169802

Name: Tammie Benzinger
Year: 2016

Reference:

The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging.
Gordon BA, Friedrichsen K, Brier M, Blazey T, Su Y, Christensen J, Aldea P, McConathy J, Holtzman DM, Cairns NJ, Morris JC, Fagan AM, Ances BM, Benzinger TL.
Brain : a journal of neurology. 2016; 139(Pt 8):2249-60.
PubMed [journal]PMID: 27286736 PMCID: PMC4958902

Name: Anne Fagan
Year: 2016

Reference:

Vlassenko AG, McCue L, Jasielec MS, Su Y, Gordon BA, Xiong C, Holtzman DM, Benzinger TL, Morris JC, Fagan AM. Imaging and cerebrospinal fluid biomarkers in early preclinical Alzheimer disease. Ann Neurol. 2016 Jul 11. PMID: 27398953

Name: Anne Fagan
Year: 2016

Reference:

Vos SJ, Gordon BA, Su Y, Visser PJ, Holtzman DM, Morris JC, Fagan AM, Benzinger TL. NIA- AA staging of preclinical Alzheimer disease: discordance and concordance of CSF and imaging biomarkers. Neurobiol Aging. 2016 Aug;44:1-8. PMCID: PMC4913039

Name: Brian Gordon
Year: 2016

Reference:

Vos, SJB, Gordon, BA, Su, Yi, Visser PJ, Cairns NJ, Holtzman, DH, Morris, JC, Fagan AM, Benzinger, TLS (in press). Preclinical Alzheimer disease stating: comparisons of CSF and imaging biomarkers. Neurobiology of Aging

Name: Anne Fagan
Year: 2016

Reference:

Wang L, Benzinger TL, Su Y, Christensen J, Friedrichsen K, Aldea P, McConathy J, Cairns NJ, Fagan AM, Morris JC, Ances BM. Evaluation of Tau Imaging in Staging Alzheimer Disease and Revealing Interactions Between β-Amyloid and Tauopathy. JAMA Neurol. 2016 Jul 25. PMID: 27454922

Name: Nigel Cairns
Year: 2016

Reference:

White matter hyperintensities are a core feature of Alzheimer’s disease: Evidence from the dominantly inherited Alzheimer network.
Lee S, Viqar F, Zimmerman ME, Narkhede A, Tosto G, Benzinger TL, Marcus DS, Fagan AM, Goate A, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, Martins RN, Saykin AJ, Masters CL, Ringman JM, Ryan NS, FÃ¶rster S, Laske C, Schofield PR, Sperling RA, Salloway S, Correia S, Jack C Jr, Weiner M, Bateman RJ, Morris JC, Mayeux R, Brickman AM; Dominantly Inherited Alzheimer Network.
Ann Neurol. 2016 Jun;79(6):929-39. doi: 10.1002/ana.24647. Epub 2016 Apr 27.
NIHMS772945

Name: Anne Fagan
Year: 2016

Reference:

Xiong C, Jasielec MS, Weng H, Fagan AM, Benzinger TL, Head D, Hassenstab J, Grant E, Sutphen CL, Buckles V, Moulder KL, Morris JC. Longitudinal relationships among biomarkers for Alzheimer disease in the Adult Children Study.Neurology. 2016 Mar 23 [Epub ahead of print]

Name: Anne Fagan
Year: 2016

Reference:

Zhao Y, Raichle ME, Wen J, Benzinger TL, Fagan AM, Hassenstab J, Vlassenko AG, Luo J, Cairns NJ, Christensen JJ, Morris JC, Yablonskiy DA. In vivo Detection of Microstructural Correlates of Brain Pathology in Preclinical and Early Alzheimer Disease with Magnetic Resonance Imaging. Neuroimage. 2016 Dec 15. PMID: 27989773

Name: Nigel Cairns
Year: 2015

Reference:

2. Guerreiro R, Escott-Price V, Darwent L, Parkkinen L, Ansorge O, Hernandez DG, Nalls MA, Clark L, Honig L, Marder K, van der Flier W, Holstege H, Louwersheimer E, Lemstra A, Scheltens P, Rogaeva E, St George-Hyslop P, Londos E, Zetterberg H, Ortega-Cubero S, Pastor P, Ferman TJ, Graff-Radford NR, Ross OA, Barber I, Braae A, Brown K, Morgan K, Maetzler W, Berg D, Troakes C, Al-Sarraj S, Lashley T, Compta Y, Revesz T, Lees A, Cairns NJ, Halliday GM, Mann D, Pickering-Brown S, Powell J, Lunnon K, Lupton MK; International Parkinson’s Disease Genomics Consortium (IPDGC), Dickson D, Hardy J, Singleton A, Bras J. 1. Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson’s and Alzheimer’s diseases. Neurobiol Aging. 2015 Nov 2. PMID: 26643944. PMC IN PROCESS

Name: Anne Fagan
Year: 2015

Reference:

Aschenbrenner AJ, Balota DA, Fagan AM, Duchek JM, Benzinger TL, Morris JC. Alzheimer Disease Cerebrospinal Fluid Biomarkers Moderate Baseline Differences and Predict Longitudinal Change in Attentional Control and Episodic Memory Composites in the Adult Children Study. J Int Neuropsychol Soc. 2015 Sep;21(8):573-83. PMCID: PMC4610253

Name: david balota
Year: 2015

Reference:

Aschenbrenner AJ, Balota DA, Fagan AM, Duchek JM, Benzinger TLS, Morris JC. Alzheimer disease cerebrospinal fluid biomarkers moderate baseline differences and predict longitudinal change in attentional control and episodic memory composites in the Adult Children Study. Journal of the International Neuropsychological Society 2015; 21: 573-583. PMCID: PMC4610253.

Name: Brian Gordon
Year: 2015

Reference:

Aschenbrenner AJ, Balota DA, Gordon BA, Ratcliff R, Morris JC. (in press). A diffusion model analysis of speeded episodic recognition in individuals with a family history of Alzheimer disease: The Adult Child Study. Neuropsychology.

Name: david balota
Year: 2015

Reference:

Aschenbrenner AJ, Balota DA, Tse CS, Fagan AM, Holtzman DM, Benzinger TLS, Morris JC. Alzheimer disease biomarkers, attentional control and semantic memory retrieval: Synergistic and mediational effects of biomarkers on a sensitive cognitive measure in non-demented older adults. Neuropsychology 2015; 29: 368-381. PMCID: PMC4362851.

Name: david balota
Year: 2015

Reference:

Aschenbrenner AJ, Balota DA. Interactive effects of working memory and trial history on Stroop interference in cognitively healthy aging. Psychology and Aging 2015; 30: 1-8. PMCID: PMC4361384.

Name: Andrew Aschenbrenner
Year: 2015

Reference:

Aschenbrenner, A. J., Balota, D. A., Fagan, A. M., Duchek, J. M., Benzinger, T. L. S. & Morris, J. C. (2015). Alzheimer disease cerebrospinal fluid biomarkers moderate baseline differences and predict longitudinal change in attentional control and episodic memory composites in the Adult Children Study. Journal of the International Neuropsychological Society, 21, 573-583. doi:10.1017/S1355617715000776. PMID: PMC4610253

Name: Andrew Aschenbrenner
Year: 2015

Reference:

Aschenbrenner, A. J., Balota, D. A., Gordon, B. A., Ratcliff, R. & Morris, J. C. (in press). A diffusion model analysis of episodic recognition in individuals with a family history of Alzheimer disease: The Adult Children Study. Neuropsychology. NIHMS# 697594

Name: Jeffrey Zacks
Year: 2015

Reference:

Bailey, H. R., & Zacks, J. M. (2015). Situation model updating in young and older adults: Global versus incremental mechanisms. Psychology & Aging, 30, 232-244. PMCID: PMC4451381.

Name: Jeffrey Zacks
Year: 2015

Reference:

Bailey, H. R., Sargent, J. Q., Flores, S., Nowotny, P., Goate, A., & Zacks, J. M. (2015). APOE Îµ4 genotype predicts memory for everyday activities. Aging, Neuropsychology, and Cognition, 22, 639-666. PMCID: PMC4683428.

Name: david balota
Year: 2015

Reference:

Balota DA, Duchek JM. Attention, Variability, and Biomarkers in Alzheimerâ€™s Disease. In Remembering: Attributions, Processes, and Control in Human Memory 2015; pp 285-303. New York: Psychology Press. ISBN: 1317619226.

Name: Catherine Roe
Year: 2015

Reference:

Barco PP, Carr DB, Rutkoski K, Xiong C, Roe CM. Interrater reliability of the Record of Driving Errors (RODE). American journal of occupational therapy. 2015;69(2):6902350020p1-p6. PMID: 26122691. PMCID: PMC4406108.

Name: Gregory Day
Year: 2015

Reference:

Britt DMI, Day GS. Over-Prescribed Medications, Under-Appreciated Risks: A review of the cognitive effects of anticholinergic medications in older adults. Missouri Medicine 2015 (In Press).

Name: Nigel Cairns
Year: 2015

Reference:

Bruno A. Benitez, Nigel J. Cairns, Robert E. Schmidt, John C. Morris, Joanne B. Norton, Carlos Cruchaga, Mark S. Sands. Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss. Acta Neuropathol Commun. 2015; 3: 73. PMCID: PMC4660676

Name: Anne Fagan
Year: 2015

Reference:

Chatterjee P, Gupta VB, Fagan AM, Jasielec MS, Xiong C, Sohrabi HR, Dhaliwal S, Taddei K, Bourgeat P, Brown BM, et al. Decreased Platelet APP Isoform Ratios in Autosomal Dominant Alzheimer’s Disease: Baseline Data from a DIAN Cohort Subset.Curr Alzheimer Res. 2015;12(2):157-64. PMCID: PMC4383703

Name: Nigel Cairns
Year: 2015

Reference:

Chung EJ, Babulal GM, Monsell SE, Cairns NJ, Roe CM, Morris JC. Clinical Features of Alzheimer Disease With and Without Lewy Bodies. JAMA Neurol. 2015 July 1; 72(7): 789–796. PMCID: PMC4501861

Name: Anne Fagan
Year: 2015

Reference:

Fagan AM. What does it mean to be ‘amyloid-positive’? Brain. 2015 Mar;138(Pt 3):514-6. PMCID: PMC4408431

Name: Anne Fagan
Year: 2015

Reference:

Fleisher AS, Chen K, Quiroz YT, Jakimovich LJ, Gutierrez Gomez M, Langois CM, Langbaum JB, Roontiva A, Thiyyagura P, Lee W, Ayutyanont N,Lopez L, Moreno S, Muñoz C, Tirado V, Acosta-Baena N, Fagan AM, Giraldo M, Garcia G, Huentelman MJ, Tariot PN, Lopera F, Reiman EM. Associations Between Biomarkers and Age in the Presenilin 1 E280A Autosomal Dominant Alzheimer Disease Kindred: A Cross-sectional Study. JAMA Neurol. 2015 Mar;72(3):316-24. PMCID: PMC4355261

Name: Anne Fagan
Year: 2015

Reference:

Gordon BA, Zacks JM, Blazey T, Benzinger TL, Morris JC, Fagan AM, Holtzman DM, Balota DA. Task-evoked fMRI changes in attention networks are associated with preclinical Alzheimer’s disease biomarkers. Neurobiol Aging. 2015 May; 36(5):1771-9. PMCID: PMC4417039

Name: david balota
Year: 2015

Reference:

Gordon BA, Zacks JM, Blazey T, Benzinger TLS, Morris JC, Fagan AM, Holtzman DM, Balota DA. Task-evoked fMRI Changes in Attention Networks are Associated with Preclinical Alzheimerâ€™s Disease Biomarkers. Neurobiology of Aging 2015; 36: 1771-1779. PMCID: PMC4417039.

Name: Brian Gordon
Year: 2015

Reference:

Gordon, BA, Najmi, S, Hsu, P, Benzinger, TLS (2015) The effects of white matter hyperintensities and amyloid in Alzheimerâ€™s disease. NeuroImage Clinical. 8:246-252 doi:10.1016/j.nicl.2015.04.017

Name: Brian Gordon
Year: 2015

Reference:

Gordon, BA, Zacks, J, Blazey, T, Benzinger, TLS, Morris, JC, Fagan, AM, Holtzman, DM, Balota, DA. (2015) Task-evoked fMRI Changes in Attention Networks are Associated with Preclinical Alzheimer Disease Biomarkers. Neurobiology of Aging. 36(5): 1771-1779 PMC4417039

Name: Nigel Cairns
Year: 2015

Reference:

Hassenstab J, Monsell SE, Mock C, Roe CM, Cairns NJ, Morris JC, Kukull W. Neuropsychological Markers of Cognitive Decline in Persons With Alzheimer Disease Neuropathology.J Neuropathol Exp Neurol. 2015 Nov;74(11):1086-92. NIHMS717503

Name: Jason Hassenstab
Year: 2015

Reference:

Hassenstab J, Ruvolo D, Jasielec M, Xiong C, Grant E, Morris JC. Absence of practice effects in preclinical Alzheimer’s disease. Neuropsychology 2015 May 25. Epub ahead of print. PMID: 26011114

Name: Nigel Cairns
Year: 2015

Reference:

Hortobagyi T and Cairns NJ. Amyotrophic lateral sclerosis and frontotemporal lobar degeneration. In G. Kovacs (editor) Neuropathology of Neurodegenerative Diseases: A Practical Guide. Cambridge University Press, Cambridge, UK, 2015, pp 209-248.

Name: david balota
Year: 2015

Reference:

Huff MJ, Balota DA, Minear M, Aschenbrenner AJ, Duchek JM. Dissociative global and local task-switching costs across younger adults, middle-aged adults, older adults, and very mild Alzheimerâ€™s disease individuals. Psychology and Aging; 30: 727-739. PMCID: PMC4681312.

Name: Andrew Aschenbrenner
Year: 2015

Reference:

Huff, M. J., Balota, D. A., Minear, M., Aschenbrenner, A. J., & Duchek, J. M. (in press). Dissociative global and local task-switching costs across young adults, older adults, and very mild Alzheimer disease individuals. Psychology and Aging

Name: Anne Fagan
Year: 2015

Reference:

Jansen WJ, Ossenkoppele R, Knol DL, Tijms BM, Scheltens P, Verhey FR, Visser PJ; Amyloid Biomarker Study Group, Aalten P, Aarsland D, Alcolea D,Alexander M, Almdahl IS, Arnold SE, Baldeiras I, Barthel H, van Berckel BN, Bibeau K, Blennow K, Brooks DJ, van Buchem MA, Camus V, Cavedo E, Chen K,Chetelat G, Cohen AD, Drzezga A, Engelborghs S, Fagan AM, Fladby T, Fleisher AS, van der Flier WM, Ford L, Forster S, Fortea J, Foskett N, Frederiksen KS,Freund-Levi Y, Frisoni GB, Froelich L, Gabryelewicz T, Gill KD, Gkatzima O, Gomez-Tortosa E, Gordon MF, Grimmer T, Hampel H, Hausner L, Hellwig S,Herukka SK, Hildebrandt H, Ishihara L, Ivanoiu A, Jagust WJ, Johannsen P, Kandimalla R, Kapaki E, Klimkowicz-Mrowiec A, Klunk WE, Kohler S, Koglin N,Kornhuber J, Kramberger MG, Van Laere K, Landau SM, Lee DY, de Leon M, Lisetti V, Lleo A, Madsen K, Maier W, Marcusson J, Mattsson N, de Mendonca A,Meulenbroek O, Meyer PT, Mintun MA, Mok V, Molinuevo JL, Mollergard HM, Morris JC, Mroczko B, Van der Mussele S, Na DL, Newberg A, Nordberg A,Nordlund A, Novak GP, Paraskevas GP, Parnetti L, Perera G, Peters O, Popp J, Prabhakar S, Rabinovici GD, Ramakers IH, Rami L, Resende de Oliveira C,Rinne JO, Rodrigue KM, Rodriguez-Rodriguez E, Roe CM, Rot U, Rowe CC, Ruther E, Sabri O, Sanchez-Juan P, Santana I, Sarazin M, Schroder J, Schutte C,Seo SW, Soetewey F, Soininen H, Spiru L, Struyfs H, Teunissen CE, Tsolaki M, Vandenberghe R, Verbeek MM, Villemagne VL, Vos SJ, van Waalwijk van Doorn LJ, Waldemar G, Wallin A, Wallin AK, Wiltfang J, Wolk DA, Zboch M, Zetterberg H. Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis. JAMA. 2015 May 19;313(19):1924-38. PMCID: PMC4486209

Name: Anne Fagan
Year: 2015

Reference:

Kester MI, Teunissen CE, Crimmins DL, Herries EM, Ladenson JH, Scheltens P, van der Flier WM, Morris JC, Holtzman DM, Fagan AM.. Neurogranin as a Cerebrospinal Fluid Biomarker for Synaptic Loss in Symptomatic Alzheimer Disease. JAMA Neurol. 2015 Sep 14:1-7. PMCID:PMC4694558

Name: Anne Fagan
Year: 2015

Reference:

Kim A, Fagan AM, Goate AM, Benzinger TL, Morris JC, Head D; Alzheimerâ€™s Disease Neuroimaging Initiative. Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory. Cogn Affect Behav Neurosci. 2015 Mar 18. PMCID: PMC4529376

Name: Tammie Benzinger
Year: 2015

Reference:

Klunk WE, Koeppe RA, Price JC, Benzinger TL, Devous MD, Sr., Jagust WJ, Johnson KA, Mathis CA, Minhas D, Pontecorvo MJ, Rowe CC, Skovronsky DM, Mintun MA. The Centiloid Project: Standardizing quantitative amyloid plaque estimation by PET. Alzheimer’s & dementia : the journal of the Alzheimer’s Association. 2015;11(1):1-15.e4. Epub 2014/12/03. doi: 10.1016/j.jalz.2014.07.003. PubMed PMID: 25443857; PubMed Central PMCID: PMC4300247.

Name: david balota
Year: 2015

Reference:

Kotyuk E, Duchek JM, Head D, Szekely A, Goate AM, Balota DA. A genetic variant COMT coding dopaminergic activity predicts personality traits in healthy elderly. Personality and Individual Differences 2015; 82: 61-66. PMCID: PMC4422069.

Name: Anne Fagan
Year: 2015

Reference:

Leung YY, Toledo JB, Nefedov A, Polikar R, Raghavan N, Xie SX, Farnum M, Schultz T, Baek Y, Deerlin VV, Hu WT, Holtzman DM, Fagan AM, Perrin RJ, Grossman M, Soares HD, Kling MA, Mailman M, Arnold SE, Narayan VA, Lee VM, Shaw LM, Baker D, Wittenberg GM, Trojanowski JQ, Wang LS. Identifying amyloid pathology-related cerebrospinal fluid biomarkers for Alzheimer’s disease in a multicohort study. Alzheimers Dement (Amst). 2015 Sep 1;1(3):339-348. PMCID: PMC4672388

Name: Brendan Lucey
Year: 2015

Reference:

Lucey BP, Gonzales C, Das U, Li J, Siemers ER, Slemmon JR, Bateman RJ, Huang Y, Fox GB, Claassen JA, Slats D, Verbeek MM, Tong G, Soares H, Savage MJ, Kennedy M, Forman M, Sjögren M, Margolin R, Chen X, Farlow MR, Dean RA, Waring JF. An integrated multi-study analysis of intra-subject variability in cerebrospinal fluid amyloid-β concentrations collected by lumbar puncture and indwelling lumbar catheter. Alzheimers Res Ther. 2015 Jul 29;7(1):53. PMID: 26225140. PMCID: PMC4518529

Name: Shannon Macauley-Rambach
Year: 2015

Reference:

Macauley SL, Holtzman DM. Recent Advances from the Bench Toward the Bedside in Alzheimer’s Disease. EBioMedicine. 2015 Jan 9;2(2):94-5. doi: 10.1016/j.ebiom.2015.01.002. eCollection 2015 Feb. No abstract available. PMID: 26137544

Name: Shannon Macauley-Rambach
Year: 2015

Reference:

Macauley SL, Stanley M, Caesar EE, Yamada SA, Raichle ME, Perez R, Mahan TE, Sutphen CL, Holtzman DM. Hyperglycemia modulates extracellular amyloid-Î² concentrations and neuronal activity in vivo. J Clin Invest. 2015 Jun;125(6):2463-7. doi: 10.1172/JCI79742. Epub 2015 May 4.
PMID: 25938784

Name: david balota
Year: 2015

Reference:

Maddox GB, Balota DA. Retrieval practice and spacing effects in and young and older adults: An examination of the benefits of desirable difficulty. Memory & Cognition 2015; 45, 5: 760-774. PMCID: PMC4480221.

