Knight ADRC in the News

Using cerebrospinal fluid (CSF) collected from living patients, a team of researchers at Washington University School of Medicine in St. Louis has for the first time linked disease-related proteins and genes to identify specific cellular pathways responsible for Alzheimer’s genesis and progression. Because these proteins were gathered from CSF, they are a good proxy for activity in the brain, and several of them may be potential targets for therapies.

An analysis of cerebrospinal fluid has uncovered several proteins likely involved in the development and progression of Alzheimer’s disease. The study, published in the journal Nature Genetics, identified more than a dozen proteins that represent potential targets for future drug therapies designed to treat the disease, shedding light on how genetics and proteins influence the neurodegeneration seen in Alzheimer’s.

A variant called APOE4 is notorious for its link to Alzheimer’s. Can new insights into its function help stave off disease?

Head-to-head comparison of six tests reveals which ones could replace spinal taps, brain scans

New blood tests could help doctors diagnose Alzheimer’s disease faster and more accurately, researchers reported Sunday – but some appear to work far better than others.