The Knight ADRC has supported many investigators at Washington University and at other institutions over the years. We wish to avoid the situation where two investigators study the same research question to avoid duplication of effort and potential conflict. To determine if your topic has already been studied with our resources, please search our database. If you find that your topic or a related topic has been submitted, you may wish to contact the investigator to inquire about their findings to determine how you might proceed. You may wish to collaborate or modify your request to avoid overlap. The results below reflect requests made since online requests have been accepted. As such, not all fields will have data as certain information, such as aims, were not collected until recently. If an entry has been assigned an ID number (e.g. T1004), the full request has been submitted and is either approved, disapproved or in process. If an entry has no ID number, then it represents a submission that has not yet been reviewed. Search terms are applied across an entire requests application including variables not displayed below. A more specific, detailed search may yield better results depending upon your needs.
Search Terms:
Investigator: John C. Morris
Project Title: Alzheimer mimics
Date: December 21, 2021 at 5:18 pm
Request ID: D1011
Aim 1: To increase the accuracy of diagnosis in neuropsychological and neuroimaging researches of AD
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Investigator: Tian
Project Title: Inference on diagnostic accuracy measures for diasease with three oridinal categories
Date: December 21, 2021 at 5:18 pm
Request ID: D1012
Aim 1: Inference about diagniostic measure with missing data
Aim 2: Infrence about the prob. of correctly idetifying the intermidiate stage given sen. and spe.
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Investigator: Denise Head
Project Title: Exercise, Aging, and Functional Connectivity
Date: December 21, 2021 at 5:18 pm
Request ID: D1013
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Investigator: Eberlein, Timothy
Project Title: A R pacakge for diagnostic test for three ordinal groups
Date: December 21, 2021 at 5:18 pm
Request ID: D1014
Aim 1: A paper introduces a R package for volumne under ROC surface and Youden index calculation&inference
Aim 2: The volumne ROC is built upon the paper by Chengjie Xiong 2006 Statististics in Medicine paper
Aim 3: The Alzheimer marker dataset used in Xiong’s paper is included in the R package as illustration
Aim 4: The dataset is an existing dataset already used in Xiong’s paper and the R package is public
Investigator: James Galvin
Project Title: Utility of the AD8 in Mild Cognitive Impairment
Date: December 21, 2021 at 5:18 pm
Request ID: D1112
Aim 1: Determine the psychometric properties of the AD8 to discriminate MCI from healthy controls
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Investigator: Bruno M. Jedynak
Project Title: Statistical Analysis of the Progression of AD
Date: December 21, 2021 at 5:18 pm
Request ID: D1114
Aim 1: Validate the findings from ADNI data using ADRC data
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Investigator: Alison Goate
Project Title: TOMM40 and neuroimaging phenotypes
Date: December 21, 2021 at 5:18 pm
Request ID: D1111
Aim 1: Test hypothesis from Mark Sager regarding relationship between TOMM40 genotypes and neuroimaging phe
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Investigator: Carolyn Baum
Project Title: Contribution to a Metaanalysis on Apraxia
Date: December 21, 2021 at 5:18 pm
Request ID: D1116
Aim 1: To respond to a request from Francois Osiurak, PhD, for data that was already published
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Investigator: Siekyeong Kim
Project Title: Relationship of Cortical Thickness to Brain Morphology and Body Size
Date: December 21, 2021 at 5:18 pm
Request ID: D1113
Aim 1: What is the relationship between cortical thickness and head size?
Aim 2: Are there differences in the above relationship by CDR status?
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Investigator: B. Joy Snider, Anne Fagan
Project Title: CSF biomarkers and rate of cognitive decline in very mild DAT
Date: December 21, 2021 at 5:18 pm
Request ID: D1117
Aim 1: Look for correlation between CSF biomarkers and rate of decline in very mild DAT
Aim 2: look for correlation between ApoE genotype and rate of decline in very mild DAT
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