Name: Anne Fagan
Year: 2015

Reference:

Monserrate AE, Ryman DC, Ma S, Xiong C, Noble JM, Ringman JM, Morris JC, Danek A, Muller-Sarnowski F, Clifford DB, McDade EM, Brooks WS, Darby DG, Masters CL, Weston PS, Farlow MR, Graff-Radford NR, Salloway SP, Fagan AM, Oliver A, Bateman RJ; for the Dominantly Inherited Alzheimer Network. Factors Associated with the Onset and Persistence of Post-Lumbar Puncture Headache. JAMA Neurol. 2015 Mar;72(3):325-32. PMCID: PMC4364538

Name: Anne Fagan
Year: 2015

Reference:

Quiroz YT, Schultz AP, Chen K, Protas HD, Brickhouse M, Fleisher AS, Langbaum JB, Thiyyagura P, Fagan AM, Shah AR, Muniz M, Arboleda-Velasquez JF, Munoz C, Garcia G, Acosta-Baena N, Giraldo M, Tirado V, RamÃrez DL, Tariot PN, Dickerson BC, Sperling RA, Lopera F, Reiman EM. Brain Imaging and Blood Biomarker Abnormalities in Children with Autosomal Dominant Alzheimer Disease: A Cross-Sectional Study. JAMA Neurol. 2015 Aug;72(8):912-9. PMCID: PMC4625544

Name: Anne Fagan
Year: 2015

Reference:

Schindler SE and Fagan AM. Autosomal dominant Alzheimer disease: a unique resource to study CSF biomarker changes in preclinical AD. Frontiers in Neurology, 2015, Jun 29;6:142. doi: 10.3389/fneur.2015.00142. eCollection 2015. Review. PMCID: PMC4483518

Name: Suzanne Schindler
Year: 2015

Reference:

Schindler SE, Fagan AM. Autosomal Dominant Alzheimer Disease: A Unique Resource to Study CSF Biomarker Changes in Preclinical AD. Front Neurol 2015; 6:142. PMID: 26175713.

Name: Suzanne Schindler
Year: 2015

Reference:

Schindler SE, Fagan AM. Autosomal Dominant Alzheimer Disease: A Unique Resource to Study CSF Biomarker Changes in Preclinical AD. Front Neurol 6:142, 2015. PMID: 26175713.

Name: Suzanne Schindler
Year: 2015

Reference:

Schindler SE, McCall JG, Yan P, Hyrc KL, Li M, Tucker CL, Lee JM, Bruchas MR, Diamond MI. Photo-activatable Cre recombinase regulates gene expression in vivo. Sci Rep. 2015 Sep 9;5:13627. PMID: 26350769.

Name: Anne Fagan
Year: 2015

Reference:

Tarawneh R, Head D, Allison S, Buckles V, Fagan AM, Ladenson JH, Morris JC, Holtzman DM. Cerebrospinal Fluid Markers of Neurodegeneration and Rates of Brain Atrophy in Early Alzheimer Disease. JAMA Neurol. 2015 Apr 13. PMCID: PMC4551490

Name: Anne Fagan
Year: 2015

Reference:

Name: david balota
Year: 2015

Reference:

Tse CS, Chang JF, Fung AWT, Lam LCW, Hau KT, Leung GTY, Balota DA. The utility of a non-verbal prospective memory measure as a sensitive marker for early-stage Alzheimerâ€™s disease in Hong Kong. International Psychogerictrics 2015; 27: 231-242. PMID: 25245181.

Name: Catherine Roe
Year: 2015

Reference:

Vernon EK, Babulal GM, Head D, Carr D, Ghoshal N, Barco PP, Morris JC, Roe CM. Adults Aged 65 and Older Use Potentially Distracting Electronic Devices While Driving. Journal of the American Geriatrics Society. 2015;63(6):1251-4. PMID: 26096403. PMCID: PMC4479409.

Name: Anne Fagan
Year: 2015

Reference:

Vos SJ, Fagan AM. Alzheimer’s disease biomarker states. Lancet Neurol. 2015 Nov 17. S1474-4422. PMID: 26597326

Name: Anne Fagan
Year: 2015

Reference:

Wang F, Gordon BA, Ryman DC, Ma S, Xiong C, Hassenstab J, Goate A, Fagan AM, Cairns NJ, Marcus DS, McDade E, Ringman JM, Graff-Radford NR, Ghetti B, Farlow MR, Sperling R, Salloway S, Schofield PR, Masters CL, Martins RN, Rossor MN, Jucker M, Danek A, Forster S, Lane CA, Morris JC, Benzinger TL, Bateman RJ. Dominantly Inherited Alzheimer Network. Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease. Neurology. 2015 Aug 5 PMCID: PMC4553024

Name: Anne Fagan
Year: 2015

Reference:

Wang L, Benzinger TL, Hassenstab J, Blazey T, Owen C, Liu J, Fagan AM, Morris JC, Ances BM. Spatially distinct atrophy is linked to Î²-amyloid and tau in preclinical Alzheimer disease. Neurology. 2015 Mar 24;84(12):1254-60. PMCID:PMC4366088

Name: Brian Gordon
Year: 2015

Reference:

Wang, F, Gordon, BA, Ryman, DC, Ma, S, Xiong, C, Hassenstab, Goate, A, Fagan, A, Cairns, NJ, Marcus, DS, Marcus, DS, McDade, E, Ringman, JM, Graff-Radford, NR, Ghetti, B, Farlow, MR, Sperling, R, Salloway, S, Schofield, PR, Masters, CL, Martins, RN, Rossor, MN, Jucker, M, Danek, A, FÃ¶rster, S, Lane, CAS, Morris, JC, Benzinger, TLS, Bateman, RJ, The Dominantly Inherited Alzheimer Network. (in press) Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease. Neurology

Name: Jeffrey Zacks
Year: 2015

Reference:

[70] Bailey, H. R., Sargent, J. Q., Flores, S., Nowotny, P., Goate, A. & Zacks, J. M. (in press). APOE ε4 genotype predicts memory for everyday activities. Aging, Neuropsychology, & Cognition. NIHMSID: 670991

Name: Anne Fagan
Year: 2014

Reference:

Aschenbrenner AJ, Balota DA, Tse CS, Fagan AM, Holtzman DM, Benzinger TL, Morris JC Alzheimer Disease Biomarkers, Attentional Control, and Semantic Memory Retrieval: Synergistic and Mediational Effects of Biomarkers on a Sensitive Cognitive Measure in Non-Demented Older Adults. Neuropsychology. 2014 Sep 15. PMCID: PMC4362851

Name: Andrew Aschenbrenner
Year: 2014

Reference:

Aschenbrenner, A.J., Balota, D.A., Tse, C.S., Fagan, A.M., Holtzman, D.M., Benzinger, T.L.S, & Morris, J.C. (2015). Alzheimer disease biomarkers, attentional control and semantic memory retrieval: Synergistic and mediational effects of biomarkers on a sensitive cognitive measure in non-demented older adults. Neuropsychology, 29, 368-391 PMIC: PMC4362851

Name: Anne Fagan
Year: 2014

Reference:

Benitez BA, Jin SC, Guerreiro R, Graham R, Lord J, Harold D, Sims R, Lambert JC, Gibbs JR, Bras J, Sassi C, Harari O, Bertelsen S, Lupton MK, Powell J, Bellenguez C, Brown K, Medway C, Haddick PC, van der Brug MP, Bhangale T, Ortmann W, Behrens T, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Haines JL, Turton J, Braae A, Barber I, Fagan AM, Holtzman DM, Morris JC; 3C Study Group; EADI consortium; Alzheimer’s Disease Genetic Consortium (ADGC); Alzheimer’s Disease Neuroimaging Initiative (ADNI); GERAD Consortium, Williams J, Kauwe JS, Amouyel P, Morgan K, Singleton A, Hardy J, Goate AM, Cruchaga C. Missense variant in TREML2 protects against Alzheimer’s disease. Neurobiol Aging. 2014 Jun;35(6):1510.e19-26. PMCID: PMC3961557

Name: Anne Fagan
Year: 2014

Reference:

PMID:24439484

Name: Anne Fagan
Year: 2014

Reference:

Blennow K, Dubois B, Fagan AM, Lewczuk P, de Leon MJ, Hampel H. Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer’s disease. Alzheimers Dement. 2014 May 2. pii: S1552-5260(14)00066-1 PMID:24795085

Name: anne fagan
Year: 2014

Reference:

Brier MR, Thomas JB, Fagan AM, Hassenstab J, Holtzman DM, Benzinger TL, Morris JC, Ances BM. Functional connectivity and graph theory in preclinical Alzheimer’s disease. Neurobiol Aging. 2014 35:757-68. PMID:24216223

Name: Anne Fagan
Year: 2014

Reference:

Brier MR, Thomas JB, Snyder AZ, Wang L, Fagan AM, Benzinger T, Morris JC, Ances BM. Unrecognized preclinical Alzheimer disease confounds rs-fcMRI studies of normal aging Neurology. 2014 Oct 28;83(18):1613-9. PMCID: PMC4223085

Name: Alison Goate
Year: 2014

Reference:

Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Denning N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Schmidt H, Kunkle B, Dunstan ML, Vronskaya M; United Kingdom Brain Expression Consortium, Johnson AD, Ruiz A, Bihoreau MT, Reitz C, Pasquier F, Hollingworth P, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, HernÃ¡ndez I, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, FiÃ©vet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, George-Hyslop PS, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, BossÃ¹ P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Garcia FS, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Scarpini E, Bonuccelli U, Mancuso M, Siciliano G, Moebus S, Mecocci P, Zompo MD, Maier W, Hampel H, Pilotto A, Frank-GarcÃa A, Panza F, Solfrizzi V, Caffarra P, Nacmias B, Perry W, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O’Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Dartigues JF, Mayeux R, Tzourio C, Hofman A, NÃ¶then MM, Graff C, Psaty BM, Haines JL, Lathrop M, Pericak-Vance MA, Launer LJ, Van Broeckhoven C, Farrer LA, van Duijn CM, Ramirez A, Seshadri S, Schellenberg GD, Amouyel P, Williams J. Gene-wide analysis detects two new susceptibility genes for Alzheimer’s disease. PLoS One. 2014; 9(6):e94661. PMCID: PMC4055488.

Name: Alison Goate
Year: 2014

Reference:

Fagan AM, Xiong C, Jasielec MS, Bateman RJ, Goate AM, Benzinger TL, Chetti B, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, SallowayS, Schofield PR, Sperling RA, Marcus D, Cairns NJ, Buckles VD, Ladenson JH, Morris JC, Holtzman DM, Dominanty Inherited Alzheimer Network. Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimerâ€™s Disease. Sci Transl Med 2014: 6(226):226ra30. PMCID: PMC4038930.

Name: Anne Fagan
Year: 2014

Reference:

Fagan AM, Xiong C, Jasielec MS, Bateman RJ, Goate AM, Benzinger TL, Ghetti B, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Salloway S, Schofield PR, Sperling RA, Marcus D, Cairns NJ, Buckles VD, Ladenson JH, Morris JC, Holtzman DM; Dominantly Inherited Alzheimer Network. Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer’s disease. Sci Transl Med. 2014 Mar 5;6(226):226ra30. doi: 10.1126/scitranslmed.3007901. PMID:24598588

Name: Nigel Cairns
Year: 2014

Reference:

Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, Frosch MP, Alafuzoff I, Antonell A, Bogdanovic N, Brooks W, Cairns NJ, Cooper-Knock J, Cotman C, Cras P, Cruts M, De Deyn PP, Decarli C, Dobson-Stone C, Engelborghs S, Fox N, Galasko D, Gearing M, Gijselinck I, Grafman J, Hartikainen P, Hatanpaa KJ, Highley JR, Hodges J, Hulette C, Ince PG, Jin LW, Kirby J, Kofler J, Kril J, Kwok JB, Levey A, Lieberman A, Llado A, Martin JJ, Masliah E, McDermott CJ, McKee A, McLean C, Mead S, Miller CA, Miller J, Munoz DG, Murrell J, Paulson H, Piguet O, Rossor M, Sanchez-Valle R, Sano M, Schneider J, Silbert LC, Spina S, van der Zee J, Van Langenhove T, Warren J, Wharton SB, White Iii CL, Woltjer RL, Trojanowski JQ, Lee VM, Van Deerlin V, Chen-Plotkin AS. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathol. 2014 Jan 19. [Epub ahead of print]

Name: Nupur Ghoshal
Year: 2014

Reference:

Ghoshal N, Perry A, McKeel D, Schmidt RE, Carter D, Norton J, Zou WQ, Xiao X, Puoti G, Notari S, Gambetti P, Morris JC, Cairns NJ. Variably Protease-sensitive Prionopathy in an Apparent Cognitively Normal 93-Year-Old. Alzheimer disease and associated disorders. May 19 2014. PMID: 24845762 NIHMS587913

Name: Brian Gordon
Year: 2014

Reference:

Gordon, BA, Blazey, T, Benzinger, TLS. Regional variability in Alzheimerâ€™s disease biomarkers. Future Neurology 2014; 9(2): 131-134

Name: Alison Goate
Year: 2014

Reference:

Harari O, Cruchaga C, Kauwe JS, Ainscough BJ, Bales K, Pickering EH, Bertelsen S, Fagan AM, Holstman DM, Morris JC, Goate AM; Alzheimerâ€™s Disease Neuroimaging Initiative. Phosphorylated tau-AÃŸ42 ratio as a continuous trait for biomarker discovery for early-stage Alzheimerâ€™s Disease in multiplex immunossasay panels of cerebrospinal fluid. Biol Psychiatry 2014; 75(9):723-31. PMCID: PMC4007142

Name: Anne Fagan
Year: 2014

Reference:

Harari O, Cruchaga C, Kauwe JS, Ainscough BJ, Bales K, Pickering EH, Bertelsen S, Fagan AM, Holtzman DM, Morris JC, Goate AM; Alzheimer’s Disease Neuroimaging Initiative. Phosphorylated tau-AÃŽÂ²42 ratio as a continuous trait for biomarker discovery for early-stage Alzheimer’s disease in multiplex immunoassay panels of cerebrospinal fluid. Biol Psychiatry. 2014 May 1;75(9):723-31. doi: 10.1016/j.biopsych.2013.11.032. Epub 2014 Jan 19. PMCID: PMC4207667

Name: David Carr
Year: 2014

Reference:

Hetland AJ, Carr DB, Wallendorf MJ, Barco PP. â€˜Potentially Driver Impairingâ€™ PDI Medication Use in Medically Impaired Adults Referred for Driving Evaluation. Ann Pharmacother. 2014 Jan 28. Epub ahead of print PMID:24473491

Name: David Carr
Year: 2014

Reference:

Hetland AJ, Carr DB. Medications and Impaired Driving: A Review of the Literature. Ann Pharmacother. 2014 Jan 28. [Epub ahead of print] PMID:24473486

Name: Nigel Cairns
Year: 2014

Reference:

Holmes BB, Furman JL, Mahan TE, Yamasaki TR, Mirbaha H, Eades WC, Belaygorod L, Cairns NJ, Holtzman DM, Diamond MI.Proteopathic tau seeding predicts tauopathy in vivo.Proc Natl Acad Sci U S A.2014 Oct 14;111(41):E4376-85. doi: 10.1073/pnas.1411649111. Epub 2014 Sep 26

Name: Alison Goate
Year: 2014

Reference:

Jin SC, Benitez BA, Karch CM, Cooper B, Skorupa T, Carrell D, Norton JB, Hsu S, Harari O, CaiY, Bertelsen S, Goate AM, Cruchaga C. Coding variants in TREM2 increase risk for Alzheimer’s disease. Hum Mol Genet. 2014 Jun 4. IN PRESS

Name: Alison Goate
Year: 2014

Reference:

Karch CM, Goate AM. Biol Psychiatry. Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis. Biol Psychiatry 2014; May 17. IN PRESS

Name: Anne Fagan
Year: 2014

Reference:

Kauwe JS, Bailey MH, Ridge PG, Perry R, Wadsworth ME, Hoyt KL, Staley LA, Karch CM, Harari O, Cruchaga C, Ainscough BJ, Bales K, Pickering EH, Bertelsen S; Alzheimer’s Disease Neuroimaging Initiative, Fagan AM, Holtzman DM, Morris JC, Goate AM Genome-Wide Association Study of CSF Levels of 59 Alzheimer’s Disease Candidate Proteins: Significant Associations with Proteins Involved in Amyloid Processing and Inflammation. PLoS Genet. 2014 Oct 23;10(10):e1004758. PMCID: PMC4207667

Name: Tammie Benzinger
Year: 2014

Reference:

Kelly JE, Mar S, D’Angelo G, Zhou G, Rajderkar D, Benzinger TL. Susceptibility-weighted imaging helps to discriminate pediatric multiple sclerosis from acute disseminated encephalomyelitis. Pediatric neurology. 2015;52(1):36-41. Epub 2014/12/24. doi: 10.1016/j.pediatrneurol.2014.10.014. PubMed PMID: 25532777; PubMed Central PMCID: PMC4275621.

Name: Cairns Nigel
Year: 2014

Reference:

Monsell SE, Mock C, Hassenstab J, Roe CM, Cairns NJ, Morris JC, Kukull W.Neuropsychological changes in asymptomatic persons with Alzheimer disease neuropathology.
Neurology. 2014 Jul 29;83(5):434-40. doi: 10.1212/WNL.0000000000000650. Epub 2014 Jun 20.
PMID:24951474

Name: Anne Fagan
Year: 2014

Reference:

O’ Bryant SE, Gupta V, Henriksen K, Edwards M, Jeromin A, Lista S, Bazenet C,
Soares H, Lovestone S, Hampel H, Montine T, Blennow K, Foroud T, Carrillo M, Graff-Radford N, Laske C, Breteler M, Shaw L, Trojanowski JQ, Schupf N, Rissman RA, Fagan AM, Oberoi P, Umek R, Weiner MW, Grammas P, Posner H, Martins R, STAR-B and BBBIG working groups. Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer’s disease research. Alzheimers Dement. 2014 Sep 27. PMCID: PMC4414664

Name: Alison Goate
Year: 2014

Reference:

Ryman DC, Acosta-Baena N, Aisen PS, Bird T, Danek A, Fox NC, Goate A, Frommelt P, Ghetti B, Langbaum JB, Lopera F, Martins R, Masters CL, Mayeux RP, McDade E, Moreno S, Reiman EM, Ringman JM, Salloway S, Schofield PR, Sperling R, Tariot PN, Xiong C, Morris JC, Bateman RJ; And the Dominantly Inherited Alzheimer Network. Symptom onset in autosomal dominant Alzheimer disease: A systematic review and meta-analysis. Neurology. 2014; 83(3):253-60. PMCID: PMC4117367.

Name: Nupur Ghoshal
Year: 2014

Reference:

Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR, Bapineuzumab, Clinical Trial I. Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer’s disease. The New England journal of medicine. Jan 23 2014;370(4):322-333. PubMed PMID: 24450891
*Ghoshal, N. Listed under Bapineuzumab 301 and 302 Clinical Trial Investigators

Name: Susan Stark
Year: 2014

Reference:

Stark SL, Silianoff TJ, Kim H, Conte JW, Morris JC. Tailored Calendar Journals to Ascertain Falls Among Older Adults. OTJR : occupation, participation and health. Forthcoming; NIHMSID#642589

Name: david balota
Year: 2014

Reference:

Storandt M, Balota DA, Aschenbrenner AJ, Morris JC. Clinical and psychological characteristics of initial cohort of the Dominantly Inherited Alzheimer Network (DIAN). Neuropsychology 2014; 1: 19-29. PMCID: PMC3877741.

Name: Tammie Benzinger
Year: 2014

Reference:

Su Y, Blazey TM, Snyder AZ, Raichle ME, Marcus DS, Ances BM, Bateman RJ, Cairns NJ, Aldea P, Cash L, Christensen JJ, Friedrichsen K, Hornbeck RC, Farrar AM, Owen CJ, Mayeux R, Brickman AM, Klunk W, Price JC, Thompson PM, Ghetti B, Saykin AJ, Sperling RA, Johnson KA, Schofield PR, Buckles V, Morris JC, Benzinger TL. Partial volume correction in quantitative amyloid imaging. NeuroImage. 2015;107:55-64. Epub 2014/12/09. doi: 10.1016/j.neuroimage.2014.11.058. PubMed PMID: 25485714; PubMed Central PMCID: PMC4300252.

