The Knight ADRC has supported many investigators at Washington University and at other institutions over the years. We wish to avoid the situation where two investigators study the same research question to avoid duplication of effort and potential conflict. To determine if your topic has already been studied with our resources, please search our database. If you find that your topic or a related topic has been submitted, you may wish to contact the investigator to inquire about their findings to determine how you might proceed. You may wish to collaborate or modify your request to avoid overlap. The results below reflect requests made since online requests have been accepted. As such, not all fields will have data as certain information, such as aims, were not collected until recently. If an entry has been assigned an ID number (e.g. T1004), the full request has been submitted and is either approved, disapproved or in process. If an entry has no ID number, then it represents a submission that has not yet been reviewed. Search terms are applied across an entire requests application including variables not displayed below. A more specific, detailed search may yield better results depending upon your needs.
Search Terms:
Investigator: Jingqin Luo, Chengjie Xiong, Ming an Yang
Project Title: Random change point modele for longitudinal cognitive dementia
Date: December 21, 2021 at 5:18 pm
Request ID: D1023
Aim 1: It is hypothesized that a change point exists
Aim 2: Alzheimer’s disease patients will experience accerlerated dementa after the change point
Aim 3: We will identify the change point in visuospatial score and logical memory jointly
Aim 4: The relationship between the two change points helps clinical utilization of the two change points
Investigator: Tamara Hershey
Project Title: Case Study of Hypoglycemia vs. Controls
Date: December 21, 2021 at 5:18 pm
Request ID: D1010
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Investigator: John C. Morris
Project Title: Alzheimer mimics
Date: December 21, 2021 at 5:18 pm
Request ID: D1011
Aim 1: To increase the accuracy of diagnosis in neuropsychological and neuroimaging researches of AD
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Investigator: Tian
Project Title: Inference on diagnostic accuracy measures for diasease with three oridinal categories
Date: December 21, 2021 at 5:18 pm
Request ID: D1012
Aim 1: Inference about diagniostic measure with missing data
Aim 2: Infrence about the prob. of correctly idetifying the intermidiate stage given sen. and spe.
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Investigator: Denise Head
Project Title: Exercise, Aging, and Functional Connectivity
Date: December 21, 2021 at 5:18 pm
Request ID: D1013
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Investigator: Eberlein, Timothy
Project Title: A R pacakge for diagnostic test for three ordinal groups
Date: December 21, 2021 at 5:18 pm
Request ID: D1014
Aim 1: A paper introduces a R package for volumne under ROC surface and Youden index calculation&inference
Aim 2: The volumne ROC is built upon the paper by Chengjie Xiong 2006 Statististics in Medicine paper
Aim 3: The Alzheimer marker dataset used in Xiong’s paper is included in the R package as illustration
Aim 4: The dataset is an existing dataset already used in Xiong’s paper and the R package is public
Investigator: Dr. James Brewer
Project Title: Imaging studies of brain structure and function in aging and dementia
Date: December 21, 2021 at 5:18 pm
Request ID: D1020
Aim 1: Examine the relationship between brain atrophy and functional decline in aging and dementia
Aim 2: Examine the relationship between brain atrophy and cellular biomarkers in aging and dementia
Aim 3: Examine the relationship between brain atrophy and genetic markers in aging and dementia
Aim 4: Examine the relationship between brain atrophy and intracranial amyloid load in aging and dementia
Investigator: Catherine Roe
Project Title: Predicting Post-stroke Dementia: Brain Reserve, Cognitive Reserve, and Amyloid
Date: December 21, 2021 at 5:18 pm
Request ID: D1016
Aim 1: To obtain preliminary data for grant proposal
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Investigator: Denise Head
Project Title: Multiple Factors Influencing Brain Networks
Date: December 21, 2021 at 5:18 pm
Request ID: D1017
Aim 1: Examine age effects on brain networks across the lifespan
Aim 2: examine the influences of exercise, personality, amyloid and APOE genotype on brain networks
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Investigator: John Morris
Project Title: Cognitive reserve, brain reserve, and immediate stroke outcomes
Date: December 21, 2021 at 5:18 pm
Request ID: D1018
Aim 1: To determine whether cognitive and brain reserve factors influence immediate reaction to stroke.
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