The Knight ADRC has supported many investigators at Washington University and at other institutions over the years. We wish to avoid the situation where two investigators study the same research question to avoid duplication of effort and potential conflict. To determine if your topic has already been studied with our resources, please search our database. If you find that your topic or a related topic has been submitted, you may wish to contact the investigator to inquire about their findings to determine how you might proceed. You may wish to collaborate or modify your request to avoid overlap. The results below reflect requests made since online requests have been accepted. As such, not all fields will have data as certain information, such as aims, were not collected until recently. If an entry has been assigned an ID number (e.g. T1004), the full request has been submitted and is either approved, disapproved or in process. If an entry has no ID number, then it represents a submission that has not yet been reviewed. Search terms are applied across an entire requests application including variables not displayed below. A more specific, detailed search may yield better results depending upon your needs.
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Investigator: Wabl, Matthias
Project Title: Alzheimer’s Disease and Parkinson’s Diseases Caused by Mutations in Critical Genes?
Date: [208]
Request ID: T0007
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Investigator: Finch, Caleb E. (Tuck)
Project Title: Characterization of complement factors and their association with A-beta deposits
Date: [208]
Request ID: T9912
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Investigator: Kido, Daniel
Project Title: Microhemorrrhages in the Elderly
Date: [208]
Request ID: T9903
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Investigator: Sun, Grace
Project Title: Expression of metabotropic glutamate receptor 5 and 7 mRNAs in AD brain
Date: [208]
Request ID: T9902
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Investigator: Sun, Grace
Project Title: Immunohistochemistry identification of cPLA2 and COXII in control and AD brain
Date: [208]
Request ID: T9901
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Investigator: Smith, Mark A.
Project Title: Oxidative Damage via Mitochondria-derived Free Radical Accumulation
Date: [208]
Request ID: T9908
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Investigator: Surguchov, Andrei
Project Title: Sera and CSF Synoretin in AD
Date: [208]
Request ID: T9907
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Investigator: Kennard, Malcolm
Project Title: p97
Date: [208]
Request ID: T9909
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Investigator: Miles Berger
Project Title: APOE4 dependent effects on the Complement Pathway in human CSF from across the full adult lifespan
Date: [208]
Request ID: T2201
Aim 1: Determine the effect of APOE4 copy number on complement protein levels in the CSF in neurologically normal individuals across the adult life span (age 18-80)
Aim 2: Determine the effect of APOE4 copy number on complement pathway activation in the CSF in neurologically normal individuals across the adult life span (age 18-80)
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Investigator: David Holtzman
Project Title: T cell surveillance and tau pathology in Alzheimer’s disease and primary tauopathies
Date: [208]
Request ID: T2202
Aim 1: Assess the relationship between T cell population and p-tau at different Braak stages of AD
Aim 2: Assess the relationship between T cell population and p-tau in primary tauopathies
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