Name: Anne Fagan
Year: 2014

Reference:

Sutphen CL, Jasielec MS, Shah AR, Macy EM, Xiong C, Vlassenko AG, Benzinger TL, Stoops EE, Vanderstichele HM, Brix B, Darby HD, Vandijck ML, Ladenson JH, Morris JC, Holtzman DM, Fagan AM. Longitudinal Cerebrospinal Fluid Biomarker Changes in Preclinical Alzheimer Disease During Middle Age. JAMA Neurol. 2015 Jul 6. doi: 10.1001/jamaneurol.2015.1285. [Epub ahead of print] PubMed PMID: 26147946

Name: Cairns Nigel
Year: 2014

Reference:

Thomas JB, Brier MR, Bateman RJ, Snyder AZ, Benzinger TL, Xiong C, Raichle M, Holtzman DM, Sperling RA, Mayeux R, Ghetti B, Ringman JM, Salloway S, McDade E, Rossor MN, Ourselin S, Schofield PR, Masters CL, Martins RN, Weiner MW, Thompson PM, Fox NC, Koeppe RA, Jack CR Jr, Mathis CA, Oliver A, Blazey TM, Moulder K, Buckles V, Hornbeck R, Chhatwal J, Schultz AP, Goate AM, Fagan AM, Cairns NJ, Marcus DS, Morris JC, Ances BM.Functional Connectivity in Autosomal Dominant and Late-Onset Alzheimer Disease.
JAMA Neurol. 2014 Jul 28. doi: 10.1001/jamaneurol.2014.1654. [Epub ahead of print]
PMID:25069482

Name: Anne Fagan
Year: 2014

Reference:

Thomas JB, Brier MR, Bateman RJ, Snyder AZ, Benzinger TL, Xiong C, Raichle M, Holtzman DM, Sperling RA, Mayeux R, Ghetti B, Ringman JM, Salloway S, McDade E, Rossor MN, Ourselin S, Schofield PR, Masters CL, Martins RN, Weiner MW, Thompson PM, Fox NC, Koeppe RA, Jack CR Jr, Mathis CA, Oliver A, Blazey TM, Moulder K, Buckles V, Hornbeck R, Chhatwal J, Schultz AP, Goate AM, Fagan AM, Cairns NJ, Marcus DS, Morris JC, Ances BM. Functional Connectivity in Autosomal Dominant and Late-Onset Alzheimer Disease. JAMA Neurol. 2014 Jul 28. doi: 10.1001/jamaneurol.2014.1654. [Epub ahead of print] PMID:25069482

Name: Anne Fagan
Year: 2014

Reference:

Thomas JB, Brier MR, Bateman RJ, Snyder AZ, Benzinger TL, Xiong C, Raichle M, Holtzman DM, Sperling RA, Mayeux R, Ghetti B, Ringman JM,Salloway S, McDade E, Rossor MN, Ourselin S, Schofield PR, Masters CL, Martins RN, Weiner MW, Thompson PM, Fox NC, Koeppe RA, Jack CR Jr, Mathis CA, Oliver A, Blazey TM, Moulder K, Buckles V, Hornbeck R, Chhatwal J, Schultz AP, Goate AM, Fagan AM, Cairns NJ, Marcus DS, Morris JC, Ances BM Functional connectivity in autosomal dominant and late-onset Alzheimer disease JAMA Neurol. 2014 Sep:71(9):1111-22. PMCID: PMC4240274

Name: Tammie Benzinger
Year: 2014

Reference:

Thomas JB, Brier MR, Ortega M, Benzinger TL, Ances BM. Weighted brain networks in disease: centrality and entropy in human immunodeficiency virus and aging. Neurobiology of aging. 2015;36(1):401-12. Epub 2014/07/19. doi: 10.1016/j.neurobiolaging.2014.06.019. PubMed PMID: 25034343; PubMed Central PMCID: PMC4268260.

Name: Alison Goate
Year: 2014

Reference:

Ting SK, Benzinger T, Kepe V, Fagan A, Coppola G, Porter V, Hecimovic S, Chakraverty S, Alvarez-Retuerto AI, Goate A, Ringman JM. A novel PSEN1 mutation (1238M) associated with Early-Onset Alzheimerâ€™s Disease in an African-American woman. J Alzheimers Disease 2014; 40(2):271-5. PMCID: PMC397231

Name: anne fagan
Year: 2014

Reference:

Ting SK, Benzinger T, Kepe V, Fagan A, Coppola G, Porter V, Hecimovic S, Chakraverty S, Alvarez-Retuerto AI, Goate A, Ringman JM. A Novel PSEN1 Mutation (I238M) associated with Early-Onset Alzheimer’s Disease in an African-American Woman. J Alzheimers Dis. 2014 Jan 7. [Epub ahead of print] PMID:24413619

Name: Yvette Sheline
Year: 2014

Reference:

Y. I. Sheline, T. West, K. Yarasheski, M. S. Jasielec, J. C. Hettinger, D. L. Tripoli, C. Xiong, C. Frederiksen, M. V. Grzelak, R. J. Bateman, J. C. Morris, J.-M. Lee, J. R. Cirrito, Reply to comment on â€œAn antidepressant decreases CSF Ab production in healthy individuals and in transgenic AD mice.â€œ Sci. Transl. Med. 6, 268lr4 (2014).
PMID: 25540323

Name: Yvette Sheline
Year: 2014

Reference:

Y. I. Sheline, T. West, K. Yarasheski, R. Swarm, M. S. Jasielec, J. R. Fisher, W. D. Ficker, P. Yan, C. Xiong, C. Frederiksen, M. V. Grzelak, R. Chott, R. J. Bateman, J. C. Morris, M. A. Mintun, J. M. Lee, J. R. Cirrito, An antidepressant decreases CSF Ab production in healthy individuals and in transgenic AD mice. Sci. Transl. Med. 6, 236re4 (2014).
PMID: 24828079

Name: Tammie Benzinger
Year: 2014

Reference:

Zhou Y, Amundson PK, Yu F, Kessler MM, Benzinger TL, Wippold FJ. Automated classification of radiology reports to facilitate retrospective study in radiology. Journal of digital imaging. 2014;27(6):730-6. Epub 2014/05/31. doi: 10.1007/s10278-014-9708-x. PubMed PMID: 24874407. PubMed Central PMCID: In Process.

Name: Nigel Cairns
Year: 2013

Reference:

Armstrong RA, Cairns NJ.Spatial patterns of the tau pathology in progressive supranuclear palsy.Neurol Sci. 2013 Mar;34(3):337-44. doi: 10.1007/s10072-012-1006-0. Epub 2012 Mar 13.
PMID:22411688

Name: Nigel Cairns
Year: 2013

Reference:

Armstrong RA, Kotzbauer PT, Perlmutter JS, Campbell MC, Hurth KM, Schmidt RE, Cairns NJ. J Neural Transm. 2013 Aug 31. [Epub ahead of print]A quantitative study of Î±-synuclein pathology in fifteen cases of dementia associated with Parkinson disease.PMID:23996276[PubMed – as supplied by publisher]

Name: anne fagan
Year: 2013

Reference:

Benitez BA, Jin SC, Guerreiro R, Graham R, Lord J, Harold D, Sims R, Lambert JC, Gibbs JR, Bras J, Sassi C, Harari O, Bertelsen S, Lupton MK, Powell J, Bellenguez C, Brown K, Medway C, Haddick PC, van der Brug MP, Bhangale T, Ortmann W, Behrens T, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Haines JL, Turton J, Braae A, Barber I, Fagan AM, Holtzman DM, Morris JC; The 3C Study Group, the EADI consortium, the Alzheimer’s Disease Genetic Consortium (ADGC), Alzheimer’s Disease Neuroimaging Initiative (ADNI), the GERAD Consortium, Williams J, Kauwe JS, Amouyel P, Morgan K, Singleton A, Hardy J, Goate AM, Cruchaga C. Missense variant in TREML2 protects against Alzheimer’s disease. Neurobiol Aging. 2013 Dec 21. pii: S0197-4580(13)00649-0. doi: 10.1
PMID:24439484

Name: Alison Goate
Year: 2013

Reference:

Benitez BA, Karch CM, Cai Y, Jin SC, Cooper B, Carrell D, Bertelsen S, Chibnik L, Schneider JA, Bennett DA; Alzheimer’s Disease Neuroimaging Initiative; Genetic and Environmental Risk for Alzheimer’s Disease Consortium GERAD, Fagan AM, Holtzman D, Morris JC, Goate AM, Cruchaga C. The PSEN1, p.E318G variant increases the risk of Alzheimer’s disease in APOE-Îµ4 carriers. PloS Genet 2013; 9(8):e1003685. PMCID: PMC3750021

Name: Anne Fagan
Year: 2013

Reference:

Benitez BA, Karch CM, Cai Y, Jin SC, Cooper B, Carrell D, Bertelsen S, Chibnik L, Schneider JA, Bennett DA; The PSEN1, p.E318G Variant Increases the Risk of Alzheimer’s Disease in APOE-Îµ4 Carriers. Alzheimer’s Disease Neuroimaging Initiative (ADNI); Genetic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD1), Fagan AM, Holtzman D, Morris JC, Goate AM, Cruchaga C. PLoS Genet. 2013 Aug;9(8):e1003685. PMCID: PMC3750021

Name: Alison Goate
Year: 2013

Reference:

Benzinger TL, Blazey T, Jack CR Jr, Koeppe RA, Su Y, Xiong C, Raichle ME, Snyder AZ, Ances BM, Bateman RJ, Cairns NJ, Fagan AM, Goate A, Marcus DS, Aisen PS, Christensen JJ, Ercole L, Hornbeck RC, Farrar AM, Aldea P, Jasielec MS, Owen CJ, Xie X, Mayeux R, Brickman A, McDade E, Klunk W, Mathis CA, Ringman J, Thompson PM, Ghetti B, Saykin AJ, Sperling RA, Johnson KA, Salloway S, Correia S, Schofield PR, Masters CL, Rowe C, Villemagne VL, Martins R, Ourselin S, Rossor MN, Fox NC, Cash DM, Weiner MW, Holtzman DM, Buckles VD, Moulder K, Morris JCRegional variability of imaging biomarkers in autosomal dominant Alzheimer’s disease. Proc Natl Acad Sci 2013; 110(47): E4502-9. PMCID: PMC3839740

Name: anne fagan
Year: 2013

Reference:

Benzinger TL, Blazey T, Jack CR Jr, Koeppe RA, Su Y, Xiong C, Raichle ME, Snyder AZ, Ances BM, Bateman RJ, Cairns NJ, Fagan AM, Goate A, Marcus DS, Aisen PS, Christensen JJ, Ercole L, Hornbeck RC, Farrar AM, Aldea P, Jasielec MS, Owen CJ, Xie X, Mayeux R, Brickman A, McDade E, Klunk W, Mathis CA, Ringman J, Thompson PM, Ghetti B, Saykin AJ, Sperling RA, Johnson KA, Salloway S, Correia S, Schofield PR, Masters CL, Rowe C, Villemagne VL, Martins R, Ourselin S, Rossor MN, Fox NC, Cash DM, Weiner MW, Holtzman DM, Buckles VD, Moulder K, Morris JC. Regional variability of imaging biomarkers in autosomal dominant Alzheimer’s disease. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4502-9. doi: 10.1073/pnas.1317918110. Epub 2013 Nov 5.

PMID:24194552

Name: Nigel Cairns
Year: 2013

Reference:

Benzinger TL, Blazey T, Jack CR Jr, Koeppe RA, Su Y, Xiong C, Raichle ME, Snyder AZ, Ances BM, Bateman RJ, Cairns NJ, Fagan AM, Goate A, Marcus DS, Aisen PS, Christensen JJ, Ercole L, Hornbeck RC, Farrar AM, Aldea P, Jasielec MS, Owen CJ, Xie X, Mayeux R, Brickman A, McDade E, Klunk W, Mathis CA, Ringman J, Thompson PM, Ghetti B, Saykin AJ, Sperling RA, Johnson KA, Salloway S, Correia S, Schofield PR, Masters CL, Rowe C, Villemagne VL, Martins R, Ourselin S, Rossor MN, Fox NC, Cash DM, Weiner MW, Holtzman DM, Buckles VD, Moulder K, Morris JC.Regional variability of imaging biomarkers in autosomal dominant Alzheimer’s disease. Proc Natl Acad Sci U S A. 2013 Nov 5. [Epub ahead of print]
PMID:24194552[PubMed – as supplied by publisher]

Name: Nigel Cairns
Year: 2013

Reference:

Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Jackson G, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian ZS, Sutherland M, Abushakra S, Lewcock J, Farese R, Kenet RO, Laferla F, Perrin S, Whitaker S, Honig L, Mesulam MM, Boeve B, Grossman M, Miller BL, Cummings JL.The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier). Alzheimers Dement. 2013 Mar;9(2):189-98. doi: 10.1016/j.jalz.2012.03.003. 2012 Oct 10.PMC3562382

Name: Nigel Cairns
Year: 2013

Reference:

Campbell MC, Markham J, Flores H, Hartlein JM, Goate AM, Cairns NJ, Videen TO, Perlmutter JS. Principal component analysis of PiB distribution in Parkinson and Alzheimer diseases.
Neurology. 2013 Jul 3.PMC3775684

Name: Nigel Cairns
Year: 2013

Reference:

Cash DM, Ridgway GR, Liang Y, Ryan NS, Kinnunen KM, Yeatman T, Malone IB, Benzinger TL, Jack CR Jr, Thompson PM, Ghetti BF, Saykin AJ, Masters CL, Ringman JM, Salloway SP, Schofield PR, Sperling RA, Cairns NJ, Marcus DS, Xiong C, Bateman RJ, Morris JC, Rossor MN, Ourselin S, Fox NC; Dominantly Inherited Alzheimer Network (DIAN).The pattern of atrophy in familial Alzheimer disease: Volumetric MRI results from the DIAN study. Neurology. 2013 Oct 15;81(16):1425-33. doi: 10.1212/WNL.0b013e3182a841c6. Epub 2013 Sep 18.PMC3806583

Name: Alison Goate
Year: 2013

Reference:

Chapman J, Rees E, Harold D, Ivanov D, Gerrish A, Sims R, Hollingworth P, Stretton A; GERAD1 Consortium, Holmans P, Owen MJ, O’Donovan MC, Williams J, Kirov G. A genome-wide study shows a limited contribution of rare copy number variants to Alzheimer’s disease risk. Hum Mol Genet. 2013; 22(4):816-24. PMCID: PMC3554198

Name: Nigel Cairns
Year: 2013

Reference:

Cheng H, Wang M, Li JL, Cairns NJ, Han X.Specific changes of sulfatide levels in individuals with pre-clinical Alzheimer’s disease: an early event in disease pathogenesis.
J Neurochem. 2013 Jul 18. doi: 10.1111/jnc.12368. [Epub ahead of print]
PMID: 23865640

Name: Alison Goate
Year: 2013

Reference:

Chhatwal JP, Schultz AP, Johnson K, Benzinger TL, Jack C Jr, Ances BM, Sullivan CA, Salloway SP, Ringman JM, Koeppe RA, Marcus DS, Thompson P, Saykin AJ, Correia S, Schofield PR, Rowe CC, Fox NC, Brickman AM, Mayeux R, McDade E, Bateman R, Fagan AM, Goate AM, Xiong C, Buckles VD, Morris JC, Sperling RA. Impaired default network functional connectivity in autosomal dominant Alzheimer disease. Neurology 2013; 81(8):736-744. PMCID: PMC3776464

Name: Anne Fagan
Year: 2013

Reference:

Name: Alison Goate
Year: 2013

Reference:

Cruchaga C, Karch CM, Jin SC, Benitez BA, Cai Y, Guerreiro R, Harari O, Norton J, Budde J, Bertelsen S, Jeng AT, Cooper B, Skorupa T, Carrell D, Levitch D, Hsu S, Choi J, Ryten M; UK Brain Expression Consortium (UKBEC), Hardy J, Ryten M, Trabzuni D, Weale ME, Ramasamy A, Smith C, Sassi C, Bras J, Gibbs JR, Hernandez DG, Lupton MK, Powell J, Forabosco P, Ridge PG, Corcoran CD, Tschanz JT, Norton MC, Munger RG, Schmutz C, Leary M, Demirci FY, Bamne MN, Wang X, Lopez OL, Ganguli M, Medway C, Turton J, Lord J, Braae A, Barber I, Brown K; The Alzheimerâ€™s Research UK (ARUK) Consortium, Passmore P, Craig D, Johnston J, McGuinness B, Todd S, Heun R, KÃ¶lsch H, Kehoe PG, Hooper NM, Vardy ER, Mann DM, Pickering-Brown S, Brown K, Kalsheker N, Lowe J, Morgan K, David Smith A, Wilcock G, Warden D, Holmes C, Pastor P, Lorenzo-Betancor O, Brkanac Z, Scott E, Topol E, Morgan K, Rogaeva E, Singleton AB, Hardy J, Kamboh MI, St George-Hyslop P, Cairns N, Morris JC, Kauwe JS, Goate AM. Rare coding variants in the phospholipase D3 gene confer risk for Alzheimerâ€™s disease. Nature 2014; 505(7484): 550-4. PMID: 24336208

Name: Nigel Cairns
Year: 2013

Reference:

Cruchaga C, Karch CM, Jin SC, Benitez BA, Cai Y, Guerreiro R, Harari O, Norton J, Budde J, Bertelsen S, Jeng AT, Cooper B, Skorupa T, Carrell D, Levitch D, Hsu S, Choi J, Ryten M; UK Brain Expression Consortium, Hardy J, Ryten M, Trabzuni D, Weale ME, Ramasamy A, Smith C, Sassi C, Bras J, Gibbs JR, Hernandez DG, Lupton MK, Powell J, Forabosco P, Ridge PG, Corcoran CD, Tschanz JT, Norton MC, Munger RG, Schmutz C, Leary M, Demirci FY, Bamne MN, Wang X, Lopez OL, Ganguli M, Medway C, Turton J, Lord J, Braae A, Barber I, Brown K; Alzheimerâ€™s Research UK Consortium, Passmore P, Craig D, Johnston J, McGuinness B, Todd S, Heun R, KÃ¶lsch H, Kehoe PG, Hooper NM, Vardy ER, Mann DM, Pickering-Brown S, Brown K, Kalsheker N, Lowe J, Morgan K, David Smith A, Wilcock G, Warden D, Holmes C, Pastor P, Lorenzo-Betancor O, Brkanac Z, Scott E, Topol E, Morgan K, Rogaeva E, Singleton AB, Hardy J, Kamboh MI, St George-Hyslop P, Cairns N, Morris JC, Kauwe JS, Goate AM. Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease. Nature. 2014 Jan 23;505(7484):550-4. doi: 10.1038/nature12825. Epub 2013 Dec 11.

Name: Alison Goate
Year: 2013

Reference:

Cruchaga C, Kauwe JS, Harari O, Jin SC, Cai Y, Karch CM, Benitez BA, Jeng AT, Skorupa T, Carrell D, Bertelsen S, Bailey M, McKean D, Shulman JM, De Jager PL, Chibnik L, Bennett DA, Arnold SE, Harold D, Sims R, Gerrish A, Williams J, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Peskind ER, Galasko D, Fagan AM, Holtzman DM, Morris JC; GERAD Consortium; Alzheimerâ€™s Disease Neuroimaging Initiative (ADNI); Alzheimer Disease Genetic Consortium (ADGC), Goate AM. GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease. Neuron. 2013; 78(2):256-68. PMCID: PMC3664945

Name: Anne Fagan
Year: 2013

Reference:

Name: david balota
Year: 2013

Reference:

Duchek JM, Balota DA, Thomas JB, Snyder AZ, Rich P, Benzinger TL, Ances BM. Relationship between Stroop performance and resting state functional connectivity in cognitively normal older adults. Neuropsychology 2013; 27: 516-528. PMCID: PMC3837537.

Name: Anne Fagan
Year: 2013

Reference:

Duchek JM, Balota DA, Thomas JB, Snyder AZ, Rich P, Benzinger TL, Fagan AM, Holtzman DM, Morris JC, Ances BM. Relationship between Stroop performance and resting state functional connectivity in cognitively normal older adults. Neuropsychology. 2013 Sep;27(5):516-28. PMID: 24040929 [PubMed – in process]

Name: Janet Duchek
Year: 2013

Reference:

Name: Nigel Cairns
Year: 2013

Reference:

Esparza TJ, Zhao H, Cirrito JR, Cairns NJ, Bateman RJ, Holtzman DM, Brody DL.Amyloid-beta oligomerization in Alzheimer dementia versus high-pathology controls. Ann Neurol. 2013 Jan;73(1):104-19. doi: 10.1002/ana.23748. Epub 2012 Dec 7.PMC3563737

Name: Anne Fagan
Year: 2013

Reference:

Fagan AM, Vos SJ. Preclinical Alzheimer’s disease criteria. Lancet Neurol. 2013 Sep 6. doi:pii: S1474-4422(13)70222-9. 10.1016/S1474-4422(13)70222-9. [Epub ahead of print] No abstract available. PMID: 24025450 [PubMed – as supplied by publisher]

Name: Anne Fagan
Year: 2013

Reference:

Fagan AM. Fluid biomarkers for Alzheimer’s disease. In: Neurobiology of Mental Illness, 4th Ed., 2013, Oxford University Press: New York, pp. 834-43.

Name: Alison Goate
Year: 2013

Reference:

Frost SM, Kanagasingam Y, Sohrabi HR, Taddei K, Bateman R, Morris J, Benzinger T, Goate A, Masters CL, Martins RN. Pupil Response Biomarkers Distinguish Amyloid Precursor Protein Mutation Carriers from Non-Carriers. Curr Alzheimer Res. 2013; 10(8): 790-6. PMCID: PMC3879087

Name: Brian Gordon
Year: 2013

Reference:

Gordon, BA, Blazey T, Benzinger, TLS, Head, D. Effects of Aging and Alzheimerâ€™s Disease Along the Longitudinal Axis of the Hippocampus. Journal of Alzheimerâ€™s Disease 2013; 37(1): 41-50

Name: Alison Goate
Year: 2013

Reference:

Guerreiro R, Wojtas A, Bras J, Carrasquillo M, Rogaeva E, Majounie E, Cruchaga C, Sassi C, Kauwe J, Younkin S, Hazrati L, Collinge J, Pocock J, Lashley T, Williams J, Lambert JC, Amouyel P, Goate A, Rademakers R, Morgan K, Powell J, St. George-Hyslop P, Singleton A, Hardy J for the Alzheimer Genetic Analysis Group*. TREM2 Variants in Alzheimerâ€™s Disease NEJM 2013; 368 (2): 117-127. PMCID: PMC3631573

Name: Nigel Cairns
Year: 2013

Reference:

Harms M, Benitez BA, Cairns N, Cooper B, Cooper P, Mayo K, Carrell D, Faber K, Williamson J, Bird T, Diaz-Arrastia R, Foroud TM, Boeve BF, Graff-Radford NR, Mayeux R, Chakraverty S, Goate AM, Cruchaga C; NIA-LOAD/NCRAD Family Study Consortium. C9orf72 hexanucleotide repeat expansions in clinical Alzheimer disease. JAMA Neurol. 2013 Jun 1;70(6):736-41. doi: 10.1001/2013.jamaneurol.537.
NIHMS469368

Name: Alison Goate
Year: 2013

Reference:

Holmans P, Moskvina V, Jones L, Sharma M; International Parkinson’s Disease Genomics Consortium (IPDGC), Vedernikov A, Buchel F, Sadd M, Bras JM, Bettella F, Nicolaou N, SimÃ³n-SÃ¡nchez J, Mittag F, Gibbs JR, Schulte C, Durr A, Guerreiro R, Hernandez D, Brice A, StefÃ¡nsson H, Majamaa K, Gasser T, Heutink P, Wood NW, Martinez M, Singleton AB, Nalls MA, Hardy J, Morris HR, Williams NM. A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson’s disease. Hum Mol Genet. 2013; 22(5):1039-49. PMCID: PMC3561909

Name: Alison Goate
Year: 2013

Reference:

Holton P, Ryten M, Nalls M, Trabzuni D, Weale ME, Hernandez D, Crehan H, Gibbs JR, Mayeux R, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD; Alzheimer’s Disease Genetics Consortium, Ramirez-Restrepo M, Engel A, Myers AJ, Corneveaux JJ, Huentelman MJ, Dillman A, Cookson MR, Reiman EM, Singleton A, Hardy J, Guerreiro R, Apostolova LG, Arnold SE, Baldwin CT, Barber R, Barmada MM, Beach TG, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buros J, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carrasquillo MM, Carroll SL, Chui HC, Clark DG, Cotman CW, Crane PK, Crocco EA, Cruchaga C, Cummings JL, De Jager PL, DeCarli C, DeKosky ST, Demirci FY, Diaz-Arrastia R, Dick M, Dickson DW, Duara R, Ellis WG, Ertekin-Taner N, Evans D, Faber KM, Fallon KB, Farlow MR, Ferris S, Foroud TM, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Goate AM, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Kamboh MI, Karlawish J, Karydas A, Kauwe JS, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer P, Kukull WA, Lah JJ, Larson EB, Levey AI, Lieberman AP, Lopez OL, Lunetta KL, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Naj AC, Nowotny P, Parisi JE, Peskind E, Petersen RC, Poon WW, Potter H, Quinn JF, Raj A, Rajbhandary RA, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Shelanski ML, Smith CD, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Tsuang DW, Valladares O, Van Deerlin VM, Vardarajan BN, Vinters HV, Vonsattel JP, Wang LS, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Wright CB, Younkin SG. Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk lock. Ann Hum Genet. 2013; 77(2):85-105. PMCID: PMC3578142

Name: Nigel Cairns
Year: 2013

Reference:

Holton P, Ryten M, Nalls M, Trabzuni D, Weale ME, Hernandez D, Crehan H, Gibbs JR, Mayeux R, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD; Alzheimer’s Disease Genetics Consortium, Ramirez-Restrepo M, Engel A, Myers AJ, Corneveaux JJ, Huentelman MJ, Dillman A, Cookson MR, Reiman EM, Singleton A, Hardy J, Guerreiro R, Apostolova LG, Arnold SE, Baldwin CT, Barber R, Barmada MM, Beach TG, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buros J, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carrasquillo MM, Carroll SL, Chui HC, Clark DG, Cotman CW, Crane PK, Crocco EA, Cruchaga C, Cummings JL, De Jager PL, DeCarli C, DeKosky ST, Demirci FY, Diaz-Arrastia R, Dick M, Dickson DW, Duara R, Ellis WG, Ertekin-Taner N, Evans D, Faber KM, Fallon KB, Farlow MR, Ferris S, Foroud TM, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Goate AM, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Kamboh MI, Karlawish J, Karydas A, Kauwe JS, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer P, Kukull WA, Lah JJ, Larson EB, Levey AI, Lieberman AP, Lopez OL, Lunetta KL, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Naj AC, Nowotny P, Parisi JE, Peskind E, Petersen RC, Poon WW, Potter H, Quinn JF, Raj A, Rajbhandary RA, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Shelanski ML, Smith CD, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Tsuang DW, Valladares O, Van Deerlin VM, Vardarajan BN, Vinters HV, Vonsattel JP, Wang LS, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Wright CB, Younkin SG.Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci.Ann Hum Genet. 2013 Mar;77(2):85-105. doi: 10.1111/ahg.12000. Epub 2013 Jan 30.PMID:23360175

Name: Nupur Ghoshal
Year: 2013

Reference:

Hurth K, Tarawneh R, Ghoshal N, Benzinger TL, Clifford DB, Geschwind M, Morris JC, Galvin JE, Schmidt RE, Cairns NJ. Whipple’s Disease Masquerades as Dementia With Lewy Bodies. Alzheimer disease and associated disorders. Aug 29 2013. PMCID: PMC3938990
*All contributed equally.

Name: Nigel Cairns
Year: 2013

Reference:

Hurth K, Tarawneh R, Ghoshal N, Benzinger TL, Clifford DB, Geschwind M, Morris JC, Galvin JE, Schmidt RE, Cairns NJ.Whipple’s Disease Masquerades as Dementia With Lewy Bodies. Alzheimer Dis Assoc Disord. 2013 Aug 29. [Epub ahead of print] No abstract available.
PMID:23995819[PubMed – as supplied by publisher]

Name: david balota
Year: 2013

Reference:

Jackson JD, Balota DA. Age-related changes in attentional selection: quality of task set or degradation of task set across time? Psychology and Aging 2013; 28: 744-753. PMCID: PMC3979426.

Name: david balota
Year: 2013

Reference:

Jackson JD, Weinstein Y, Balota DA. Can mind-wandering be timeless? Atemporal focus and aging in mind-wandering paradigms. Frontiers in Psychology 2013; 4: 1-16. PMCID: PMC3797394.

Name: Anne Fagan
Year: 2013

Reference:

Ju YE, McLeland JS, Toedebusch CD, Xiong C, Fagan AM, Duntley SP, Morris JC, Holtzman DM. Sleep Quality and Preclinical Alzheimer Disease. JAMA Neurol. 2013 Mar 11:1-7. doi: 10.1001/jamaneurol.2013.2334. [Epub ahead of print]

Name: David Holtzman
Year: 2013

Reference:

Name: Yo-El Ju
Year: 2013

Reference:

Ju Yo-El S, McLeland J, Toedebusch C, Xiong C, Fagan A, Duntley S, Morris J, Holtzman DH. Sleep quality and preclinical Alzheimer Disease. JAMA Neurology. In press.

Name: Alison Goate
Year: 2013

Reference:

Karch CM, Jeng AT, Goate AM. Calcium phosphatase calcineurin influences tau metabolism. Neurobiol Aging. 2013; 34(2):374-86. PMCID: PMC3879081

Name: Nigel Cairns
Year: 2013

Reference:

Klingstedt T, Shirani H, Aslund KO, Cairns NJ, Sigurdson CJ, Goedert M, Nilsson KP.
The Structural Basis for Optimal Performance of Oligothiophene-Based Fluorescent Amyloid Ligands: Conformational Flexibility is Essential for Spectral Assignment of a Diversity of Protein Aggregates. Chemistry. 2013 Jul 29;19(31):10179-92. doi: 10.1002/chem.201301463. Epub 2013 Jun 18.
PMID: 23780508

Name: Alison Goate
Year: 2013

Reference:

Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, Jun G, Destefano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Hollingworth P, Ramirez A, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, MorÃ³n FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, FiÃ©vet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, BossÃ¹ P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F; European Alzheimer’s Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer’s Disease (GERAD); Alzheimer’s Disease Genetic Consortium (ADGC); Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE), Moebus S, Mecocci P, Del Zompo M, Maier W, Hampel H, Pilotto A, Bullido M, Panza F, Caffarra P, Nacmias B, Gilbert JR, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O’Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Wang LS, Dartigues JF, Mayeux R, Tzourio C, Hofman A, NÃ¶then MM, Graff C, Psaty BM, Jones L, Haines JL, Holmans PA, Lathrop M, Pericak-Vance MA, Launer LJ, Farrer LA, van Duijn CM, Van Broeckhoven C, Moskvina V, Seshadri S, Williams J, Schellenberg GD, Amouyel P. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer’s disease. Nat Genet 2013; 45(12):1452-8. PMCID: PMC3896259

Name: Alison Goate
Year: 2013

Reference:

Lee SH, Harold D, Nyholt DR; ANZGene Consortium; International Endogene Consortium; Genetic and Environmental Risk for Alzheimer’s disease Consortium, Goddard ME, Zondervan KT, Williams J, Montgomery GW, Wray NR, Visscher PM. Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer’s disease, multiple sclerosis and endometriosis. Hum Mol Genet. 2013; 22(4):832-41. PMC3554206

Name: Anne Fagan
Year: 2013

Reference:

Mattsson N, Andreasson U, Persson S, Carrillo MC, Collins S, Chalbot S, Cutler N, Dufour-Rainfray D, Fagan AM, Heegaard NH, Robin Hsiung GY, Hyman B, Iqbal K, Lachno DR, LleÃƒÂ³ A, Lewczuk P, Molinuevo JL, Parchi P, Regeniter A, Rissman R, Rosenmann H, Sancesario G, SchrÃƒÂ¶der J, Shaw LM, Teunissen CE, Trojanowski JQ, Vanderstichele H, Vandijck M, Verbeek MM, Zetterberg H, Blennow K, KÃƒÂ¤ser SA; CSF biomarker variability in the AlzheimerÃ¢â‚¬â„¢s Association quality control program
Alzheimer’s Association QC Program Work Group.
Alzheimers Dement. 2013 May;9(3):251-61. PMCID: PMC3707386

Name: Anne Fagan
Year: 2013

Reference:

Mills SM, Mallmann J, Santacruz AM, Fuqua A, Carril M, Aisen PS, Althage MC, Belyew S, Benzinger TL, Brooks WS, Buckles VD, Cairns N.J, Clifford D, Danek A, Fagan AM, Farlow M, Fox N, Ghetti B, Goate AM, Heinrichs D, Hornbeck R, Jack C, Jucker M,. Klunk WE, Marcus DS, Martins RN, Masters CM, Mayeux R, McDade E, Morris JC, Oliver A, Ringman JM, Rossor MN, Salloway S, Schofield PR, Snider J, Snyder P, Sperling RA, Stewart C, Thomas RG, Xiong C, Bateman RJ. Preclinical trials in autosomal dominant AD: Implementation of the DIAN-TU trial. NEUROL-1136; 1-7

Name: Alison Goate
Year: 2013

Reference:

Mills SM, Mallmann J, Santacruz AM, Fuqua A, Carril M, Aisen PS, Althage MC, Belyew S, Benzinger TL, Brooks WS, Buckles VD, Cairns NJ, Clifford D, Danek A, Fagan AM, Farlow M, Fox N, Ghetti B, Goate AM, Heinrichs D, Hornbeck R, Jack C, Jucker M, Klunk WE, Marcus DS, Martins RN, Masters CM, Mayeux R, McDade E, Morris JC, Oliver A, Ringman JM, Rossor MN, Salloway S, Schofield PR, Snider J, Snyder P, Sperling RA, Stewart C, Thomas RG, Xiong C, Bateman RJ. Preclinical trials in autosomal dominant AD: Implementation of the DIAN-TU trial. Rev Neurol (Paris) 2013; 169(10):737-43. PMCID: PMC 3880800

Name: Alison Goate
Year: 2013

Reference:

Miyashita A, Koike A, Jun G, Wang LS, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Ikeuchi T, Nishizawa M, Suga M, Kawase Y, Akatsu H, Kosaka K, Yamamoto T, Imagawa M, Hamaguchi T, Yamada M, Moriaha T, Takeda M, Takao T, Nakata K, Fujisawa Y, Sasaki K, Watanabe K, Nakashima K, Urakami K, Ooya T, Takahashi M, Yuzuriha T, Serikawa K, Yoshimoto S, Nakagawa R, Kim JW, Ki CS, Won HH, Na DL, Seo SW, Mook-Jung I; Alzheimer Disease Genetics Consortium, St George-Hyslop P, Mayeux R, Haines JL, Pericak-Vance MA, Yoshida M, Nishida N, Tokunaga K, Yamamoto K, Tsuji S, Kanazawa I, Ihara Y, Schellenberg GD, Farrer LA, Kuwano R. SORL1 is genetically associated with late-onset Alzheimer’s disease in Japanese, Koreans and Caucasians. PLoS One. 2013; 8(4):e58618. PMCID: PMC3614978

Name: Nupur Ghoshal
Year: 2013

Reference:

Monsell SE, Mock C, Roe CM, Ghoshal N, Morris JC, Cairns NJ, Kukull W. Comparison of symptomatic and asymptomatic persons with Alzheimer disease neuropathology. Neurology. Jun 4 2013;80(23):2121-2129. PMCID: PMC3716351

Name: catherine roe
Year: 2013

Reference:

Monsell SE, Mock C, Roe CM, Ghoshal N, Morris JC, Cairns NJ, Kukull. Comparison of symptomatic and asymptomatic persons with Alzheimerâ€™s disease neuropathology. Neurology (In press).

Name: Anne Fagan
Year: 2013

Reference:

Perrin RJ, Payton JE, Malone JP, Gilmore P, Davis AE, Xiong C, Fagan AM, Townsend RR, Holtzman DM. Quantitative Label-Free Proteomics for Discovery of Biomarkers in Cerebrospinal Fluid: Assessment of Technical and Inter-Individual Variation. PLoS One. 2013 May 20;8(5):e64314. PMCID: PMC3659127

Name: David Holtzman
Year: 2013

Reference:

Perrin RJ, Payton JE, Malone JP, Gilmore P, Davis AE, Xiong C, Fagan AM, Townsend RR, Holtzman DM. Quantitative label-free proteomics for discovery of biomarkers in cerebrospinal fluid: assessment of technical and inter-individual variation.
PLoS One. 2013 May 20;8(5):e64314. doi: 10.1371/journal.pone.0064314. PMCID:PMC3659127

Name: catherine roe
Year: 2013

Reference:

Pizzie R, Hindman H, Roe CM, Head D, Grant E, Morris JC, Hassenstab JJ. Physical Activity and Cognitive Trajectories in Cognitively Normal Aduts: The Adult Children Study. Alzheimerâ€™s Disease & Associated Disorders (In press).

Name: David Holtzman
Year: 2013

Reference:

Potter R, Patterson BW, Elbert DL, Ovod V, Kasten T, Sigurdson W, Mawuenyega K, Blazey T, Goate A, Chott R, Yarasheski KE, Holtzman DM, Morris JC, Benzinger TL, Bateman RJ.
Increased in Vivo Amyloid-Î²42 Production, Exchange, and Loss in Presenilin Mutation Carriers.
Sci Transl Med. 2013 Jun 12;5(189):189ra77. doi: 10.1126/scitranslmed.3005615.

Name: Alison Goate
Year: 2013

Reference:

Potter R, Patterson BW, Elbert DL, Ovod V, Kasten T, Sigurdson W, Mawuenyega K, Blazey T, Goate A, Chott R, Yarasheski KE, Holtzman DM, Morris JC, Benzinger TL, Bateman RJ. Increased in Vivo Amyloid-Î²42 Production, Exchange, and Loss in Presenilin Mutation Carriers. Sci Transl Med 2013; 5(189):189ra77. PMCID: PMC3838868

Name: Alison Goate
Year: 2013

Reference:

Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith P, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hendrie H, Hall KS, Goate AM, Byrd GS, Kukull WA, Foroud TM, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD, Mayeux R; Alzheimer Disease Genetics Consortium. Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E Ïµ4,and the risk of late-onset Alzheimer disease in African Americans. JAMA. 2013; 309(14):1483-92. PMCID:PMC3667653

Name: Alison Goate
Year: 2013

Reference:

Reitz C, Mayeux R; Alzheimerâ€™s Disease Genetics Consortium. TREM2 and neurodegenerative disease. N Engl J Med. 2013; 369(16):1564-5. PMID: 24131184

Name: catherine roe
Year: 2013

Reference:

Roe CM, Behrens MI. AD and cancer: epidemiology makes for strange bedfellows. Neurology (in press).

Name: denise maue dreyfus
Year: 2013

Reference:

Roe CM, Fagan AM, Grant EA, Hassenstab J, Moulder KL, Maue Dreyfus D, Sutphen C, Benzinger TLS, Mintun MA, Holtzman DM, Morris JC. Amyloid imaging and CSF biomarkers in predicting cognitive impairment up to 7.5 years later.
Neurology 2013. 10.1212/WNL.0b013e3182918ca6
Published online before print April 10, 2013

Name: Anne Fagan
Year: 2013

Reference:

Roe CM, Fagan AM, Grant EA, Hassenstab J, Moulder KL, Maue Dreyfus D, Sutphen CL, Benzinger TL, Mintun MA, Holtzman DM, Morris JC. Amyloid imaging and CSF biomarkers in predicting cognitive impairment up to 7.5 years later. Neurology. 2013 Apr 10. [Epub ahead of print] PMID: 23576620 [PubMed – as supplied by publisher]

Name: anne fagan
Year: 2013

Reference:

Roe CM, Fagan AM, Grant EA, Holtzman DM, Morris JC. CSF biomarkers of Alzheimer disease: “noncognitive” outcomes.Neurology. 2013 Dec 3;81(23):2028-31. doi: 10.1212/01.wnl.0000436940.78152.05. Epub 2013 Nov 8.

PMID:24212387

Name: catherine roe
Year: 2013

Reference:

Roe CM, Rentz DM. Alzheimer disease: before the diagnosis / About preclinical Alzheimer Disease. Neurology March 26, 2013 80:e148-e149.

Name: catherine roe
Year: 2013

Reference:

Shim YS, Roe CM, Buckles V, Morris JC. Clinicopathologic Study of Alzheimerâ€™s Disease: Alzheimer mimics. Journal of Alzheimerâ€™s Disease (In press).

Name: Anne Fagan
Year: 2013

Reference:

Stark SL, Roe CM, Grant EA, Hollingsworth H, Benzinger TL, Fagan AM, Buckles VD, Morris JC. Preclinical Alzheimer disease and risk of falls. Neurology. 2013 Jul 30;81(5):437-43. PMCID: PMC3776538

Name: catherine roe
Year: 2013

Reference:

Stark SL, Roe CM, Grant EA, Holly H, Benzinger TL, Fagan AM, Buckles VD, Morris JC. Preclinical Alzheimerâ€™s disease and risk for falls. Neurology (In press).

Name: Anne Fagan
Year: 2013

Reference:

Sutphen CL, Fagan AM, Holtzman DM. Progress update: Fluid and imaging biomarkers in Alzheimerâ€™s disease, Biological Psychiatry, in press

Name: david balota
Year: 2013

Reference:

Thomas AK, Lee M, Balota DA. Metacognitive monitoring and dementia: How intrinsic and extrinsic cues influence judgments of learning in people with early-stage Alzheimerâ€™s disease. Neuropsychology 2013; 27: 452-463. PMCID: PMC4006849.

Name: David Holtzman
Year: 2013

Reference:

Ulrich JD, Burchett JM, Restivo JL, Schuler DR, Verghese PB, Mahan TE, Landreth GE, Castellano JM, Jiang H, Cirrito JR, Holtzman DM. In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis. Mol Neurodegener. 2013 Apr 19;8(1):13. PMCID: PMC3640999

Name: David Holtzman
Year: 2013

Reference:

Veeraraghavalu K, Zhang C, Miller S, Hefendehl JK, Rajapaksha TW, Ulrich J, Jucker M, Holtzman DM, Tanzi RE, Vassar R, Sisodia SS. Comment on “ApoE-directed therapeutics rapidly clear Î²-amyloid and reverse deficits in AD mouse models”. Science. 2013 May 24;340(6135):924-f. doi: 10.1126/science.1235505.

Name: David Holtzman
Year: 2013

Reference:

Verghese PB, Castellano JM, Garai K, Wang Y, Jiang H, Shah A, Bu G, Frieden C, Holtzman DM. ApoE influences amyloid-Î² (AÎ²) clearance despite minimal apoE/AÎ² association in physiological conditions. Proc Natl Acad Sci U S A. 2013 2013 May 7:110(19):E1807-16. PMCID: PMC3651443

Name: David Holtzman
Year: 2013

Reference:

Name: Nigel Cairns
Year: 2013

Reference:

Vos SJ, Xiong C, Visser PJ, Jasielec MS, Hassenstab J, Grant EA, Cairns NJ, Morris JC, Holtzman DM, Fagan AM.Preclinical Alzheimer’s disease and its outcome: a longitudinal cohort study.Lancet Neurol. 2013 Oct;12(10):957-65. doi: 10.1016/S1474-4422(13)70194-7. Epub 2013 Sep 4.PMID:24012374

Name: Anne Fagan
Year: 2013

Reference:

Vos SJB, Xiong C, Visser PJ, Jasielec M, Hassenstab J, Grant EA, Cairns NJ, Morris JC, Holtzman DM, Fagan AM, Preclinical Alzheimerâ€™s disease and its outcome: a longitudinal cohort study, Lancet Neurology, in press

Name: Anne Fagan
Year: 2013

Reference:

Wang L, Brier MR, Snyder AZ, Thomas JB, Fagan AM, Xiong C, Benzinger TL, Holtzman DM, Morris JC, Ances BM. Cerebrospinal Fluid AÎ²42, Phosphorylated Tau181, and Resting-State Functional Connectivity. JAMA Neurol. 2013 Aug 19. doi: 10.1001/jamaneurol.2013.3253. [Epub ahead of print] PMID: 23959173 [PubMed – as supplied by publisher]

Name: Nigel Cairns
Year: 2013

Reference:

Weiner MW, Veitch DP, Aisen PS, Beckett LA, Cairns NJ, Green RC, Harvey D, Jack CR, Jagust W, Liu E, Morris JC, Petersen RC, Saykin AJ, Schmidt ME, Shaw L, Shen L, Siuciak JA, Soares H, Toga AW, Trojanowski JQ; Alzheimer’s Disease Neuroimaging Initiative.The Alzheimer’s Disease Neuroimaging Initiative: a review of papers published since its inception.Alzheimers Dement. 2013 Sep;9(5):e111-94. doi: 10.1016/j.jalz.2013.05.1769. Epub 2013 Aug 7. PMID:23932184

Name: Anne Fagan
Year: 2013

Reference:

Winer L, Srinivasan D, Chun S, Lacomis D, Jaffa M, Fagan A, Holtzman DM, Wancewicz E, Bennett CF, Bowser R, Cudkowicz M, Miller TM. SOD1 in cerebral spinal fluid as a pharmacodynamic marker for antisense oligonucleotide therapy. JAMA Neurol. 2013 Feb;70(2):201-7. Doi 10.1001/jamaneurol.2013.593. PMID: 23147550 [PubMed – indexed for MEDLINE]

Name: Alison Goate
Year: 2013

Reference:

Zou F, Belbin O, Carrasquillo MM, Culley OJ, Hunter TA, Ma L, Bisceglio GD, Allen M, Dickson DW, Graff-Radford NR, Petersen RC; Genetic and Environmental Risk for Alzheimerâ€™s disease (GERAD1) Consortium, Morgan K, Younkin SG. Linking protective GAB2 variants, increased cortical GAB2 expression and decreased Alzheimer’s disease pathology. PLoS One 2013: 8(5):e64802. PMCID: PMC3665686

Name: Beau Ances
Year: 2012

Reference:

Ances BM, Benzinger TL, Christensen JJ, Thomas J, Venkat R, Teshome M, Aldea P, Fagan AM, Holtzman DM, Morris JC, Clifford DB. 11C-PiB imaging of human immunodeficiency virus-associated neurocognitive disorder. Arch Neurol. 2012 Jan;69(1):72-7. PMCID: PMC3536500.

Name: Anne Fagan
Year: 2012

Reference:

Name: Anne Fagan
Year: 2012

Reference:

Name: Beau Ances
Year: 2012

Reference:

Ances, B.M., Benzinger, T.L., Christensen, J.J., Thomas, J., Venkat, R., Teshome, M., Aldea, P., Fagan, A.M., Holtzman D.M., Morris, J.C., Clifford, D.B. (2012) HIV Associated Neurocognitive Disorder (HAND) is Not Associated with Increased Fibrillar Amyloid Deposits Using 11C-PiB in Middle-Aged HIV+ Participants. Arch Neurol., 69(1):72-7. PMCID: PMC3536500

Name: Nigel Cairns
Year: 2012

Reference:

Armstrong RA, Cairns NJ. Different molecular pathologies result in similar spatial patterns of cellular inclusions in neurodegenerative disease: a comparative study of eight disorders. J Neural Transm. 2012 Jun 8. [Epub ahead of print]
PMID: 22678700

Name: Jeffrey Zacks
Year: 2012

Reference:

Bailey, H. R., Zacks, J. M., Hambrick, D. Z., Zacks, R. T., Head, D., Kurby, C. A., & Sargent, J. Q. (in press). Medial temporal lobe volume predicts elders’ everyday memory. Psychological Science.

Name: David Balota
Year: 2012

Reference:

Bangert AS, Abrams RA, Balota DA. Reaching for words and nonwords: Interactive effects of word frequency and stimulus quality on the characteristics of reaching movements. Psychonomic Bulletin & Review 2012; 19(3): 513-520. PMID: 22419404. [PubMed – as supplied by publisher]

Name: David Balota
Year: 2012

Reference:

Bangert AS, Balota DA. Keep up the Pace: Declines in simple repetitive timing differentiates healthy aging from the earliest stages of Alzheimer’s disease. Journal of the International Neuropsychological Society 2012; 18(6): 1052-1063. PMCID: PMC3505757.

Name: Anne Fagan
Year: 2012

Reference:

Bateman R, Xiong C, Benzinger T, Fagan A, Goate A, Fox N, Marcus D, Cairns N, Xie X, Blazey T, Holtzman D, Santacruz A, Buckles V, Oliver A, Moulder K, Ghetti B, Klunk W, McDade E, Martins R, Masters C, Mayeux R, Ringman J, Rossor M, Schofield P, Sperling R, Salloway S, Morris J and on behalf of the Dominantly Inherited Alzheimer Network (DIAN) Clinical, cognitive, and biomarker changes in the Dominantly Inherited Alzheimer Network). New England Journal of Medicine 2012, Jul 11. PMCID: PMC3474597

Name: Nigel Cairns
Year: 2012

Reference:

Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TM, Holtzman DM, Santacruz A, Buckles V, Oliver A, Moulder K, Aisen PS, Ghetti B, Klunk WE, McDade E, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Schofield PR, Sperling RA, Salloway S, Morris JC; Dominantly Inherited Alzheimer Network. Clinical and biomarker changes in dominantly inherited Alzheimer’s disease. N Engl J Med. 2012 Aug 30;367(9):795-804. Epub 2012 Jul 11. Erratum in: N Engl J Med. 2012 Aug 23;367(8):780. PMC3474597

Name: Catherine Roe
Year: 2012

Reference:

Behrens MI, Silva M, Salech F, Merino D, Ponce DP, Sinning M, Xiong C, Roe CM, Quest AFG. Journal of Gerontology: Biological Sciences. (In press).

Name: Anne Fagan
Year: 2012

Reference:

Blennow K, Zetterberg H, Fagan A. Fluid biomarkers in AD. In: Biology of AD, Selkoe D, Holtzman D, Mandelkow E, eds., Cold Spring Harbor Laboratory Press: New York, pgs. 91-113, 2012.

Name: Nigel Cairns
Year: 2012

Reference:

Boxer AL, Gold M, Huey E, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian Z, Sutherland M, Farese R, Miller BL, Cummings J. Frontotemporal degeneration, the next therapeutic frontier: Molecules and animal models for frontotemporal degeneration drug development.Alzheimers Dement. 2012 Oct 5. pii: S1552-5260(12)01750-5. PMID:23043900

Name: Nigel Cairns
Year: 2012

Reference:

Boxer AL, Gold M, Huey E, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian Z, Sutherland M, Farese R, Miller BL, Cummings J.Frontotemporal degeneration, the next therapeutic frontier: Molecules and animal models for frontotemporal degeneration drug development. Alzheimers Dement. 2012 Oct 5. doi:pii: S1552-5260(12)01750-5. 10.1016/j.jalz.2012.03.002. PMC3542408

Name: Nigel Cairns
Year: 2012

Reference:

Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Jackson G, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian ZS, Sutherland M, Abushakra S, Lewcock J, Farese R, Kenet RO, Laferla F, Perrin S, Whitaker S, Honig L, Mesulam MM, Boeve B, Grossman M, Miller BL, Cummings JL. The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: The next therapeutic frontier).Alzheimers Dement. 2012 Oct 9. pii: S1552-5260(12)01751-7. PMID:23062850

Name: alison goate
Year: 2012

Reference:

Cruchaga C, Chakraverty S, Mayo K, Vallania FL, Mitra RD, Faber K, Williamson J, Bird T, Diaz-Arrastia R, Foroud TM, Boeve BF, Graff-Radford NR, St Jean P, Lawson M, Ehm MG, Mayeux R, Goate AM; for the NIA-LOAD/NCRAD Family Study Consortium. Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer’s Disease Families. PLoS One. 2012; 7(2):e31039. PMCID: 3270040

Name: Anne Fagan
Year: 2012

Reference:

Cruchaga C, Kauwe JS, Nowotny P, Bales K, Pickering EH, Mayo K, Bertelsen S, Hinrichs A; the AlzheimerÃ¢â‚¬â„¢s Disease Neuroimaging Initiative, Fagan AM, Holtzman DM, Morris JC, Goate AM. Cerebrospinal fluid APOE levels, an endophenotype for genetic studies for Alzheimer’s disease. Human Molecular Genetics. 2012 Jul 20. PMCID:PMC3459471

Name: Yvette Sheline
Year: 2012

Reference:

Disabato BM, Hranilovich J, Morris C, D’Angelo G, Wu N, Doraiswamy PM, and Sheline YI. A Comparison of Brain Structural Variables, Neuropsychological Factors, and Treatment Outcome in Early Versus Late Onset Late Life Depression. The American Journal of Geriatric Psychiatry. In press.

Name: Brianne Disabato
Year: 2012

Reference:

Disabato BM, Sheline YI. Biological Basis of Late Life Depression. Curr Psychiatry Rep. 2012 May 6

Name: Nigel Cairns
Year: 2012

Reference:

Dopamine D1, D2, D3 receptors, vesicular monoamine transporter type-2 (VMAT2) and dopamine transporter (DAT) densities in aged human brain.Sun J, Xu J, Cairns NJ, Perlmutter JS, Mach RH.PLoS One. 2012;7(11):e49483. doi: 10.1371/journal.pone.0049483. Epub 2012 Nov 21.PMC3504049

Name: Anne Fagan
Year: 2012

Reference:

Fagan AM, Perrin RJ; Upcoming candidate cerebrospinal fluid biomarkers of Alzheimer’s disease Biomarkers in Medicine. 2012 Aug;6(4):455-76 PMID: 22917147 PMCID: PMC3477809

Name: Anne Fagan
Year: 2012

Reference:

Fagan AM, Perrin RJ; Upcoming candidate cerebrospinal fluid biomarkers of Alzheimer’s disease Biomarkers in Medicine. 2012 Aug;6(4):455-76 PMID: 22917147 PMCID: PMC3477809

Name: alison goate
Year: 2012

Reference:

Gerrish A, Russo G, Richards A, Moskvina V, Ivanov D, Harold D, Sims R, Abraham R, Hollingworth P, Chapman J, Hamshere M, Pahwa JS, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Johnston JA, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, KÃ¶lsch H, Heun R, SchÃ¼rmann B, Bussche HV, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, FrÃ¶lich L, Hampel H, HÃ¼ll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Davies G, Harris SE, Starr JM, Deary IJ, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, MÃ¼hleisen TW, NÃ¶then MM, Moebus S, JÃ¶ckel KH, Klopp N, Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Jones L, Holmans PA, O’Donovan MC, Owen MJ, Williams J. The Role of Variation at AÎ²PP, PSEN1, PSEN2, and MAPT in Late Onset Alzheimer’s Disease. J Alzheimers Disease 2012; 28(2): 377-87.

Name: Nupur Ghoshal
Year: 2012

Reference:

Ghoshal, N., J.T. Dearborn, D.F. Wozniak, and N.J. Cairns, Core features of frontotemporal dementia recapitulated in progranulin knockout mice. Neurobiol Dis, 2012. 45(1): p. 395-408. PMCID 3225509.

Name: alison goate
Year: 2012

Reference:

Goate A, Hardy J. Twenty years of Alzheimer’s disease-causing mutations. J Neurochem. 2012; 120 Suppl 1:3-8.

Name: Nigel Cairns
Year: 2012

Reference:

Halliday G, Bigio EH, Cairns NJ, Neumann M, Mackenzie IR, Mann DM. Mechanisms of disease in frontotemporal lobar degeneration: gain of function versus loss of function effects. Acta Neuropathol. 2012 Sep;124(3):373-82. Epub 2012 Aug 10.PMID: 22878865

Name: Nigel Cairns
Year: 2012

Reference:

Halliday G, Bigio EH, Cairns NJ, Neumann M, Mackenzie IR, Mann DM.Mechanisms of disease in frontotemporal lobar degeneration: gain of function versus loss of function effects.
Acta Neuropathol. 2012 Sep;124(3):373-82. doi: 10.1007/s00401-012-1030-4. Epub 2012 Aug 10. Review.PMC3445027

Name: Anne Fagan
Year: 2012

Reference:

Hata S, Taniguchi M, Piao Y, Ikeuchi T, Fagan AM, Holtzman DM, Bateman R, Sohrabi HR, Martins RN, Gandy S, Urakami K, Suzuki T; Japanese Alzheimer’s Disease Neuroimaging Initiative. Multiple Î³-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer’s disease subjects. Mol Neurodegener. 2012 Apr 25;7:16. PMCID: PMC3422204

Name: alison goate
Year: 2012

Reference:

Head D, Bugg JM, Goate AM, Fagan AM, Mintun MA, Benzinger T, Holtzman DM, Morris JC.
Exercise Engagement as a Moderator of the Effects of APOE Genotype on Amyloid Deposition.
Arch Neurol. 2012 Jan 9. [Epub ahead of print]

Name: Anne Fagan
Year: 2012

Reference:

Head D, Bugg JM, Goate AM, Fagan AM, Mintun MA, Benzinger T, Holtzman DM, Morris JC. Exercise engagement as a moderator of the effects of APOE genotype on amyloid deposition. Archives of Neurology, 2012; Jan 9 43 PMCID: PMC3583203

Name: Denise Head
Year: 2012

Reference:

Head, D., Bugg, J. M., Goate, A. M., Fagan, A. M., Mintun, M. A., Holtzman, D. M., Morris, J. C. (in press). Exercise engagement as a moderator of APOE effects on amyloid deposition. Archives of Neurology. PMID: 22232206

Name: Anne Fagan
Year: 2012

Reference:

Hu WT, Holtzman DM, Fagan AM, Shaw LM, Perrin R, Arnold SE, Grossman M, Xiong C, Craig-Schapiro R, Clark CM, Pickering E, Kuhn M, Chen Y, Van Deerlin VM, McCluskey L, Elman L, Karlawish J, Chen-Plotkin A, Hurtig HI, Siderowf A, Swenson F, Lee VM, Morris JC, Trojanowski JQ, Soares H; For the Alzheimer’s Disease Neuroimaging Initiative. Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease. Neurology. 2012 Aug 28. PMCID: PMC3425844

Name: Randall bateman
Year: 2012

Reference:

Huang Y, Potter R, Sigurdson W, Santacruz A, Shih S, Ju Y, Kasten T, Morris JC, Mintun M, Duntley S, Bateman RJ. Amyloid-Î² Dynamics are Normal and Decline with Age and Amyloid Deposition. Archives of Neurology 2012; 69:51-58. PMCID: PMC3254706.

Name: Denise Head
Year: 2012

Reference:

Jackson J. D., Balota, D. A., Duchek, J. M., Head, D. (2012). White matter integrity and intraindividual variability in aging and early-stage Alzheimerâ€™s disease. Neuropsychologia, 50, 357-366. PMID: 22172547

Name: David Balota
Year: 2012

Reference:

Jackson JD, Balota DA, Duchek JM, Head D. White matter integrity and reaction time intraindividual variability in healthy aging and early-stage Alzheimer disease. Neuropsychologia 2012; 50(3): 357-366. PMCID: PMC3302689.

Name: David Balota
Year: 2012

Reference:

Jackson JD, Balota DA. Mind-wandering in younger and older adults: Converging evidence from the sustained attention to response task and reading for comprehension. Psychology And Aging 2012; 27(1): 106-119. PMID:22419404.

Name: Alison Goate
Year: 2012

Reference:

Karch CM, Jeng AT, Nowotny P, Cady J, Cruchaga C, Goate AM. Expression of novel Alzheimer’s disease risk genes in control and Alzheimer’s disease brains. PLoS One. 2012; 7(11):e50976. PMCID: PMC3511432

Name: Nigel Cairns
Year: 2012

Reference:

Kotzbauer PT, Cairns NJ, Campbell MC, Willis AW, Racette BA, Tabbal SD, Perlmutter JS.Pathologic Accumulation of Î±-Synuclein and AÎ² in Parkinson Disease Patients With Dementia. Arch Neurol. 2012 Jul 23:1-6. doi: 10.1001/archneurol.2012.1608. [Epub ahead of print]
PMID:
22825369

Name: Nigel Cairns
Year: 2012

Reference:

Laminar Distribution of the Pathological Changes in Sporadic Frontotemporal Lobar Armstrong RA, Hamilton RL, Mackenzie IR, Hedreen J, Cairns NJ. Degeneration with TDP-43 Proteinopathy: A Quantitative Study Using Polynomial Curve Fitting. Neuropathol Appl Neurobiol. 2012 Jul 16. doi: 10.1111/j.1365-2990.2012.01291.x.PMC3504185

Name: David Balota
Year: 2012

Reference:

Maddox GB, Balota DA. Self control of when and how much to test face-name pairs in a novel spaced retrieval paradigm: An examination of age-related differences. Aging, Neuropsychology, and Cognition 2012; 19(5): 620-643. PMCID: PMC3435448.

Name: Marta Cortes-Canteli
Year: 2012

Reference:

Marta Cortes-Canteli, Daria Zamolodchikov, Hyung Jin Ahn, Sidney Strickland and Erin H. Norris. Fibrinogen and Altered Hemostasis in Alzheimerâ€™s Disease. Journal of Alzheimerâ€™s Disease 32 (2012) 599â€“608. PMID:22869464

Name: Yvette Sheline
Year: 2012

Reference:

Mettenburg JM, Benzinger TL, Shimony JS, Snyder AZ, Sheline YI. Diminished performance on neuropsychological testing in late life depression is correlated with microstructural white matter abnormalities. Neuroimage. 2012 May 1;60(4):2182-2190. PMID:22487548

Name: Anne Fagan
Year: 2012

Reference:

Reiman EM, Quiroz YT, Fleisher AS, Chen K, Velez-Pardo C, Jimenez-Del-Rio M, Fagan AM, Shah AR, Alvarez S, Arbelaez A, Giraldo M, Acosta-Baena N, Sperling RA, Dickerson B, Stern CE, Tirado V, Munoz C, Reiman RA, Huentelman MJ, Alexander GE, Langbaum JB, Kosik KS, Tariot PN, Lopera F. Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer’s disease in the presenilin 1 E280A kindred: a case-control study. Lancet Neurol. 2012 Dec;11(12):1048-56. doi: 10.1016/S1474-4422(12)70228-4. Epub 2012 Nov 6.PMID: 23137948 [PubMed – indexed for MEDLINE]

Name: David Holtzman
Year: 2012

Reference:

Roh JH, Huang Y, Bero AW, Kasten T, Stewart FR, Bateman RJ, Holtzman DM.
Disruption of the sleep-wake cycle and diurnal fluctuation of amyloid-Î² in mice with Alzheimerâ€™s disease pathology. Science Translational Medicine 2012 Sep 5;4(150):150ra122.

Name: Brian Carpenter
Year: 2012

Reference:

Saini, R., Preety, A., & Carpenter, B.D. (2012). Nurses and Alzheimerâ€™s disease: A holistic perspective. Indian Journal of Public Health, 56, 318-319. doi:10.4103/0019-557X.106424

Name: Erin Sakai
Year: 2012

Reference:

Sakai EY, Carpenter BD, Rieger RE. “What’s Wrong with Grandma?”: Depictions of Alzheimer’s Disease in Childrenâ€™s Storybooks. American Journal of Alzheimer’s disease and Other Dementias. In Press.

Name: Brian Carpenter
Year: 2012

Reference:

Sakai, E.Y., & Carpenter, B.D. (2012). â€œWhatâ€™s wrong with grandma?â€: Depictions of Alzheimerâ€™s disease in childrenâ€™s storybooks. American Journal of Alzheimer’s Disease and Other Dementias, 27, 586-593. doi:10.1177/1533317512459796

Name: Brianne Disabato
Year: 2012

Reference:

Sheline YI, Disabato BM, Hranilovich J, Morris C, D’Angelo G, Pieper C, Toffanin T, Taylor WD, Macfall JR, Wilkins C, Barch DM, Welsh-Bohmer KA, Steffens DC, Krishnan RR, Doraiswamy PM. Treatment Course With Antidepressant Therapy in Late-Life Depression. Am J Psychiatry. 2012 Oct 3.

Name: Yvette Sheline
Year: 2012

Reference:

Sheline YI, Disabato BM, Hranilovich J, Morris C, D’Angelo GM, Pieper C, Toffanin T, Taylor WD, MacFall JR, Wilkins C, Barch DM, Welsh-Bohmer KA, Steffens DC, Krishnan RR, Doraiswamy PM. Rate of Recovery with Antidepressant Treatment in Late Life Depression. American Journal of Psychiatry, Oct (2012). PMID: 23034601

Name: alison goate
Year: 2012

Reference:

Shi H, Belbin O, Medway C, Brown K, Kalsheker N, Carrasquillo M, Proitsi P, Powell J, Lovestone S, Goate A, Younkin S, Passmore P; Genetic and Environmental Risk for Alzheimer’s Disease (GERAD1) Consortium, Morgan K; Alzheimer’s Research UK (ARUK) Consortium. Genetic variants influencing human aging from late-onset Alzheimer’s disease (LOAD) genome-wide association studies (GWAS). Neurobiol Aging. 2012 Mar 23. [Epub ahead of print]

Name: Susan Stark
Year: 2012

Reference:

Stark SL, Roe CM, Grant E, Hollingsworth H, Benzinger TL, Fagan AM, Buckles VD, Morris JC. Preclinical Alzheimer’s disease and risk for falls. Neurology. In Press 2013.

Name: Anne Fagan
Year: 2012

Reference:

Storandt M, Head D, Fagan AM, Holtzman DM, Morris JC. Toward a multifactorial model of Alzheimer disease. Neurobiology of Aging, 2012 33:2262-71. PMCID: PMC3334456

Name: Anne Fagan
Year: 2012

Reference:

Storandt M, Head D, Fagan AM, Holtzman DM, Morris JC. Toward a multifactorial model of Alzheimer disease. Neurobiology of Aging, 2012 Jan 17. PMCID: PMC3334456

Name: Alison Goate
Year: 2012

Reference:

Whitcomb DC, Larusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L; Alzheimer’s Disease Genetics Consortium, Albert MS, Albin RL, Apostolova LG, Arnold SE, Baldwin CT, Barber R, Barnes LL, Beach TG, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boxer A, Burke JR, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carney RM, Carroll SL, Chui HC, Clark DG, Cribbs DH, Crocco EA, Cruchaga C, Decarli C, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Faber KM, Fallon KB, Farlow MR, Ferris S, Foroud TM, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Glass JD, Goate AM, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hamilton-Nelson KL, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Jun G, Kamboh MI, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, Kramer P, Kukull WA, Laferla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lin CF, Lieberman AP, Lopez OL, Lunetta KL, Lyketsos CG, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Murrell JR, Naj AC, Olichney JM, Parisi JE, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Tsuang DW, Valladares O, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Wang LS, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Conwell D, CotÃ© GA, Cotton PB, Disario J, Farrer LA, Forsmark CE, Johnstone M, Gardner TB, Gelrud A, Greenhalf W, Haines JL, Hartman DJ, Hawes RA, Lawrence C, Lewis M, Mayerle J, Mayeux R, Melhem NM, Money ME, Muniraj T, Papachristou GI, Pericak-Vance MA, Romagnuolo J, Schellenberg GD, Sherman S, Simon P, Singh VP, Slivka A, Stolz D, Sutton R, Weiss FU, Wilcox CM, Zarnescu NO, Wisniewski SR, O’Connell MR, Kienholz ML, Roeder K, Barmada MM, Yadav D, Devlin B. Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet. 2012; 44(12):1349-54. PMCID: PMC3510344

Name: Catherine Roe
Year: 2012

Reference:

Williams MM, Storandt M, Roe CM, Morris JC. Progression of Alzheimer Dementia as Measured by Clinical Dementia Rating Sum of Boxes Scores. Alzheimerâ€™s & Dementia (In press).

Name: Anne Fagan
Year: 2012

Reference:

Winer L, Srinivasan D, Chun S, Lacomis D, Jaffa M, Fagan A, Holtzman DM, Wancewicz E, Bennett CF, Bowser R, Cudkowicz M, Miller T. Cerebrospinal fluid defines SOD1 as a pharmacodynamic marker for antisense oligonucleotide therapy. Archives of Neurology, 2012. PMCID: PMC3812918

Name: Anne Fagan
Year: 2012

Reference:

Winer L,Srinivasan D, Chun S, Lacomis D, Jaffa M, Fagan A, Holtzman DM, Wancewicz E, Bennett CF, Bowser R, Cudkowicz M, Miller T. Cerebrospinal fluid defines SOD1 as a pharmacodynamic marker for antisense oligonucleotide therapy. Archives of Neurology, 2012. PMCID: PMC3812918

Name: Catherine Roe
Year: 2012

Reference:

Yang YH, Roe CM, Morris JC. Relationships between late-life hypertension, blood pressure, and Alzheimerâ€™s disease. American Journal of Alzheimers Disease & Other Dementias. (In press).

Name: David Balota
Year: 2012

Reference:

Yap MJ, Balota DA, Sibley DE, Ratcliff R. Individual differences in visual word recognition: Insights from the English Lexicon Project. Journal Of Experimental Psychology: Human Perception And Performance 2012; 38(1): 53-79. PMCID: PMC3193910.

Name: Brian Carpenter
Year: 2012

Reference:

Zaleta AK, Carpenter BD, Porensky EK, Xiong C, & Morris JC. Agreement about diagnosis among patients, companions, and professionals following a dementia evaluation. Alzheimerâ€™s Disease and Associated Disorders In Press.

Name: Lisa Taylor-Reinwald
Year: 2011

Reference:

Armstrong, R.A. & Cairns, N.J. A morphometric study of the spatial patterns of TDP-43 immunoreactive neuronal inclusions in frontotemporal lobar degeneration (FTLD) with progranulin (GRN) mutation. Histology and Histopathology 2011; 26: 185-190. PMC3017380

Name: Lisa Taylor-Reinwald
Year: 2011

Reference:

Armstrong, R.A., Gearing, M., Bigio, E.H., Cruz-Sanchez, F.F., Duyckaerts, C., Mackenzie, I.R., Perry, R.H., Skullerud, K., Yokoo, H., & Cairns, N.J. The spectrum and severity of FUS-immunoreactive inclusions in the frontal and temporal lobes of ten cases of neuronal intermediate filament inclusion disease. Acta Neuropathologica 2011; 121: 219-128. PMC3035044

Name: Lisa Taylor-Reinwald
Year: 2011

Reference:

Armstrong, R.A., Gearing, M., Bigio, E.H., Cruz-Sanchez, F.F., Duyckaerts, C., Mackenzie, I.R., Perry, R.H., Skullerud, K., Yokoo, H., Cairns, N.J. (2011) Spatial patterns of FUS-immunoreactive neuronal cytoplasmic inclusions (NCI) in neuronal intermediate filament inclusion disease (NIFID). Journal of Neural Transmission 2011; 118: 1651-1657. PMC3199334

Name: Randall Bateman
Year: 2011

Reference:

Bateman RJ, Aisen PS, De Strooper B, Fox NC, Lemere CA, Ringman JM, Salloway S, Sperling RA, Windisch M, Xiong C. Autosomal-dominant Alzheimer’s disease: a review and proposal for the prevention of Alzheimer’s disease. Alzheimers Res Ther. 2011 Jan 6;2(6):35. PMCID: PMC3109410.

Name: Brian Carpenter
Year: 2011

Reference:

Carpenter BD, Zoller SM, Balsis S, Otilingam PG, Gatz M. Demographic and contextual factors related to knowledge about Alzheimer’s disease. American Journal of Alzheimer’s Disease 2011; 26: 121-126. DOI: 10.1177/1533317510394157

Name: David Carr
Year: 2011

Reference:

Carr DB, Barco P, Wallendorf MJ, Snellgrove CA, Ott BR. Predicting Road Test Performance in Drivers with Dementia. JAGS 2011; 59:2112-2117. (PMCID: PMC3228409)

Name: David Balota
Year: 2011

Reference:

Castel AD, Humphreys KL, Lee SS, GalvÃƒÆ’Ã‚Â¡n A, Balota DA, McCabe DP. The development of memory efficiency and value-directed remembering across the life span: A cross-sectional study of memory and selectivity. Developmental Psychology 2011; 47(6): 1553-1564. PMCID: PMC3312745.

Name: alison goate
Year: 2011

Reference:

Castellano JM, Kim J, Stewart FR, Jiang H, Demattos RB, Patterson BW, Fagan AM, Morris JC, Mawuenyega KG, Cruchaga C, Goate AM, Bales KR, Paul SM, Bateman RJ, Holtzman DM.
Human apoE Isoforms Differentially Regulate Brain Amyloid-{beta} Peptide Clearance. Sci Transl Med. 2011, 29;3(89):89ra57. PMCID: 329176

Name: Randall Bateman
Year: 2011

Reference:

Castellano JM, Kim J, Stewart FR, Jiang H, Demattos RB, Patterson BW, Fagan AM, Morris JC, Mawuenyega KG, Cruchaga C, Goate AM, Bales KR, Paul SM, Bateman RJ, Holtzman DM. Human apoE Isoforms Differentially Regulate Brain Amyloid-{beta} Peptide Clearance. Sci Transl Med. 2011 Jun 29;3(89):89ra57. PMC Journal – In Process. PMID#21715678

Name: alison goate
Year: 2011

Reference:

Chen-Plotkin AS, Martinez-Lage M, Sleiman PM, Hu W, Greene R, Wood EM, Bing S, Grossman M, Schellenberg GD, Hatanpaa KJ, Weiner MF, White CL 3rd, Brooks WS, Halliday GM, Kril JJ, Gearing M, Beach TG, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Pickering-Brown SM, Snowden J, van Swieten JC, Heutink P, Seelaar H, Murrell JR, Ghetti B, Spina S, Grafman J, Kaye JA, Woltjer RL, Mesulam M, Bigio E, LladÃ³ A, Miller BL, Alzualde A, Moreno F, Rohrer JD, Mackenzie IR, Feldman HH, Hamilton RL, Cruts M, Engelborghs S, De Deyn PP, Van Broeckhoven C, Bird TD, Cairns NJ, Goate A, Frosch MP, Riederer PF, Bogdanovic N, Lee VM, Trojanowski JQ, Van Deerlin VM. Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration. Arch Neurol. 2011, 68(4):488-97

Name: Lisa Taylor-Reinwald
Year: 2011

Reference:

Chen-Plotkin, A.S., Martinez-Lage, M., Sleiman, P.M., Hu, W., Greene, R., Wood, E.M., Bing, S., Grossman, M., Schellenberg, G.D., Hatanpaa, K.J., Weiner, M.F., White, C.L. 3rd, Brooks, W.S., Halliday, G.M., Kril, J.J., Gearing, M., Beach, T.G., Graff-Radford, N.R., Dickson, D.W., Rademakers, R., Boeve, B.F., Pickering-Brown, S.M., Snowden, J., van Swieten, J.C., Heutink, P., Seelaar, H., Murrell, J.R., Ghetti, B., Spina, S., Grafman, J., Kaye, J.A., Woltjer, R.L., Mesulam, M., Bigio, E., LladÃ³, A., Miller, B.L., Alzualde, A., Moreno, F., Rohrer, J.D., Mackenzie, I.R., Feldman, H.H., Hamilton, R.L., Cruts, M., Engelborghs, S., De Deyn, P.P., Van Broeckhoven, C., Bird, T.D., Cairns, N.J., Goate, A., Frosch, M.P., Riederer, P.F., Bogdanovic, N., Lee, V.M., Trojanowski, J.Q., & Van Deerlin, V.M. Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration. Archives of Neurology 2011; 68: 488-497. PMC3160280

Name: Yvette Sheline
Year: 2011

Reference:

Cirrito JR, Disabato BM, Restivo JL, Verges DK, Goebel WD, Sathyan A, Hayreh D, D’Angelo G, Benzinger T, Yoon H, Kim J, Morris JC, Mintun MA, Sheline YI. Serotonin signaling is associated with lower amyloid B{beta} levels and plaques in transgenic mice and humans. Proc Natl Acad Sci USA 108: 14968-73 (2011). PMID: PMC3169155.

Name: Brianne Disabato
Year: 2011

Reference:

Cirrito JR, Disabato BM, Restivo JL, Verges DK, Goebel WD, Sathyan A, Hayreh D, D’Angelo G, Benzinger T, Yoon H, Kim J, Morris JC, Mintun MA, Sheline YI. Serotonin signaling is associated with lower amyloid-Î² levels and plaques in transgenic mice and humans. Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14968-73. PMID: 21873225

Name: Anne Fagan
Year: 2011

Reference:

Craig-Schapiro R, Kuhn M, Xiong C, Pickering EH, Liu J, Misko TP, Perrin RJ, Bales KR, Soares H, Fagan AM, Holtzman DM. Multiplexed immunoaasay panel identifies novel CSF biomarkers for Alzheimer’s disease diagnosis and prognosis. PLoS One. 2011 Apr 19;6(4):e18850. PMCID: PMC3079734

Name: Carlos Cruchaga
Year: 2011

Reference:

Cruchaga C, Graff C, Chiang HH, Wang J, Hinrichs AL, Spiegel N, Bertelsen S, Mayo K, Norton JB, Morris JC, Goate A. Association of TMEM106B Gene Polymorphism With Age at Onset in Granulin Mutation Carriers and Plasma Granulin Protein Levels. Arch Neurol. 2011 Submitted Jan 10

Name: alison goate
Year: 2011

Reference:

Name: Anne Fagan
Year: 2011

Reference:

Cruchaga C, Nowotny P, Kauwe JS, Ridge PG, Mayo K, Bertelsen S, Hinrichs A, Fagan AM, Holtzman DM, Morris JC, Goate AM; Alzheimer’s Disease Neuroimaging Initiative.
association and expression analyses with single-nucleotide polymorphisms in TOMM40 in Alzheimer Disease. Archives of Neurology 2011, 68:1013-1019. PMID: 21825236

Name: Petra Nowotny
Year: 2011

Reference:

Cruchaga C, Nowotny P, Kauwe JSK, Mayo K, Bertelsen S, Hinrichs A, the Alzheimer’s Disease Neuroimaging Initiative, Fagan A, Holtzman D, Morris J and Goate A. Association and Expression analyses with SNPs in TOMM40 in Alzheimer’s Disease Submitted to Archives of Neurology

Name: Anne Fagan
Year: 2011

Reference:

Fagan AM, Shaw LM, Xiong C, Vanderstichele H, Mintun MA, Trojanowski JQ, Coart E, Morris JC, Holtzman DM. Comparison of analytical platforms for cerebrospinal fluid measures of ABeta-42, total tau and p-tau181 for identifying Alzheimer’s disease amyloid plaque pathology. Archives of Neurology, 2011, 68:1137-44. PMCID: PMC3154969

Name: Anne Fagan
Year: 2011

Reference:

Fagan AM. Cerebrospinal fluid biomarkers of â€œpreclinicalâ€ and early stage Alzheimerâ€™s disease, International Drug Discovery, 2011, in press.

Name: Yvette Sheline
Year: 2011

Reference:

Galvin JE, Price JL, Yan L, Morris JC, Sheline YI. Resting Bold fMRi Differentiates Dementia with Lewy Bodies vs. Alzheimer Disease. Neurology 24:1797-803 (2011). PMCID: PMC 310012.

Name: Lisa Taylor-Reinwald
Year: 2011

Reference:

Ghoshal, N., Dearborn, J.T., Wozniak, D.F., & Cairns, N.J. (2011) Core features of frontotemporal dementia recapitulated in progranulin knockout mice. Neurobiology of Disease 2011; 45: 395-408. PMC3225509

Name: Denise Head
Year: 2011

Reference:

Gordon, B. A., Shelton, J. T., Bugg, J. M., McDaniel, M. A., Head, D. (2011). Structural
correlates of prospective memory. Neuropsychologia, 49, 3795-3800. PMID:21982698

Name: Gregory Zipfel
Year: 2011

Reference:

Han BH, Zhou M, Vellimana AK, Milner E, Kim DH, Greenberg JK, Chu W, Mach RH, Zipfel GJ. Resorufin Analogs Preferentially Bind Cerebrovascular Amyloid: Potential Use as Imaging Ligands for Cerebral Amyloid Angiopathy, Molecular Neurodegeneration, 6(1):86, 2011. PMID: 22192811.

Name: alison goate
Year: 2011

Reference:

Hata S, Fujishige S, Araki Y, Taniguchi M, Urakami K, Peskind E, Akatsu H, Araseki M, Yamamoto K, Martins RN, Maeda M, Nishimura M, Levey A, Chung KA, Montine T, Leverenz J, Fagan A, Goate A, Bateman R, Holtzman DM, Yamamoto T, Nakaya T, Gandy S, Suzuki T. Alternative processing of Î³-secretase substrates in common forms of mild cognitive impairment and alzheimer’s disease: Evidence for Î³-secretase dysfunction. Ann Neurol. 2011, 69(6):1026-31.

Name: Anne Fagan
Year: 2011

Reference:

Hata S, Fujishige S, Araki Y, Taniguchi M, Urakami K, Peskind E, Akatsu H, Araseki M, Yamamoto K, Martins RN, Maeda M, Nishimura M, Levey A, Chung KA, Montine T, Leverenz J, Fagan A, Goate A, Bateman R, Holtzman DM, Yamamoto T, Nakaya T, Gandy S, Suzuki T. Alternative processing of y-secretase substrates in common forms of Mild Cognitive Impairment and Alzheimer’s disease: Evidence for y-secretase dysfunction. Annals of Neurology, 2011 Jun;69(6):1026-31. PMCID: PMC3306841

Name: Denise Head
Year: 2011

Reference:

Head D, Singh T, Bugg JM. The moderating role of exercise on stress-related effects
on the hippocampus and memory in later adulthood. Submitted. Journals of Gerontology: Biological Sciences

Name: Carlos Cruchaga
Year: 2011

Reference:

Hollingworth P, Harold D, Sims R, Gerrish A, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, Ivanov D, Widdowson C, Chapman J, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Beaumont H, Warden D, Wilcock G, Love S, Kehoe PG, Hooper NN, Vardy ERLC, Hardy J, Mead S, Fox NC, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, Rüther E, Heun R, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Gallacher J, Rujescu D, Giegling I, Goate AM, Kauwe JSK, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Pankratz VS, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Dickson DW, Graff-Radford NR, Petersen RC, the Alzheimer’s Disease Neuroimaging Initiative, Ikram MA, DeStefano AL, Fitzpatrick AL, Lopez O, Launer LJ, Seshadri S, CHARGE consortium, Berr C, Campion D, Epelbaum J, Dartigues JF, Tzourio C, Alpérovitch A, Lathrop M, EADI1 consortium, van Duijn CM, Breteler MMB, Feulner T, Riehle FP, Krawczak M, Schreiber S, Mayhaus M, Nicolhaus S, Wagenpfeil S, Steinberg S, Stefansson H, Stefansson K, Snædal J, Björnsson S, Jonsson PV, Chouraki V, Genier-Boley B, Hiltunen M, Combarros O, Zelenika D, Delepine M, Bullido MJ, Pasquier F, Mateo I, Franck-Garcia A, Porcellini E, Hanon O, Coto E, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Bossù P, Piccardi P, Arosio B, Annoni G, Seripa D, Scarpini E, Galimberti D, Brice A, Hannequin D, Licastro F, Soinine H, Jones L, Holmans PA, Jonsson T, Riemenschneider M, Morgan K, Younkin SG, O’Donovan M, Owen MJ, Lambert CH, Amouyel P, and Williams J. Evidence for novel susceptibility loci in Alzheimer’s disease. Nature Genetics. In press

Name: alison goate
Year: 2011

Reference:

Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, Ivanov D, Widdowson C, Chapman J, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Beaumont H, Warden D, Wilcock G, Love S, Kehoe PG, Hooper NM, Vardy ER, Hardy J, Mead S, Fox NC, Rossor M, Collinge J, Maier W, Jessen F, RÃ¼ther E, SchÃ¼rmann B, Heun R, KÃ¶lsch H, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, FrÃ¶lich L, Hampel H, Gallacher J, HÃ¼ll M, Rujescu D, Giegling I, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, MÃ¼hleisen TW, NÃ¶then MM, Moebus S, JÃ¶ckel KH, Klopp N, Wichmann HE, Pankratz VS, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Dickson DW, Graff-Radford NR, Petersen RC; Alzheimer’s Disease Neuroimaging Initiative, van Duijn CM, Breteler MM, Ikram MA, DeStefano AL, Fitzpatrick AL, Lopez O, Launer LJ, Seshadri S; CHARGE consortium, Berr C, Campion D, Epelbaum J, Dartigues JF, Tzourio C, AlpÃ©rovitch A, Lathrop M; EADI1 consortium, Feulner TM, Friedrich P, Riehle C, Krawczak M, Schreiber S, Mayhaus M, Nicolhaus S, Wagenpfeil S, Steinberg S, Stefansson H, Stefansson K, Snaedal J, BjÃ¶rnsson S, Jonsson PV, Chouraki V, Genier-Boley B, Hiltunen M, Soininen H, Combarros O, Zelenika D, Delepine M, Bullido MJ, Pasquier F, Mateo I, Frank-Garcia A, Porcellini E, Hanon O, Coto E, Alvarez V, Bosco P, Siciliano G, Mancuso M, Panza F, Solfrizzi V, Nacmias B, Sorbi S, BossÃ¹ P, Piccardi P, Arosio B, Annoni G, Seripa D, Pilotto A, Scarpini E, Galimberti D, Brice A, Hannequin D, Licastro F, Jones L, Holmans PA, Jonsson T, Riemenschneider M, Morgan K, Younkin SG, Owen MJ, O’Donovan M, Amouyel P, Williams J. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer’s disease. Nat Genet. 2011, 43(5):429-35. PMCID: 3084173

Name: alison goate
Year: 2011

Reference:

Holtzman DM, Goate A, Kelly J, Sperling R. Mapping the road forward in Alzheimer’s disease.
Sci Transl Med. 2011; 3(114):114ps48.

Name: David Balota
Year: 2011

Reference:

Jackson J, Balota DA, Head D. Exploring the relationship between personality and regional brain volume in healthy aging. Neurobiology Of Aging 2011; 32, 12: 2162-2171. PMCID: PMC2891197.

Name: Anne Fagan
Year: 2011

Reference:

Kauwe JS, Cruchaga C, Karch CM, Sadler B, Lee M, Mayo K, Latu W, Su’a M, Fagan AM, Holtzman DM, Morris JC, Alzheimer’s Disease Neuroimaging Initiative, Goate AM. Fine mapping of genetic variants in BIN1CLU.CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer’s Disease. PLoS One. 2011 Feb 9;6(2):e15918. PMCID: PMC3036586

Name: alison goate
Year: 2011

Reference:

Kauwe JS, Cruchaga C, Karch CM, Sadler B, Lee M, Mayo K, Latu W, Su’a M, Fagan AM, Holtzman DM, Morris JC; Alzheimer’s Disease Neuroimaging Initiative, Goate AM. Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer’s disease PLoS One. 2011,6(2):e15918. PMCID 3036586

Name: Anne Fagan
Year: 2011

Reference:

Mattsson N, Andreasson U, Persson S, Arai H, Batish SD, Bernardini S, Bocchio-Chiavetto L, Blankenstein MA, Carrillo MC, Chalbot S, Coart E, Chiasserini D, Cutler N, Dahlfors G, Duller S, Fagan AM, Forlenza O, Frisoni GB, Galasko D, Galimberti D, Hampel H, Handberg A, Heneka MT, Herskovits AZ, Herukka SK, Holtzman DM, Humpel C, Hyman BT, Iqbal K, Jucker M, Kaeser SA, Kaiser E, Kapaki E, Kidd D, Klivenyi P, Knudsen CS, Kummer MP, Lui J, LladÃƒÂ³ A, Lewczuk P, Li QX, Martins R, Masters C, McAuliffe J, Mercken M, Moghekar A, Molinuevo JL, Montine TJ, Nowatzke W, O’Brien R, Otto M, Paraskevas GP, Parnetti L, Petersen RC, Prvulovic D, de Reus HP, Rissman RA, Scarpini E, Stefani A, Soininen H, Schroder J, Shaw LM, Skinningsrud A, Skrogstad B, Spreer A, Talib L, Teunissen C, Trojanowski JQ, Tumani H, Umek RM, Van Broeck B, Vanderstichele H, Vecsei L, Verbeek MM, Windisch M, Zhang J, Zetterberg H, Blennow K. The AlzheimerÃ¢â‚¬â„¢s Association External Quality Control Program for Cerebrospinal Fluid Biomarkers. Alzheimer’s Dementia, 2011,7(4):386-39. PMCID: PMC3710290

Name: Carlos Cruchaga
Year: 2011

Reference:

Naj AC, Jun G, Beecham GW, Wang L, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JSK, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FJ, Baldwin CT, Green RC, Rogaeva E, George-Hyslop PS, Alzheimer Disease Genetics Consortium#, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TH, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, and Schellenberg GR. Genome-wide Association Study of Late-Onset Alzheimer Disease identifies disease associated variants in MS4A4/MS4A6E, CD2AP, CD33, and EPHA1. Nature Genetics. In press

Name: alison goate
Year: 2011

Reference:

Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, St George-Hyslop P, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, DeCarli C, DeKosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer’s disease. Nat Genet. 2011, 43(5):436-41. PMCID: 3090745

Name: Lisa Taylor-Reinwald
Year: 2011

Reference:

Naj, A.C., Jun, G., Beecham, G.W., Wang, L.S., Vardarajan, B.N., Buros, J., Gallins, P.J., Buxbaum, J.D., Jarvik, G.P., Crane, P.K., Larson, E.B., Bird, T.D., Boeve, B.F., Graff-Radford, N.R., De Jager, P.L., Evans, D., Schneider, J.A., Carrasquillo, M.M., Ertekin-Taner, N., Younkin, S.G., Cruchaga, C., Kauwe, J.S., Nowotny, P., Kramer, P., Hardy, J., Huentelman, M.J., Myers, A.J., Barmada, M.M., Demirci, F.Y., Baldwin, C.T., Green, R.C., Rogaeva, E., George-Hyslop, P.S., Arnold, S.E., Barber, R., Beach, T., Bigio, E.H., Bowen, J.D., Boxer, A., Burke, J.R., Cairns, N.J., Carlson, C.S., Carney, R.M., Carroll, S.L., Chui, H.C., Clark, D.G., Corneveaux, J., Cotman, C.W., Cummings, J.L., Decarli, C., Dekosky, S.T., Diaz-Arrastia, R., Dick. M., Dickson, D.W., Ellis, W.G., Faber, K.M., Fallon, K.B., Farlow, M.R., Ferris, S., Frosch, M.P., Galasko, D.R., Ganguli, M., Gearing, M., Geschwind, D.H., Ghetti, B., Gilbert, J.R., Gilman, S., Giordani, B., Glass, J.D., Growdon, J.H., Hamilton, R.L., Harrell, L.E., Head, E., Honig, L.S., Hulette, C.M., Hyman, B.T., Jicha, G.A., Jin, L.W., Johnson, N., Karlawish, J., Karydas, A., Kaye, J.A., Kim, R., Koo, E.H., Kowall, N.W., Lah, J.J., Levey, A.I., Lieberman, A.P., Lopez, O.L., Mack, W.J., Marson, D.C., Martiniuk, F., Mash, D.C., Masliah, E., McCormick, W.C., McCurry, S.M., McDavid, A.N., McKee, A.C., Mesulam, M., Miller, B.L., Miller, C.A., Miller, J.W., Parisi, J.E., Perl, D.P., Peskind, E., Petersen, R.C., Poon, W.W., Quinn, J.F., Rajbhandary, R.A., Raskind, M., Reisberg, B., Ringman, J.M., Roberson, E.D., Rosenberg, R.N., Sano, M., Schneider, L.S., Seeley, W., Shelanski, M.L., Slifer, M.A., Smith, C.D., Sonnen, J.A., Spina, S., Stern, R.A., Tanzi, R.E., Trojanowski, J.Q., Troncoso, J.C., Van Deerlin, V.M., Vinters, H.V., Vonsattel, J.P., Weintraub, S., Welsh-Bohmer, K.A., Williamson, J., Woltjer, R.L., Cantwell, L.B., Dombroski, B.A., Beekly, D., Lunetta, K.L., Martin, E.R., Kamboh, M.I., Saykin, A.J., Reiman, E.M., Bennett, D.A., Morris, J.C., Montine, T.J., Goate, A.M., Blacker, D., Tsuang, D.W., Hakonarson, H., Kukull, W.A., Foroud, T.M., Haines, J.L., Mayeux, R., Pericak-Vance, M.A., Farrer, L.A., & Schellenberg, G.D. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer’s disease. Nature Genetics 2011; 43: 436-441. PMC3090745

Name: alison goate
Year: 2011

Reference:

Page T, Gitcho MA, Mosaheb S, Carter D, Chakraverty S, Perry RH, Bigio EH, Gearing M, Ferrer I, Goate AM, Cairns NJ, Thorpe JR. FUS Immunogold Labeling TEM Analysis of the Neuronal Cytoplasmic Inclusions of Neuronal Intermediate Filament Inclusion Disease: A Frontotemporal Lobar Degeneration with FUS Proteinopathy. J Mol Neurosci. 2011; 45(3): 409-21.

Name: Anne Fagan
Year: 2011

Reference:

Perrin R, Craig-Schapiro R, Malone J, Shah A, Gilmore P, Davis A, Roe C, Peskind E, Li G, Galasko D, Clark C, Quinn J, Kaye J, Morris J, Holtzman D, Townsend R, Fagan AM. Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer’s disease. PLoS One, 2011; 6:e16032. PMID: 21264269

Name: Catherine Roe
Year: 2011

Reference:

Perrin RJ, Craig-Shapiro R, Malone JP, Shah AR, Gilmore P, Davis AE, Roe CM, Peskind ER, Li G, Galasko DR, Clark CM, Quinn JF, Kaye JA, Morris JC, Holtzman DM, Townsend RR, Fagan AM. Identification and validation of novel cerebrospinal fluid biomarkers of staging early Alzheimerâ€™s disease. PLoS ONE 2011; 6:e16032 PMCID: PMC3020224

Name: alison goate
Year: 2011

Reference:

Ringman JM, Gylys KH, Medina LD, Fox M, Kepe V, Flores DL, Apostolova LG, Barrio JR, Small G, Silverman DH, Siu E, Cederbaum S, Hecimovic S, Malnar M, Chakraverty S, Goate AM, Bird TD, Leverenz JB. Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer’s disease due to a novel PSEN1 mutation. Neurosci Lett. 2011; 487(3):287-92. PMCID: PMC3034479

Name: Alison Goate
Year: 2011

Reference:

Name: Catherine Roe
Year: 2011

Reference:

Roe CM, Fagan AM, Grant EA, Marcus DS, Benzinger TLS, Mintun MA, Holtzman DM, Morris JC. Cerebrospinal fluid biomarkers, education, brain volume, and future cognition. Archives of Neurology 2011;68:1145-1152. PMCID: PMC3203689.

Name: Anne Fagan
Year: 2011

Reference:

Name: Anne Fagan
Year: 2011

Reference:

Roe CM, Fagan AM, Williams MM, Ghoshal N, Aeschleman M, Grant EA, Marcus DS, Mintun MA, Holtzman DM, Morris JC. Improving CSF biomarker accuracy in predicting prevalent and incident Alzheimer disease. Neurology, 2011, 76:501-10. PMCID: PMC3154969

Name: Catherine Roe
Year: 2011

Reference:

Roe CM, Fagan AM, Williams MM, Ghoshal N, Aeschleman M, Grant EA, Marcus DS, Mintun MA, Holtzman DM, Morris JC. Improving CSF Biomarker Accuracy in Predicting Prevalent and Incident Alzheimerâ€™s Disease. Neurology 2011;76(6):501-510. PMCID: PMC3053181.

Name: Anne Fagan
Year: 2011

Reference:

Sperling RA, Aisen PS, Beckett LA, Bennett DA, Craft S, Fagan AM, Iwatsubo T, Jack CR Jr, Kaye J, Montine TJ, Park DC, Reiman EM, Rowe CC, Siemers E, Stern Y, Yaffe K, Carrillo MC, Thies B, Morrison-Bogorad M, Wagster MV, Phelps CH. Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. AlzheimerÃ¢â‚¬â„¢s Dementia, 2011, 7:280-92. PMCID: PMC3220946

Name: Anne Fagan
Year: 2011

Reference:

Tarawneh R, D’Angelo, G, Macy E, Xiong C, Carter D, Cairns NJ, Fagan AM, PhD, Head D, Mintun MA, Ladenson JH, Lee J-M, Morris JC, Holtzman DM. Visinin-like protein-1: Diagnostic and prognostic biomarker in Alzheimer disease. Annals of Neurology, 2011, 70:274-85. PMCID: PMC3154071

Name: Lisa Taylor-Reinwald
Year: 2011

Reference:

Tarawneh, R., D’Angelo, G., Macy, E., Xiong, C., Carter, D., Cairns, N.J., Fagan, A.M., Head, D., Mintun, M.A., Ladenson, J.H., Lee, J.M., Morris, J.C., & Holtzman, D.M. Visinin-like protein-1: diagnostic and prognostic biomarker in Alzheimer disease. Annals of Neurology 2011; 70: 274-285. PMC3154071

Name: Anne Fagan
Year: 2011

Reference:

Wang L, Fagan AM, Shah AR, Beg MF, Csernansky JG, Morris JC, Holtzman DM. Cerebrospinal fluid proteins predict longitudinal hippocampal degeneration in early-stage dementia of the Alzheimer type. Alzheimer Disease and Associated Disorders, 2011 Dec 7. PMCID: PMC3309103

Name: Lisa Taylor-Reinwald
Year: 2011

Reference:

Weiner, M.W., Veitch, D.P., Aisen, P.S., Beckett, L.A., Cairns, N.J., Green, R.C., Harvey, D., Jack, C.R., Jagust, W., Liu, E., Morris, J.C., Petersen, R.C., Saykin, A.J., Schmidt, M.E., Shaw, L., Siuciak, J.A., Soares, H., Toga, A.W., Trojanowski, J.Q. & the Alzheimer’s Disease Neuroimaging Initiative: A review of papers published since its inception. Alzheimerâ€™s and Dementia 2011 (in press).

Name: alison goate
Year: 2011

Reference:

Wijsman EM, Pankratz ND, Choi Y, Rothstein JH, Faber KM, Cheng R, Lee JH, Bird TD, Bennett DA, Diaz-Arrastia R, Goate AM, Farlow M, Ghetti B, Sweet RA, Foroud TM, Mayeux R; NIA-LOAD/NCRAD Family Study Group. Genome-wide association of familial late-onset Alzheimer’s disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE. PLoS Genet. 2011, 7(2):e1001308. PMCID: 3040659

Name: Anne Fagan
Year: 2011

Reference:

Xiong C, Roe CM, Buckles V, Fagan A, Holtzman D, Balota D, Duchek J, Storandt M, Mintun M, Grant E, Snyder AZ, Head D, Benzinger TL, Mettenburg J, Csernansky J, Morris JC. Role of family history for Alzheimer biomarker abnormalities in the Adult Children Study. Archives of Neurology 2011 Oct;68(10):1313-9. PMCID: PMC3327304

Name: David Balota
Year: 2011

Reference:

Xiong C, Roe CM, Buckles V, Fagan A, Holtzman D, Balota D, Morris JC. Role of family history for Alzheimer biomarker abnormalities in the Adult Children Study. Archives Of Neurology 2011; 68(10): 1313-1319. PMCID: PMC3327304.

Name: Lisa Taylor-Reinwald
Year: 2011

Reference:

Zhu, L., Cairns, N.J., Tabbal, S.D., & Racette, B.A. Pregnancy in multiple system atrophy: a case report. Journal of Medical Case Reports 2011; 5: 599. PMC3261365

Name: David Carr
Year: 2010

Reference:

45. Carr David B, Ott Brian R. The Older Driver with Cognitive Impairment â€œItâ€™s A Very Frustrating Lifeâ€. JAMA 2010 Apr 28;303(16):1632-41. (PMCID: PMC2915446)

Name: Anne Fagan
Year: 2010

Reference:

Ances BM, Christensen JJ, Teshome M, Taylor J, Xiong C, Aldea P, Fagan AM, Holtzman DM, Morris JC, Mintun MA, Clifford DB. Cognitively unimpaired HIV+ participants do not have increased 11C-PiB: A case control study. Neurology, 2010; 75:111-115. PMCID: PMC2905926

Name: Randall Bateman
Year: 2010

Reference:

Cook JJ, Wildsmith KR, Gilberto DB, Holahan MA, Kinney GG, Mathers PD, Michener MS, Price EA, Shearman MS, Simon AJ, Wang JX, Wu G, Yarasheski KE, Bateman RJ. Acute Gamma-Secretase Inhibition of Nonhuman Primate CNS Shifts Amyloid Precursor Protein (APP) Metabolism from Amyloid- Production to Alternative APP Fragments without Amyloid-Beta Rebound. J Neurosci. 2010 May 12;30(19):6743-50. PMID: 20463236

Name: Anne Fagan
Year: 2010

Reference:

Craig-Schapiro R, Perrin RJ, Roe CM, Xiong C, Carter D, Cairns NJ, Mintun MA, Peskind ER, Li G, Galasko DR, Clark CM, Quinn JF, Dâ€™Angelo G, Malone JP, Townsend RR, Morris JC, Fagan AM, Holtzman DM. YKL-40: A novel prognostic fluid biomarker for preclinical Alzheimerâ€™s disease. Biological Psychiatry, 2010; 68:903-12. PMCID: PMC3011944

Name: Alison Goate
Year: 2010

Reference:

Cruchaga C, Kauwe JS, Mayo K, Bertelsen S, Nowotny P, Shah AR, Abraham R, Hollingworth P, Harold D, Owen MJ, Williams J, Lovestone S, Peskind E, the Alzheimer’s Disease Neuroimaging Initiative, Morris JC, Fagan AM, Holtzman DM, and Goate A. SNPs Associated with Cerebrospinal Fluid Phospho-Tau Levels Influence Rate of Decline in Alzheimer’s Disease. 2010; 6(9). PMCID: 2940763

Name: Anne Fagan
Year: 2010

Reference:

Cruchaga C, Kauwe JS, Mayo K, Spiegel N, Bertelsen S, Nowotny P, Shah AR, Abraham R, Hollingworth P, Harold D, Owen MM, Williams J, Lovestone S, Peskind ER, Li G, Leverenz JB, Galasko D; Alzheimer’s Disease Neuroimaging Initiative, Morris JC, Fagan AM, Holtzman DM, Goate AM. SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer’s disease. PLoS Genetics, 2010; Sep 16;6(9). PMCID: PMC2940763

Name: Anne Fagan
Year: 2010

Reference:

Fagan AM and Holtzman DM. CSF biomarkers of Alzheimer’s disease. Biomarkers in Medicine, 2010; 4:51-63. PMCID: PMC2846664

Name: Anne Fagan
Year: 2010

Reference:

Galvin JE, Fagan AM, Holtzman DM, Mintun MA, Morris JC. Relationship of dementia screening tests with biomarkers of Alzheimerâ€™s disease. Brain 2010; 133:3290-3300. PMCID: PMC2965421

Name: Alison Goate
Year: 2010

Reference:

Gao X, Joselin AP, Wang L, Kar A, Ray P, Bateman A, Goate AM, Wu JY. Progranulin promotes neurite outgrowth and neuronal differentiation by regulating GSK-3β. Protein Cell. 2010; 1(6):552-62.

Name: Alison Goate
Year: 2010

Reference:

Goate A, Holtzman DM. Biomarkers will revolutionize the way we diagnose and treat Alzheimer’s disease. Biomark Med. 2010; 4(1):1-2.

Name: Randall Bateman
Year: 2010

Reference:

Hata S, Fujishige S, Araki Y, Taniguchi M, Urakami K, Peskind E, Akatsu H, Araseki M, Yamamoto K, Martins RN, Maeda M, Nishimura M, Levey A, Chung KA, Montine T, Leverenz J, Fagan A, Goate A, Bateman R, Holtzman DM, Yamamoto T, Nakaya T, Gandy S, Suzuki T. Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer’s disease: Evidence for γ-secretase dysfunction. Annals of Neurology 2010;doi: 10.1002/ana.22343.

Name: David Balota
Year: 2010

Reference:

Hutchison KA, Balota DA, Duchek JM. The utility of Stroop task switching as a marker for early-stage Alzheimer’s disease. Psychology & Aging 2010; 25: 545-59. PMCID: 2946107.

Name: Alison Goate
Year: 2010

Reference:

Jones L, Holmans PA, Hamshere ML, Harold D, Moskvina V, Ivanov D, Pocklington A, Abraham R, Hollingworth P, Sims R, Gerrish A, Pahwa JS, Jones N, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, van den Bussche H, Heuser I, Peters O, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Rüther E, Carrasquillo MM, Pankratz VS, Younkin SG, Hardy J, O’Donovan MC, Owen MJ, Williams J. Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer’s disease. PLoS One. 2010; 5 (11):e13950. PMCID: PMC2981526

Name: Alison Goate
Year: 2010

Reference:

Jun G, Naj AC, Beecham GW, Wang LS, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, Fallin MD, Friedland R, Inzelberg R, Kramer P, Rogaeva E, St George-Hyslop P; Alzheimer’s Disease Genetics Consortium, Cantwell LB, Dombroski BA, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Lunetta KL, Martin ER, Montine TJ, Goate AM, Blacker D, Tsuang DW, Beekly D, Cupples LA, Hakonarson H, Kukull W, Foroud TM, Haines J, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD. Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol. 2010;67(12):1473-84.

Name: Keoni Kauwe
Year: 2010

Reference:

Kauwe JS, Cruchaga C, Bertelsen S, Mayo K, Latu W, Nowotny P, Hinrichs AL, Fagan AM, Holtzman DM; Alzheimer’s Disease Neuroimaging Initiative, Goate AM. Validating predicted biological effects of Alzheimer’s disease associated SNPs using CSF biomarker levels. J Alzheimers Dis. 2010;21(3):833-42

Name: Anne Fagan
Year: 2010

Reference:

Kauwe JSK, Cruchaga C, Bertelsen S, Mayo K, Latu W, Nowotny P, Hinrichs AL, Fagan AM, Holtzman DM, ADNI and Goate AM. Validating predicted biological effects of Alzheimerâ€™s disease associated SNPs using CSF biomarker levels. Journal of Alzheimer Disease, 2010; 21:833-42 PMCID: PMC3032214

Name: Alison Goate
Year: 2010

Reference:

Kauwe JSK, Cruchaga C, Bertelsen S, Mayo K, Latu, W, Nowotny P, Hinrichs AL, Fagan AM, Holtzman DM, ADNI, Goate AM. Validating predicted biological effects of Alzheimer’s disease associated SNPs using CSF biomarker levels. Journal of Alzheimer’s Disease. 2010; 21(3): 833-42. PMCID: 3032214

Name: Anne Fagan
Year: 2010

Reference:

Liang K, Mintun M, Fagan A, Goate A, Bugg J, Holtzman D, Morris JC, Head D. Exercise and Alzheimerâ€™s disease biomarkers in cognitively normal older adults. Annals of Neurology, 2010; 68:311-18. PMCID: PMC2936720

Name: Alison Goate
Year: 2010

Reference:

Liang KY, Mintun MA, Fagan AM, Goate AM, Bugg JM, Holtzman DM, Morris JC, Head D. Exercise and Alzheimer’s disease biomarkers in cognitively normal older adults. Ann Neurol. 2010; 68(3):311-8. PMCID: 2936720

Name: Alison Goate
Year: 2010

Reference:

Malnar M, Kosicek M, Mitterreiter S, Omerbasic D, Lichtenthaler SF, Goate A, Hecimovic S. Niemann-Pick type C cells show cholesterol dependent decrease of APP expression at the cell surface and its increased processing through the beta-secretase pathway. Biochim Biophys Acta. 2010; 1802(7-8): 682-91. PMCID: 2903680

Name: Randall Bateman
Year: 2010

Reference:

Mawuenyega KG, Sigurdson W, Ovod V, Munsell L, Kasten T, Morris JC, Yarasheski KE, Bateman RJ. Decreased Clearance of CNS Amyloid-β in Alzheimer’s Disease. Science December 2010: 330 (6012): 1774.

Name: David Carr
Year: 2010

Reference:

Meuser TM, Carr DB, Irmiter C, Schwartzberg JG, Ulfarsson GF. The American Medical Association Older Driver Curriculum for Health Professionals: Changes in Trainee Confidence, Attitudes & Practice Behavior. Gerontology & Geriatrics Education 2010;31:1-21 (PMCID: PMC3074473)

Name: Anne Fagan
Year: 2010

Reference:

Morris JC, Roe CM, Xiong C, Fagan AM, Goate AM, Holtzman DM, Mintun MA. APOE predicts AÎ² but not tau Alzheimerâ€™s pathology in cognitively normal aging, Annals of Neurology, 2010; 67:122-31. PMCID: PMC2830375

Name: Sidney Strickland
Year: 2010

Reference:

Neuron. 2010 Jun 10;66(5):695-709.

Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer’s disease.
Cortes-Canteli M, Paul J, Norris EH, Bronstein R, Ahn HJ, Zamolodchikov D, Bhuvanendran S, Fenz KM, Strickland S.

Laboratory of Neurobiology and Genetics, The Rockefeller University, New York, NY 10065, USA.

Name: Raphael Kopan
Year: 2010

Reference:

Roe CM, Fitzpatrick AL, Xiong C, Sieh W, Kuller L, Mller JP, Williams MM, Kopan R, Behrens MI and Moris JC: Cancer linked to Alzheimer disease but not vascular dementia. Neurology (2010) 74:106-112. PMC2809029

Name: Brian Carpenter
Year: 2010

Reference:

Sakai EY, Carpenter BD. Linguistic features of power dynamics in triadic dementia diagnostic conversations. Patient Education and Counseling. In Press. 10.1016/j.pec.2010.09.020

Name: Yvette Sheline
Year: 2010

Reference:

Sheline YI, Morris JC, Price JL, Yan Z, Liu C, Dixit S, Benzinger T, D’Angelo G, Snyder AZ, Fagan A, Goate, A. APOE4 Allele Disrupts Resting State fMRI Connectivity in the Absence of Amyloid Plaques or Decreased AB42. J Neurosci,Dec 2010 15;30(50):17035-40. PMCID:PMC3023180

Name: Alison Goate
Year: 2010

Reference:

Sheline YI, Morris JC, Snyder AZ, Price JL, Yan Z, D’Angelo G, Liu C, Dixit S, Benzinger T, Fagan A, Goate A, Mintun MA. APOE4 allele disrupts resting state fMRI connectivity in the absence of amyloid plaques or decreased CSF Aβ42. J Neurosci. 2010; 30(50):17035-40.

Name: Anne Fagan
Year: 2010

Reference:

Name: Yvette Sheline
Year: 2010

Reference:

Sheline YI, Raichle ME, Snyder AZ, Morris JC, Head D, Wang S, Mintun MA. Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly. Biol Psychiatry 2010; 15:584-7. PMCID: PMC2829379.

Name: Raphael Kopan
Year: 2010

Reference:

Tong, Y., H. Yamaguchi, E. Giaime, S. Boyle, R. Kopan, R.J. Kelleher, 3rd, and J. Shen: Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice. Proc Natl Acad Sci USA (2010) 107:9879-9884. PMC2906862

Name: David Balota
Year: 2010

Reference:

Tse CS, Balota DA, Roediger HL. The benefits and costs of repeated testing on the learning of face-name pairs in healthy older adults. Psychology & Aging 2010; 25: 833-845. PMCID: 2990807.

Name: Monique Williams
Year: 2010

Reference:

Williams MM, Meisel MM, Williams J, Morris JC. An interdisciplinary outreach model of African American recruitment for Alzheimer’s Disease research, The Gerontologist 2010; doi: 10.1093/geront/gnq098

Name: Monique Williams
Year: 2010

Reference:

Williams MM, Scharff DP, Mathews KJ, Hoffsuemmer JS, Jackson P, Morris JC, Edwards DF. Barriers and facilitators of African American participation in Alzheimer’s disease biomarker research. Alzheimer Disease & Associated Disorders 2010; 24 Suppl:S24-S29. PMCID:PMC2939138

Name: Robert Mach
Year: 2010

Reference:

Zeng C, Pan F, Jones LA, Lim MM, Griffin EA, Sheline YI, Mintun MA, Holtzman DM, Mach RH. Evaluation of 5-ethynyl-2’-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system. Brain Research 2010; 1319: 21-32. PMID: 20064490.

Name: Raphael Kopan
Year: 2010

Reference:

Zhao G, Liu Z, Ilagan MX and Kopan R: γ-Secretase composed of PS1/Pen2/Aph1a can cleave Notch and amyloid precursor protein in the absence of nicastrin. J Neurosci (2010) 30:1648-1656. PMC2853942

Name: Raphael Kopan
Year: 2010

Reference:

Zhao G, Liu Z, Ilagan MX and Kopan R: γ-Secretase composed of PS1/Pen2/Aph1a can cleave Notch and amyloid precursor protein in the absence of nicastrin. J Neurosci (2010) 30:1648-1656. PMC2853942

Name: Randall Bateman
Year: 2009

Reference:

Bateman RJ, Siemers ER, Mawuenyega KG, Wen G, Browning KR, Sigurdson WC, Yarasheski KE, Friedrich SW, Demattos RB, May PC, Paul SM, Holtzman DM. A Gamma-Secretase Inhibitor Decreases Amyloid-Beta Production in the Central Nervous System. Ann Neurol. 2009 Jul;66(1):48-54. PMID: 19360898

Name: Anne Fagan
Year: 2009

Reference:

Britschgi M, Olin CE, Johns HT, Takeda-Uchimura Y, LeMieux MC, Rufibach K, Rajadas J, Zhang H, Tomooka B, Robinson WH, Clark CM, Fagan AM, Galasko DR, Holtzman DM, Jutel M, Kaye JA, Lemere CA, Leszek J, Li G, Peskind ER, Quinn JF, Yesavage JA, Ghiso JA, Wyss-Coray T. Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer’s disease. Proceedings of the National Academy of Science USA, 2009; 106:12145-50. PMCID: PMC2715538

Name: Anne Fagan
Year: 2009

Reference:

Cairns NJ, Ikonomovic MD, Benzinger T, Storandt M, Fagan AM, Shah AR, Taylor-Reinwald L, Carter D, Felton A, Holtzman DM, Mintun MA, Klunk WE, Morris JC. Absence of Pittsburgh Compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease. Archives of Neurology, 2009; 66:1557-62. PMCID: PMC2796200

Name: Robert Mach
Year: 2009

Reference:

Chu W, Rothfuss J, Chu Y, Zhou D, Mach RH. Synthesis and In Vitro Evaluation of Sulfonamide Isatin Michael Acceptors as Small Molecule Inhibitors of Caspase-6. J. Med. Chem. 2009; 52: 2188-2191. PMID: 19326941

Name: Anne Fagan
Year: 2009

Reference:

Clifford DB, Fagan AM, Holtzman DM, Morris JC, Teshome M, Shah AR, Kauwe JS. CSF biomarkers of Alzheimer disease in HIV-associated neurologic disease. Neurology, 2009; 73:1982-87. PMCID: PMC2790234

Name: Anne Fagan
Year: 2009

Reference:

Duchek JM, Balota DA, Tse CS, Holtzman DM, Fagan AM, Goate AM. The utility of intraindividual variability in selective attention tasks as an early marker for Alzheimer’s disease. Neuropsychology, 2009; 23:746-58. PMCID: PMC2779520

Name: Anne Fagan
Year: 2009

Reference:

Fagan AM, Head, D, Shah AR, Marcus D, Mintun M, Morris JC, Holtzman DM. Decreased cerebrospinal fluid AÎ²42 correlates with brain atrophy in cognitively normal elderly. Annals of Neurology, 2009, 65:176-183. PMCID: PMC2763631

Name: Anne Fagan
Year: 2009

Reference:

Fagan AM, Mintun MA, Shah AR, Aldea P, Roe CM, Mach RH, Marcus D, Morris JC, Holtzman DM. Cerebrospinal fluid tau and ptau181 increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimerâ€™s disease. EMBO Molecular Medicine, 2009; 1:371-80. PMCID: PMC2806678

Name: Raphael Kopan
Year: 2009

Reference:

Hass MR, Sato C, Kopan R, Zhao G. Presenilin: RIP and beyond. Semin Cell Dev Biol. 2009, 20:201-210.PMCID: PMC2693421

Name: Anne Fagan
Year: 2009

Reference:

Hinrichs AL, Mintun MA, Head D, Fagan AM, Holtzman DM, Morris JC, Goate AM. Cortical binding of Pittsburgh Compound B, an endophenotype for genetic studies of Alzheimer’s disease. Biological Psychiatry, 2009; 67:581-583. PMCID: PMC2866645

Name: Randall Bateman
Year: 2009

Reference:

Kang JE, Lim MM, Bateman RJ, Lee JJ, Smyth LP, Cirrito JR, Fujiki N, Nishino S, Holtzman DM. Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle. Science. 2009 Nov 13;326(5955):1005-7. Epub 2009 Sep 24. PMID: 19779148

Name: Anne Fagan
Year: 2009

Reference:

Kauwe JS, Wang J, Mayo K, Morris JC, Fagan AM, Holtzman DM, Goate AM. Alzheimer’s disease risk variants show association with cerebrospinal fluid amyloid beta. Neurogenetics. 2009; 10:13-7. PMCID: PMC2726757

Name: Anne Fagan
Year: 2009

Reference:

Morris JC, Roe CM, Grant EA, Head D, Storandt M, Goate AM, Fagan AM, Holtzman DM, Mintun MA. Pittsburgh Compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimerâ€™s disease, Archives of Neurology, 2009; 66:1469-75. PMCID: PMC2798814

Name: Anne Fagan
Year: 2009

Reference:

Okereke OI, Xia W, Irizarry MC, Sun X, Qiu WQ, Fagan AM, Mehta PD, Hyman BT, Selkoe DJ, Grodstein F. Performance characteristics of plasma amyloid-beta 40 and 42 assays. Journal of Alzheimers Disease, 2009; 16:277-85. PMCID: PMC2737811

Name: Anne Fagan
Year: 2009

Reference:

Perrin RJ, Fagan AM, Holtzman DM. Multimodal techniques for diagnosis and prognosis of Alzheimer’s disease, Nature, 2009; 461:916-22. PMCID: PMC2810658

Name: Anne Fagan
Year: 2009

Reference:

Snider BJ, Fagan AM, Roe CM, Shah AR, Grant EA, Xiong C, Morris JC, Holtzman DM. Cerebrospinal fluid biomarkers and rate of cognitive decline in very mild dementia of the Alzheimer’s type. Archives of Neurology, 2009; 66:638-45. PMCID: PMC2759394

Name: Randall Bateman
Year: 2009

Reference:

Wildsmith KR, Han B, Bateman RJ. Method for the simultaneous quantitation of apolipoprotein E isoforms using tandem mass spectrometry. Anal Biochem. 2009 Dec 1;395(1):116-8. Epub 2009 Aug 3. PMID: 19653990

Name: Anne Fagan
Year: 2008

Reference:

Craig-Schapiro R, Fagan AM, Holtzman DM. Biomarkers of Alzheimer’s disease, Neurobiology of Disease, 2008; 35:128-140. PMCID: PMC2747727

Name: Randall Bateman
Year: 2008

Reference:

Elbert DL, Mawuenyega KG, Scott EA, Wildsmith KR, Bateman RJ. Stable isotope labeling tandem mass spectrometry (SILT): integration with peptide identification and extension to data-dependent scans. J Proteome Res. 2008 Oct;7(10):4546-56. Epub 2008 Sep 6. PMID: 18774841

Name: Anne Fagan
Year: 2008

Reference:

Kauwe JS, Cruchaga C, Mayo K, Fenoglio C, Bertelsen S, Nowotny P, Galimberti D, Scarpini E, Morris JC, Fagan AM, Holtzman DM, Goate AM. Variation in MAPT is associated with cerebrospinal fluid tau levels in the presence of amyloid-beta deposition. Proceedings of the National Academy of Science. USA, 2008; 105:8050-4. PMCID: PMC2430357

Name: Anne Fagan
Year: 2008

Reference:

Lemere CA, Oh J, Stanish HA, Peng Y, Pepivani I, Fagan AM, Yamaguchi H, Westmoreland SV, Mansfield KG. Cerebral amyloid-beta protein accumulation with aging in cotton-top tamarins: a model of early Alzheimer’s disease? Rejuvenation Research, 2008; 11:321-32 Accepted prior to April 7, 2008

Name: Randall Bateman
Year: 2007

Reference:

Bateman RJ, Munsell LY, Chen X, Holtzman DM, Yarasheski KE. Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates. J Am Soc Mass Spectrom. 2007 Jun;18(6):997-1006. Epub 2007 Feb 22. PMID: 17383190

Name: Randall Bateman
Year: 2007

Reference:

Bateman RJ, Munsell LY, Morris JC, Swarm R, Yarasheski KE, Holtzman DM. Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo. Nat Med. 2006 Jul;12(7):856-61. Epub 2006 Jun 25. PMID: 16799555

Name: Randall Bateman
Year: 2007

Reference:

Bateman RJ, Wen G, Morris JC, Holtzman DM. Fluctuations of CSF amyloid-beta levels: implications for a diagnostic and therapeutic biomarker. Neurology. 2007 Feb 27;68(9):666-9. PMID: 17325273

Name: Anne Fagan
Year: 2007

Reference:

Hu Y, Hosseini A, Kauwe JSK, Gross J, Cairns NJ, Goate AM, Fagan AM, Townsend RR, Holtzman DM Identification and validation of novel CSF biomarkers for early stages of Alzheimerâ€™s disease. Proteomics â€“ Clinical Applications, 2007; 1:1374-1384.

Name: Anne Fagan
Year: 2007

Reference:

Kauwe JS, Jacquart S, Chakraverty S, Wang J, Mayo K, Fagan AM, Holtzman DM, Morris JC, Goate AM. Extreme Cerebrospinal Fluid Amyloid Beta Levels Identify Family with Late-Onset AlzheimerÃ¢â‚¬â„¢s Disease Presenilin 1 Mutation. Annals of Neurology 2007; 61(5):446-53.

Name: Anne Fagan
Year: 2007

Reference:

Kauwe JSK, Jacquart S, Chakraverty S, Wang J, Mayo K, Mintun M, Fagan AM, Holtzman DM, Morris JC, Goate AM. Use of cerebrospinal fluid amyloid-Î² levels as an endophenotype identifies a PSEN1 mutation causing Alzheimerâ€™s disease in a late-onset family. Annals of Neurology, 2007; 61(5):446-53.

Name: Anne Fagan
Year: 2007

Reference:

Name: Raphael Kopan
Year: 2007

Reference:

Khandelwal A, Chandu D, Roe CM, Kopan R and Quatrano RS: Moonlighting activity of presenilin in plants is independent of γ-secretase and evolutionarily conserved. Proc Natl Acad Sci USA (2007) 104:13337-13342. PMC1948938

Name: Raphael Kopan
Year: 2007

Reference:

Khandelwal, A., Chandu, D., Roe, C.M., Kopan, R., and Quatrano, R.S. (2007). Moonlighting activity of presenilin in plants is independent of “-secretase and evolutionarily conserved. Proc Natl Acad Sci U S A 104, 13337-13342.

Name: Anne Fagan
Year: 2007

Reference:

Wahrle SE, Shah AR, Fagan AM, Smemo S, Kauwe JSK, Grupe A, Hinrichs A, Mayo K, Jiang H, Thal LJ, Goate AM, Holtzman DM. Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1 polymorphisms. Molecular Neurodegeneration, 2007; 12;2:7.

Name: Anne Fagan
Year: 2006

Reference:

Csernansky JG, Dong H, Fagan AM, Wang L, Xiong C, Holtzman DM, and Morris JC. Plasma cortisol and progression of dementia in subjects with Alzheimer-type dementia, American Journal of Psychiatry, 2006; 163: 2164-9.

Name: Anne Fagan
Year: 2006

Reference:

Fagan AM, Mintun MA, Mach RH, Lee S-Y, Dence CS, Shah AR, LaRossa G, Spinner ML, Klunk WE, Mathis CA, DeKosky ST, Morris JC, Holtzman DM Inverse relation between in vivo amyloid imaging load and CSF Aï¢42 in humans, Annals of Neurology, 2006; 59:512-519.

Name: Jeffrey Zacks
Year: 2006

Reference:

Zacks, J. M., Speer, N. K., Vettel, J. M., & Jacoby, L. L. (2006). Event understanding and memory in healthy aging and dementia of the Alzheimer type. Psychology & Aging, 21, 466-482. PMID: 16953710.

Name: Anne Fagan
Year: 2005

Reference:

Fagan AM, Csernansky CA, Morris JC, Holtzman DM. The search for antecedent biomarkers of Alzheimerâ€™s disease, Journal of Alzheimer Disease, 2005; 8:347-358.

Name: Anne Fagan
Year: 2005

Reference:

Hu Y, Townsend R, Fagan AM, Holtzman DM. Comparative proteomics analysis of intra- and inter-individual variation in human cerebrospinal fluid, Molecular and Cellular Proteomics, 2005; 4:2000-2009.

Name: Virginia Buckles
Year: 2004

Reference:

31. Cacchione PZ, Powlishta KK, Grant EA, Buckles VD, Morris JC. Collateral source reports in very mild to mild dementia of the Alzheimer type. In: Vellas B, Fitten LJ, Winblad B, Feldman H, Grundman M, Giacobini E, Kurz A. (Eds) Research and Practice in Alzheimer Disease (vol 9). Paris France: Serdi publishers, 2004, pp. 13-20

Name: Anne Fagan
Year: 2003

Reference:

Han X, Fagan AM, Cheng H, Morris JC, Xiong C and Holtzman DM. Cerebrospinal fluid sulfatide is decreased in subjects with incipient dementia, Annals of Neurology, 2003; 54:115-118

Name: Anne Fagan
Year: 2000

Reference:

Fagan AM, Holtzman DM. Astrocyte lipoproteins, effects of apoE on neuronal function, and role of apoE in amyloid-Beta deposition in vivo, Microscopy Research and Technique, 2000; 50:297-304.

Name: Anne Fagan
Year: 2000

Reference:

Fagan AM, Younkin LH, Morris JC, Fryer JD, Cole TG, Younkin SG, Holtzman DM. Differences in the Aï¢40/Aï¢42 ratio associated with CSF lipoproteins as a function of apolipoprotein E genotype. Annals of Neurology, 2000; 48:201-210.